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Dynamic Neurotech Podcast

#25 Stanford-Trained Electrical Engineer “Reverse Engineering the Brain” - Dr. Louis Scheffer

05 Jun 2025

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Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribeKey Moments:0:00 Introduction1:12 Journey from Electrical Engineering to Neuroscience6:45 Initial Interest in Neuroscience 8:16 What is connectomics?11:45 Parallels Between Microchip Design and Neuroscience 14:22 Probabilistic Reconstruction in Connectomics19:46 Neurons Behaving Like Brain Regions In C. Elegans22:17 Incorporating Biological Knowledge into Reconstruction Models and Techniques25:47 Humans vs ML: Neuron Image Classification 28:05 Future of Connectomics31:20 Expansion Microscopy33:19 Genetic Barcoding34:25 Synchrotrons and X-Rays34:56 Combining Techniques 35:52 Connectomics: From Flies to Larvae Zebrafish - Optical Microscopy37:19 Bee Neuroscience, Behavior, and Connectomics40:03 Mouse Connectomics: Eventually Expansion and Exploration of More Complex Animal Brains42:39 Any Possibility to Understand the Human Brain at this Level of Detail?45:07 Tips for Breaking into Connectomics and Neuroscience 50:50 Why are gap junctions hard to see?53:48 Connectomics Applied to Neuromorphic Computing55:07 Alcoholic Fruit Flies: Connectomics Applied to Human Medicine58:03 Conclusion and Contact InfoDr. Scheffer’s email: [email protected]: 3/20/2024Host: Robert Murcko

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