ID:IOTS - Infectious Disease Insight Of Two Specialists

137. Flucytosine

27 Apr 2026

Contributed by Lukas

Flucytosine. A much maligned antifungal, consigned to adjuvant use in Cryptococcus... WELL THAT CHANGES... well not today because the resistance barr...

136a. RIPL - Biosafety & Biosecurity

14 Apr 2026

Contributed by Lukas

Lab containment levels 1-4Safety cabinets 1-3ACDP approved list of biological agents 2-4Counterterrorism act  schedule 5 pathogensCat A and Cat B tra...

136. RIPL - VHF

13 Apr 2026

Contributed by Lukas

What could be more Rare Imported or Pathogenic than the Viral Haemorrhagic fevers?!Callum is joined again by Drs Claire Gordon and Amy Bellfield to ta...

135. Terbinafine & Griseofulvin

30 Mar 2026

Contributed by Lukas

Terbinafine! Griseofulvin!2 weird antifungals that the dermatologists use much more than us! But we here at the ID:IOTS Podcast love all our antifung...

134. The Rare and Imported Pathogens Lab (RIPL)

16 Mar 2026

Contributed by Lukas

Now this an episode, first of a triple About all the work of a lab called RIPL And we'd like to take minute now so sit right here And learn ab...

133. Echinocandins Part 2: Rezafungin

02 Mar 2026

Contributed by Lukas

Part 2 of 2 on Echinocandins! Tihana Bicanic gives a masterclass on Rezafungin, its use now and in the future, and gives an update on the relevant cl...

132. Echinocandins Part 1: the old stuff

23 Feb 2026

Contributed by Lukas

Alyssa and Jame are joined by Tihana Bicanic, to discuss the second great antifungal drug class, Echinocandins. Part 1 of 2! (this episode we discuss...

131. Biocide Bashing

09 Feb 2026

Contributed by Lukas

BIOCIDES ARE COMING FOR YOU. Find out what they are, what the benefits and harms they have, and what we can do to control their use in consumer produ...

130. Azole Antifungals

26 Jan 2026

Contributed by Lukas

Flustered by fluconazole? An ignoramus on itraconazole and isavuconazole?Puzzled by Posa? VEXED BY VORI? Never fear: You can be amazed at the Azoles...

129. Penicillin allergy 3: CEPH FAST

12 Jan 2026

Contributed by Lukas

AKA Penicillin Allergy 3: Delabel Hard With A VengeanceA departure from our semi-annual penicillin allergy episode: one on cephalosporin allergy! Jam...

128. Antibiotic tier list

25 Dec 2025

Contributed by Lukas

Yo ho ho, for our listeners dearestWe present an antibiotics tier list Ranking drugs from S to DIn a manner oh so ChristmassySo sit back relax and ha...

127. Brucella

15 Dec 2025

Contributed by Lukas

In which Callum and Jame discuss Brucellosis, named after a Scottish feminist, a disease hard to diagnose but easy to treat, as long as the treatment ...

126. Capnocytophaga

01 Dec 2025

Contributed by Lukas

It's the best pun Cal's ever done, and I don't say that lightly, son. Here's an episode on Capnocytophagia!  Support the showQues...

World Antimicrobial Awareness Week: AMR and Politics

19 Nov 2025

Contributed by Lukas

It’s World Antimicrobial Awareness Week! And did you know AMR might kill us all? The British Society of Antimicrobial Chemotherapy do, and they’ve...

124. Moulds that cause chronic subcutaneous infections

17 Nov 2025

Contributed by Lukas

SporotrichosisMycetomaChromoblastomycosis...Entomophthorales.Let's face it: you don't know anything about these diseases. That's OK: n...

123. Moulds: Dermatophytes

03 Nov 2025

Contributed by Lukas

Alyssa and Callum talk all things dermatophytes and Tinea:Tinea capitis – scalp, hairTinea corporis – trunk, limbs (ringworm)Tinea manuum/pedis - ...

122. Moulds: Rare Invasive Moulds

20 Oct 2025

Contributed by Lukas

Alyssa and Callum are joined by Dr Neil Stone to talk all things Rare, Invasive, and Mouldy. Specifically Fusarium spp., as well as Scedosporium spp. ...

121. Moulds: Mucorales

06 Oct 2025

Contributed by Lukas

Callum and Alyssa are joined by Dr Dora Corzo-Leon to discuss all things Mucorales and Mucormycosis. Listen in to hear about:Taxonomy (and why it is c...

120. Clinical Decision Support Systems with Biomerieux

22 Sep 2025

Contributed by Lukas

Jame is joined by Chloe from BioMerieux to discuss clinical decision support systems and their application in Microbiology & Infectious Disease! W...

119. The Moulds: Aspergillus part 2, invasive and chronic disease

08 Sep 2025

Contributed by Lukas

Callum and Jame are joined by Iain and Darius to talk through the clinical aspects of managing Aspergillosis with a particular focus on the most sever...

118. The Moulds: Aspergillus part 1, overview

25 Aug 2025

Contributed by Lukas

Alyssa and Callum talk through Aspergillus, the first of our Moulds series. After you hear the puns in this episode you'll be fumi(n)g at us. Tun...

117. Pasteurella

18 Aug 2025

Contributed by Lukas

Take a break from those pesky fungi to learn about another pesky gram-negative! This week it's Pasteurella. Support the showQuestions, comments, ...

116 The yeasts: Malassezia, Rhodotorula, Trichosporon, Saccharomyces

04 Aug 2025

Contributed by Lukas

In this episode Alyssa is joined by common host Callum to talk about some less common yeast pathogens: Malassezia spp., Rhodotorula ssp., Trichosporon...

115. The Yeasts: PCP/Pneumocytis jirovecii

21 Jul 2025

Contributed by Lukas

Listen to this Pretty Comprehensive Pod on PCP. Alyssa and Callum cover:EpidemiologyTaxonomy (PCP vs PJP?)Diagnosis TreatmentNote this pod episode a...

114. The Yeasts: Cryptococcus part 2, management

14 Jul 2025

Contributed by Lukas

Alyssa and Callum continue to speak to Jeremy Day about Cryptococcus, focusing on the evidence base for management. To further encapsulate your learn...

113. The yeasts: Cryptococcus part 1, overview and diagnosis

07 Jul 2025

Contributed by Lukas

In this episode we are uncovering the most cryptic of cocci, Cryptococcus!Alyssa and Callum are joined by Jeremy Day to learn all things neo(formans) ...

112. An Exacerbating Expansion on Endocarditis - part 2

23 Jun 2025

Contributed by Lukas

In this episode, Callum and Jame discuss the latest evidence base for endocarditis assessment & management, focusing on the ESC 2023 guidance. Ec...

111. An Exasperating Expansion on Endocarditis, Part 1

11 Jun 2025

Contributed by Lukas

In this episode, Callum and Jame discuss the latest evidence base for endocarditis assessment & management, focusing on the ESC 2023 guidance. Ep...

110. The yeasts: Candida part 3, C. auris and Candida resistance

26 May 2025

Contributed by Lukas

The conclusion of the Candida trilogy focuses on the rise of the Lord of the Candida resistance mechanisms: C. auris.Alyssa and Callum are joined by r...

109. The yeasts: Candida part 2, Candidaemia and invasive disease

19 May 2025

Contributed by Lukas

Yes we've done a Candida episode, but what about SECOND Candida episode?This week in the second part of the Candida Trilogy Alyssa and Callum are...

108. The yeasts: Candida part 1, overview and superficial candidiasis

12 May 2025

Contributed by Lukas

In this episode there will be puns where you yeast expect them...But more seriously, what does Candida albicans actually mean? What are yeasts anyway?...

107. Staphylococcus aureus bacteraemia (SAB) - interpreting and applying the literature

28 Apr 2025

Contributed by Lukas

What exciting times! Clinical trials into the management of SAB! SNAP publication on the horizon! But how do we interpret and apply the results of th...

106. Fungal diagnostics part 2: biomarkers, serology and molecular

14 Apr 2025

Contributed by Lukas

Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discus...

105. Fungal Diagnostics part 1: Microscopy, Culture & Identification techniques

07 Apr 2025

Contributed by Lukas

Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discus...

104. IDSA Difficult To Treat Gram negatives Guidance 2024 with Breakpoints podcast

24 Mar 2025

Contributed by Lukas

IT'S A BREAKPOINTS BREAKOUT!Jame and Callum are joined by the drugnamic duo of Julie-Ann Justo & Erin McCreary from the Breakpoints podcast t...

103. Fungal infections overview and series intro

17 Mar 2025

Contributed by Lukas

My my! Mycology?Join Callum and special co-host Alyssa for this, the first in the all new ID:IOTS Mycology Mega-series.Here we cover:What the British ...

102. AST: When there are NO breakpoints- how to use the EUCAST guidance document

03 Mar 2025

Contributed by Lukas

So now, Loyal Listener, you know all about Susceptible, Sensitive at higher doses, Resistant, MICs, ECOFFs/ECVs and how to use the EUCAST breakpoints ...

101. AST: When there ARE breakpoints - how to use the EUCAST clinical breakpoints table

24 Feb 2025

Contributed by Lukas

BREAKPOINTS. We all love them. S breakpoints... R breakpoints... dash, IE, NA... Wait, dash, IA, NA, Brackets?! LISTEN ON (and read the accompanying p...

100. AST: Rapid Identification and Molecular AST. The BCID2 & Vitek Reveal with BioMérieux

10 Feb 2025

Contributed by Lukas

Jame is joined by Kate from BioMérieux as they take a deep dive into the BCID2 and the Vitek Reveal, 2 new devices used for rapid identification and ...

99. AST: Automated Identification & Sensitivities - the Vitek2 with BioMérieux

27 Jan 2025

Contributed by Lukas

This week Jame is joined by Nick and Dal from BioMérieux as they take a deep dive into the Vitek2, one of the machines available for performing Autom...

98. Meningitis Masterclass

06 Jan 2025

Contributed by Lukas

Jame and Callum are joined by Dr Fiona McGill, lead author of the 2016 Joint Specialist Societies Meningitis Guidelines.Listen to hear an overview of ...

97. FIS 2024 part 3: Fungi, NTM, quinolones and others

23 Dec 2024

Contributed by Lukas

 HO HO HO, MERRY FISMAS!!!On the Third & Final Pod of FISmas these ID:IOTS have for you… 6 golden topics! Listen to hear about:1. Personalised ...

96. FIS 2024 part 2: Viruses

16 Dec 2024

Contributed by Lukas

HO HO HO, MERRY FISMAS!!!On the Second Pod of FISmas these ID:IOTS have for you… an all-enveloping, capsidating update on the High Consequence Infec...

95. FIS 2024 part 1: AMR & Bacteria

09 Dec 2024

Contributed by Lukas

HO HO HO, MERRY FISMAS!!!On the First Pod of FISmas these ID:IOTS have to you… a terrifying update on the Antibiotic Apocalypse! Jame and Callum att...

94. BSAC OPAT conference 2024

02 Dec 2024

Contributed by Lukas

Jame regales Callum with tales of his online adventure to the BSAC OPAT conference. Listen in to hear some updates on: implementation of OVIVA; subcut...

93. World AMR Awareness Week special: The Scottish Antimicrobial Prescribing Group (SAPG)

18 Nov 2024

Contributed by Lukas

WAAW! This week, to celebrate World AMR Awareness Week, Callum is Joined by Andrew, Fran, Jo and Simon from the Scottish Antimicrobial Prescribing Gro...

92. AST: What is resistance anyway? (S/I/R)

12 Nov 2024

Contributed by Lukas

Have you ever looked at your microbiology lab report and wondered "What does resistant mean anyway?" We're sure you have (and if you h...

91. The ID:IOTS Guide to Tetracyclines 2: Tigecycline, Eravacycline, Omadacycline

28 Oct 2024

Contributed by Lukas

They're new, they're weird, and we don't use them very much (or at all), but that won't stop your favourite ID:IOTS sounding off o...

90. IV to Oral Switch

14 Oct 2024

Contributed by Lukas

In which Jame talks about the rationale for IVOS, evidence base for the pros and cons, and then finishes by giving the UK oral switch criteria an abso...

89. Moraxella catarrhalis

30 Sep 2024

Contributed by Lukas

Moraxella means more moronic puns from Jame&Callum. A short episode for some short rods. Listen to hear about this coccobacillus, how to identify ...

88. Where are all the new antibiotics?

13 Sep 2024

Contributed by Lukas

Join Jame and Callum as they discuss this paper which examines where these new antibiotics are going, and why they aren't widely available.Notes ...

87. ID:IOTS guide to Tetracyclines

30 Aug 2024

Contributed by Lukas

Join Jame and Callum on this episode about the  ultimate 4 rings of power: Tetracyclines. The swiss army knife of antibiotics. We talk through the hi...

86. Legionella and pontiac fever

23 Aug 2024

Contributed by Lukas

Jame and Callum are joined by Lee John and Ella for this episode around the arch-villain of atypical pneumonia and the bogeyman of every spa. Yes Legi...

85. Bordetella and the Cough of 100 Days

05 Aug 2024

Contributed by Lukas

You'll be whooping with knowledge after listening to this one. Come hear all about Bordetella species. From pertussis to kennel cough you'll...

84. BIA Spring Meeting 2024

22 Jul 2024

Contributed by Lukas

The Spring Meeting of the British Infection Assocation is a must for UK infection trainees; In this week's episode Callum summarises for Jame (wh...

83. BSAC Spring Conference 2024

10 Jul 2024

Contributed by Lukas

Jame was there but Callum wasn't! The British Society for Antimicrobial Chemotherapy have several conferences throughout the year, including a Sp...

82. Microbiome 2: Microbiotoxicity

17 Jun 2024

Contributed by Lukas

In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, finishes educating Callum and Jame (mostly Cal...

81. Microbiome 1: Introduction

03 Jun 2024

Contributed by Lukas

In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, returns to talk about her favourite subject! ...

80. A Poem on POET

20 May 2024

Contributed by Lukas

Join us for this special 80th episode celebrating Jame's favourite trial.https://www.nejm.org/doi/full/10.1056/NEJMoa1808312Prep notes (including...

79. A Précis on Penicillin Binding Proteins

06 May 2024

Contributed by Lukas

Presenting: More on Penicillin-Binding-Proteins than you realistically ever need to know! What is the difference between Gram positive and negative b...

78. PK: Pharmacokinetics summary

21 Apr 2024

Contributed by Lukas

One PK table to rule them allOne table to find themOne table to bring them all And in the darkness blind them… …with awesome antibiotic PK facts y...

77. PK: Illuminating Elimination

08 Apr 2024

Contributed by Lukas

The last Pharmacokinetics episode had finally been …Excreted!  This episode  covers the ‘drug out’ bit of pharmacokinetics, including things ...

76. PK: Dithering on distribution

24 Mar 2024

Contributed by Lukas

It's the second Pharmacokinetics episode you never knew you wanted! Let’s talk about how antibiotics are distributed around the body once absor...

75. PK: Blethering about Bioavailability

11 Mar 2024

Contributed by Lukas

It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibi...

74. Nobbling the Nonfermentors: Burkholderia mallei - Glanders

25 Feb 2024

Contributed by Lukas

In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, cau...

73. SABATaddendum

13 Feb 2024

Contributed by Lukas

Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state. F...

72. IDIOTS journal club: the SABATO trial

12 Feb 2024

Contributed by Lukas

JOURNAL CLUB, YO, IT’S A SABATO!!!Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print,...

71.Nobbling the Nonfermentors: Burkholderia pseudomallei - Melioidosis

29 Jan 2024

Contributed by Lukas

In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease...

70. Part 2 FRCPath reflections and Desert Island Antibiotics

08 Jan 2024

Contributed by Lukas

In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we tal...

69. Choosing an antimicrobial

25 Dec 2023

Contributed by Lukas

How do you think about antibiotics?This Christmas we give the best gift of all: no puns in an episode.Join Jame and Callum as they talk about a method...

68. Nobbling the Nonfermentors: Burkholderia cepacia Complex

18 Dec 2023

Contributed by Lukas

Did you think the  evidence base for Stenotrophomonas was bad? Well allow  us to introduce you to Burkholderia cepacia complex!BCC is pretty niche b...

67. FIS highlights 3 - Fungal Diagnostics, Linezolid & Serotonin Syndrome, SABATO Trial, Rabies, PK/PD Dosing of Antibiotics

04 Dec 2023

Contributed by Lukas

Callum and Jame wrap up their thoughts on the recent FIS conference.  Support the showQuestions, comments, suggestions to [email protected] ...

66. FIS highlights 2 - Neurosurgical infections, parasitology reg, anti-fungals, NITCAR

27 Nov 2023

Contributed by Lukas

Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-...

65. FIS highlights 1 - SNAP trial, AMR musical, S. aureus update, IPC in LMIC

20 Nov 2023

Contributed by Lukas

Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-...

64. Let’s talk tests with Let’s Talk Micro

06 Nov 2023

Contributed by Lukas

In this episode Jame and Callum are joined by Louis, host of the let's talk micro podcast.Listen in for a discussion on what a Biomedical Scienti...

63. Nobbling the Nonfermentors: Stenotrophomonas maltophilia

23 Oct 2023

Contributed by Lukas

Ready for some startling Steno statistics? In this big 1-parter, Callum & Jame go through Stenotrophomonas maltophilia, from start to finish. Unl...

62. Nobbling the Nonfermentors: Acinetobacter Part 2: Resistance & CRAB

09 Oct 2023

Contributed by Lukas

In Part 2 of our episodes on Acinetobacter we talk abouit resistance, and then do a deep dive into the evidence base for the management of CRAB: Carba...

61. Nobbling the Nonfermentors: Acinetobacter Part 1

02 Oct 2023

Contributed by Lukas

In this episode, Callum and Jame go over the second big family of nonfermentors, Acinetobacter. In part 1 we talk about the organisms themselves, risk...

60. Nobbling the Nonfermentors: Pseudomonas Part 2 - Treatment & Resistance

11 Sep 2023

Contributed by Lukas

In part 2, we discuss the limited treatment options for pseudomonas infection, some wildcard options and the resistance mechanisms that make Pseudomon...

59. Nobbling the Nonfermentors: Pseudomonas Part 1

04 Sep 2023

Contributed by Lukas

It was a long time coming, but it’s here. Jame and Callum set off on our mini-series, Nobbling the Nonfermentors, starting with an introduction to g...

58. Mythbusting Cidal vs Static with Microbe Mail

29 Aug 2023

Contributed by Lukas

Jame and Callum were delighted to be invited as guests to the podcast Microbe Mail by host Vindana (Vin) Chibabhai. Check out the Microbe Mail podcast...

57. Antimicrobial stewardship begins at home

22 Aug 2023

Contributed by Lukas

Jame and Callum are together in person to talk about the importance of keeping your house in order. Being an infection specialist does not automatical...

56. Antibiotics, Breastfeeding and Infant Health

07 Aug 2023

Contributed by Lukas

We were delighted to be joined by Dr Anastasia "Tash" Theodosiou to talk about breastfeeding, antibiotics and the risks of antibiotic harm t...

55. The ID:IOTS annual report 2023

28 Jul 2023

Contributed by Lukas

2 years. It’s been a hell of a ride. Here’s to 2 more. Links from this episode: KASIC 1-page evidence-summary on aminopenicillins for resistant ...

54. Antibiotics for UTIs

24 Jul 2023

Contributed by Lukas

This is the urine antibiotic drug penetrance you never knew you wanted. Jame might be prouder of this than his own children. Callum, as you will be ab...

53. Clobbering CAUTI

10 Jul 2023

Contributed by Lukas

Catheter-associated UTI: Callum’s nemesis. His white whale. His Sauron. His favourite rant. Want to know how favourite? Listen on! Show notes for t...

52. Escalation Emancipation

26 Jun 2023

Contributed by Lukas

Loyal Listeners! Free yourselves from this outdated language! Emancipate your hospitals from 'Escalation antibiotics'! In today's episo...

51. Taking the Piss: Urine Culture, Unravelled

13 Jun 2023

Contributed by Lukas

The title says it all. We're going back to the lab for this discussion. Join Jame and Callum as they have an in depth discussion about the nature...

50. FRCPath exams for clinical scientists - prepping to pass

30 May 2023

Contributed by Lukas

Ever wondered what a clinical scientist is or how to become one? Are you a clinical scientist and looking to sit the FRCPath exams? Join Jame and Call...

49. Penicillin Allergy 2: Delabel Harder

06 May 2023

Contributed by Lukas

Welcome to the party pal! The penicillin allergy assessment and delabelling party, that is. Callum takes Jame through the latest evidence base in anti...

48. ECCMID highlights part 4: Antimicrobial stewardship, Antibiotics at end of life, Behaviour science and tick borne infections

01 May 2023

Contributed by Lukas

Join Callum with guests Morgan Evans, Olivia Hawkes and Katy Hill for the final(?) part of the ECCMID 2023 highlightsECCMID sessions discussed:- Antim...

47. ECCMID highlights part 3: Mythbusting, Sporotrichosis, phages, AMR, Paeds, Grand Round

28 Apr 2023

Contributed by Lukas

Join Callum with guests Andrew Seaton, Marianna Avellar, Hannah Pymont, Eva Garmendia, Sanjay Patel and Dave Hettle live from ECCMID 2023. ECCMID sess...

46. ECCMID highlights part 2: UTI antibiotic stewardship, CMV & BK, Responsible Publishing, HLH

26 Apr 2023

Contributed by Lukas

Join Callum with Guests Robert Ball, Kelly Bicknell & Rob Read live from ECCMID 2023. ECCMID sessions discussed:Antibiotic stewardship for urinar...

45. ECCMID highlights part 1: Archaea, Digitalisation and the IDSA

24 Apr 2023

Contributed by Lukas

Callum is reunited with Jame following their separation at ECCMID 2023. Callum shares some highlights including Archaea and their role in human health...

44. The Basics of Beta Lactamase Inhibitors

03 Apr 2023

Contributed by Lukas

Jame rides solo today, going over the beta-lactamase inhibitors, old and new, how to think about them and when to use them in anger. New Show notes f...

43. ABIM ID board exams - Prepping to Pass

20 Mar 2023

Contributed by Lukas

Jame and Callum are joined by the one and only Sara Dong of Febrile fame to look at the American Board of Internal Medicine's Infectious Disease ...

42. FRCPath part 1/CICE - Prepping to Pass

06 Mar 2023

Contributed by Lukas

Jame and Callum are joined by semi-recent FRCPath Microbiology part 1 exam passers Callum and Jame to discuss how best to prepare for this exam. This...

41. Bugs Without Borders: a conversation with Microbe Mail!

20 Feb 2023

Contributed by Lukas

Jame and Callum are joined by Vin from Microbe Mail to discuss the management of Difficult to Treat Resistance (DTR) Gram negative infections in South...

40. FRCPath part 2 Microbiology exam - Prepping to Pass

06 Feb 2023

Contributed by Lukas

Jame and Callum are joined by recent FRCPath Microbiology part 2 exam passers Olly and Rob to discuss how best to prepare for the exam. This is the fi...

39. ID:IOTS Journal Club: 3 days treatment for CAP

23 Jan 2023

Contributed by Lukas

It's time for journal club! Jame and Callum discuss community acquired pneumonia treatment and a paper from 2021 which examines shorter duration ...