Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5

In this episode of EP Edge Podcast, Dr. Niraj Sharma dives deep into the clinical promise and procedural realities of LBBAP:Clinical advantages: improved LVEF, narrower QRS, lower VT/VF and AF incidence.RV protection: reduced risk of pacing-induced cardiomyopathy.Sex-specific outcomes: women with NICM + LBBB derive greater benefit.Complications: lead fracture, TR progression, microperforations, and capture failure.Future directions: integrating imaging, refining technique, and advancing lead technology This is where physiology meets precision—and where CRT is being redefined. For: Source data/infographics see EPEDGE Newsletter on LinkedInFor feedback, collaborations, or questions, email Dr. Niraj Sharma at [email protected] or connect on LinkedIn

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