Guz A.: long-term management in pediatric chronic intestinal failure

From Petah-Tikva, Israel – no map in your head? A tad east of Tel Aviv – at Schneider Children’s Medical Center, Dr. Anat Guz-Mark came to Helsinki for the ESPGHAN annual meeting, where this interview was recorded. Her particular interest and expertise lie in intestinal failure and its therapies, with surgical short-bowel syndrome, paediatric intestinal pseudo-obstruction, and a variety of congenital enteropathies among the problems that she, her patients, and her patients’ families face together. Listeners will learn her answers to five important questions:What are the common causes for chronic intestinal failure in children other than surgical short-bowel syndrome?What makes paediatric intestinal pseudo-obstruction or congenital enteropathies so challenging? Or, how do they differ from short-bowel syndrome?Although life-saving for these patients, long-term parenteral nutrition comes with risks. What complications should clinicians anticipate?What strategies are most effective in improving long-term outcomes?What do we know about long-term outcomes and quality of life for these children?She recommends the following articles for more comprehensive and detailed information than the interview could present. LiteratureDuggan CP, Jaksic T. Pediatric intestinal failure. N Engl J Med 2017 Aug 17; 377(7):666–675. doi: 10.1056/NEJMra1602650. PMID: 28813225Lezo A et al. Chronic intestinal failure in children: An international multicenter cross-sectional survey. Nutrients2022 Apr 30; 14(9):1889. doi: 10.3390/nu14091889. PMID: 35565856. PMCID: PMC9103944Norsa L et al. Nutrition and intestinal rehabilitation of children with short bowel syndrome: A position paper of the ESPGHAN Committee on Nutrition. Part 2: Long-term follow-up on home parenteral nutrition. J Pediatr Gastroenterol Nutr 2023 Aug.Demirok A et al. Pediatric chronic intestinal failure: Something moving? Nutrients 2024 Sep 3; 16(17):2966. doi: 10.3390/nu16172966. PMID: 39275281. PMCID: 11397488Dr. Guz’s favourite song: Yuval Raphael – New Day Will Rise ESPGHAN favourite Songs can be found on Spotify: Spotify Playlist

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