EP Edge
Episodes
EP Edge Newsletter Part III: Pulsed Field Ablation Complications — Hemolysis, Coronary Spasm, Silent Stroke, Phrenic Nerve Injury, and CIED Interaction
25 Feb 2026
Contributed by Lukas
Pulsed field ablation (PFA) has rapidly transformed atrial fibrillation ablation, offering a non-thermal mechanism of myocardial injury through irreve...
EP Edge Newsletter Part II: Pulsed Field Ablation Trials — ADVENT, PULSED AF, Sphere-9, VARIPULSE, VOLT, INSIGHT, and PULSAR
18 Feb 2026
Contributed by Lukas
In this episode of the EP Edge Newsletter Podcast, we analyze the pivotal clinical trials that established pulsed field ablation (PFA) as a major tech...
EP Edge Newsletter Part I: Pulsed Field Ablation (PFA) — Electroporation, Biophysics, Engineering, Tissue Selectivity, and Lesion Formation
11 Feb 2026
Contributed by Lukas
In this foundational episode of the EP Edge Newsletter Podcast, we examine the scientific and engineering principles underlying pulsed field ablation ...
Cannabis and the Heart: Atrial Fibrillation, Arrhythmias, Stroke, Myocardial Infarction and Sudden Cardiac Risk Explained
22 Dec 2025
Contributed by Lukas
In this EP-EDGE podcast episode, Dr. Niraj Sharma, cardiac electrophysiologist, breaks down the latest evidence linking modern high-THC cannabis to ca...
When Atrial Fibrillation Ablation Fails: Have We Reached the Limit or Just the Wrong Target?
23 Nov 2025
Contributed by Lukas
In this issue, we trace the fascinating evolution of atrial fibrillation (AF) therapy — from the Cox Maze procedure to Haïssaguerre’s discovery o...
Targeting the Intrinsic Pathway: Is Factor XI Inhibition Poised to Redefine Stroke Prevention in AF: EP Edge August 2025 Issue 4A
28 Oct 2025
Contributed by Lukas
What if stroke prevention in atrial fibrillation no longer meant trading protection for bleeding risk?Factor XI inhibition—led by trials like AZALEA...
First-Line VT Ablation: Trials, Tools & Timing: EP Edge Newsletter June 2025
28 Oct 2025
Contributed by Lukas
The paradigm is shifting. Ventricular tachycardia (VT) ablation is stepping out of the shadows—from rescue therapy to first-line strategy, driven by...
Left Atrial Appendage Occlusion (LAAO): Where We Stand in 2025: EP Edge Newsletter 4B August 2025
28 Oct 2025
Contributed by Lukas
Left atrial appendage occlusion (LAAO) has evolved from a niche option for oral anticoagulation–intolerant patients to a frontline procedural strate...
Pulse Field Ablation: Promise, Peril, and the AI Revolution in EP: EP Edge Newsletter May 2025
28 Oct 2025
Contributed by Lukas
Pulse field ablation (PFA) has been hailed as the next frontier in atrial fibrillation therapy—nonthermal, ultra-selective, and lightning fast. But ...
Lifestyle Modification and Atrial Fibrillation: Redefining the role of the Electrophysiologist: EP Edge Newsletter July 2025
28 Oct 2025
Contributed by Lukas
Ablation is powerful—but lifestyle is transformative. As atrial fibrillation (AF) continues to rise globally, emerging evidence makes it clear: life...
Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5
27 Oct 2025
Contributed by Lukas
In this episode of EP Edge Podcast, Dr. Niraj Sharma dives deep into the clinical promise and procedural realities of LBBAP:Clinical advantages: impro...