GeneInCell
Episodes
New Approach Methodologies (NAMs) for Replacing Animal Models in Drug Discovery | GeneInCell | 2026
05 Apr 2026
Contributed by Lukas
NAMs are changing how new drugs are developed. We discuss organoids, tissue chips, and AI-based tools, along with the growing FDA and NIH push toward ...
Growing replacement kidneys from stem cells | GeneInCell | 2026
15 Mar 2026
Contributed by Lukas
Can we grow new kidneys from stem cells? In this episode, we explore how scientists are using pluripotent stem cells to create kidney organoids that m...
Is Space Travel Safe For You? | GeneInCell | 2026
01 Mar 2026
Contributed by Lukas
What really happens to your cells under stress, in space, and during space travel? In this episode, we zoom in on the physiological, cellular, and mo...
Growing Beating Human Hearts in a Dish | Heart Organoids | GeneInCell
22 Feb 2026
Contributed by Lukas
What does it take to grow a beating human heart in the lab? This episode explores cardiac organoids—self-organizing heart tissues derived from human...
The AI Revolution in Healthcare: 2026 Innovation and Trends | GeneInCell | 2026
07 Feb 2026
Contributed by Lukas
In this episode, we explore the AI revolution in healthcare and what 2026 could look like—from smarter diagnostics and personalized treatments to au...
Engineering the Next Wave of Innovation with Synthetic Biology | GeneInCell | 2026
01 Feb 2026
Contributed by Lukas
Synthetic biology is turning cells into programmable factories, sensors, and therapies. In this episode, we explore how DNA can be engineered like cod...
Engineering Blood Vessels for Human Mini Brains | Vascularized Human Brain Organoids | GeneInCell | 2026
25 Jan 2026
Contributed by Lukas
How do you give “mini-brains” a bloodstream? This episode explores vascular brain organoids—cerebral organoids engineered with endothelial cells...
Growing Biological Computers-Brain Organoids From Human Cells | GeneInCell
18 Jan 2026
Contributed by Lukas
Brain organoids are self-organizing “mini-brains” grown from human stem cells that recapitulate key aspects of early neural development. They fire...
Building the Human Gut in a Dish From Pluripotent Stem Cells | GeneInCell | 2026
11 Jan 2026
Contributed by Lukas
Grow a “mini-gut” from stem cells—fast. This episode maps the journey from pluripotent cells to functional intestinal organoids, covering key si...
Intestinal 3D Organ Models: Organoids for Drug Testing
28 Dec 2025
Contributed by Lukas
Discover how 3D intestinal organoids—mini-gut tissues grown from stem cells—are transforming preclinical drug testing. We break down how these mod...
DNA Is Binary Code and Logic | GeneInCell | 2025
21 Dec 2025
Contributed by Lukas
DNA as code, cells as computers. We explore how binary models of genomes reveal mutational logic, why evolution mirrors open-source development, and h...
DNA Storage: Encoding Digital Data in Nature's Code | GeneInCell
30 Nov 2025
Contributed by Lukas
Silicon is hitting its limits—and our data keeps exploding. In this episode, we explore DNA as a radical new archive: a medium with hyper-dense capa...
CRISPR–Cas9 Variants for High-Fidelity Genome Editing
16 Nov 2025
Contributed by Lukas
Explore the shift from standard Cas9 nuclease—which makes double-strand breaks—to precision tools like Cas9 nickases (single-strand “nicks”) a...
Human Liver Organoids- From Stem Cells to Therapies
10 Nov 2025
Contributed by Lukas
From stem cells to therapies, this episode dives into the world of human liver organoids—how iPSCs are guided into functional “mini-livers,” the...
PiggyBac Transposons-A Switchable, High-Capacity Gene Delivery System in Living Cells
01 Nov 2025
Contributed by Lukas
How PiggyBac moves DNA in—and out—without scars. We cover transposase mechanics (TTAA-site integration and footprint-free excision), large cargo d...
Vascularization, Immune Cells, Organoids and Organ-On-Chip | GeneInCell | 2025
27 Oct 2025
Contributed by Lukas
A quick tour of next-gen models that add functional vascularization and immune cells to boost physiological relevance. And strategies (self-assembly, ...
Eyes In a Dish | Modeling Retinal Development with Pluripotent Stem Cells
19 Oct 2025
Contributed by Lukas
How lab-grown mini-retinas model human vision. In this episode, we show how iPSC-derived retinal organoids form layered photoreceptors, enable gene-ed...
Nobel Winning Breakthrough: Unpacking Peripheral Immune Tolerance | GeneInCell
12 Oct 2025
Contributed by Lukas
How FOXP3-defined Tregs prevent autoimmunity and shape therapy. We trace the discoveries by Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi, unpa...
🧬 CRISPR dCas9 Activation Systems for Gene Regulation | GeneInCell | 2025
05 Oct 2025
Contributed by Lukas
How do you turn genes on with CRISPR—without making a single cut? This episode breaks down dCas9-based activators (VP64, p300, SAM, VPR, SunTag), gu...
Gene Knockout: From Lab to Therapy | GeneInCell | 2025
29 Sep 2025
Contributed by Lukas
In this episode, we explore how turning off defective genes is becoming a crucial aspect of modern medicine. Educational only; not medical advice.
Antisense Oligonucleotides: From Sequence to Therapy
21 Sep 2025
Contributed by Lukas
Dive into the fascinating world of antisense oligonucleotides (ASOs) with this insightful podcast series. Explore the journey from genetic sequencing ...
AI's Impact on Biology and Drug Discovery | GeneInCell | 2025
14 Sep 2025
Contributed by Lukas
How modern AI is rewiring the life-science stack—from target discovery to first-in-human. This episode unpacks foundation models for proteins/RNAs, ...
Spaceflight vs. Your Body- Why Vision Suffers
07 Sep 2025
Contributed by Lukas
This episode spotlights Spaceflight-Associated Neuro-Ocular Syndrome (SANS)—a major risk where microgravity-driven fluid shifts raise eye/brain pres...
The American Biotech Landscape: Investment, Innovation, and Hubs
06 Sep 2025
Contributed by Lukas
We map the transition of science into companies in the USA. Hear how funding cycles, NIH/SBIR grants, talent pipelines, universities, CDMOs, and clini...
Microgravity and Human Health: Risks, Benefits, and Spaceflight Hazards
31 Aug 2025
Contributed by Lukas
What does space do to the body—and how can it advance medicine? We break down microgravity’s risks (fluid shifts/SANS, bone loss, muscle atrophy, ...
mRNA Vaccine Research and Therapeutic Applications
23 Aug 2025
Contributed by Lukas
Sources trace mRNA tech from basics to bedside: nucleoside-modified mRNA tames innate sensing and boosts translation; engineering across cap/UTRs/poly...
Personalized CRISPR Gene Therapy: A Medical Breakthrough | 2025
16 Aug 2025
Contributed by Lukas
This podcast discusses how CRISPR gene-editing technology is revolutionizing healthcare by making personalized gene therapy a reality. From treating g...
CRISPR-GPT: AI Automation for Gene-Editing Experiments
16 Aug 2025
Contributed by Lukas
Performing successful CRISPR-Cas9 experiments isn’t just about cutting DNA—it requires precision, programming, and a deep understanding of both th...
CAR T-Cell Therapy: Unleashing Your Body's Army Against Cancer and Beyond
16 Aug 2025
Contributed by Lukas
How reprogrammed T cells become living medicines. In clear, science-first episodes, we trace collection → engineering → infusion, highlight succes...
Organoids: Growing the Future of Medicine in Your Hand
11 Aug 2025
Contributed by Lukas
Organoids: Growing the Future of Medicine in Your Hand explores how mini-organs built from stem cells are reshaping drug discovery, disease modeling, ...