Immune
Episodes
Immune 31: Immunology of COVID-19, part three
08 May 2020
Contributed by Lukas
Immune continues a discussion of the immune response to infection with SARS-CoV-2, including vaccines and immunity, effects of BCG and OPV, immunity p...
Immune 30: Immunology of COVID-19, part two
17 Apr 2020
Contributed by Lukas
Brianne Barker returns to continue a discussion of the immune response to infection with SARS-CoV-2, including use of steroid, coagulation in some pat...
Immune 29: Immunology of COVID-19
31 Mar 2020
Contributed by Lukas
Brianne Barker joins Immune to discuss the immune response to infection with SARS-CoV-2, including immune respones, pathogenesis, immunopathology and ...
Immune 28: Fish immunology
08 Feb 2020
Contributed by Lukas
Irene Salinas joins Immune to reveal the work of her laboratory on the evolution of mucosal immune responses in teleost fish, the oldest living bony v...
Immune 27: Trained immunity
11 Jan 2020
Contributed by Lukas
Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer. Hosts: Vincent Raca...
Immune 26: Measles erases immune memory
28 Nov 2019
Contributed by Lukas
Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect against infection with other p...
Immune 25: Remembrance of antigen encounters past
01 Nov 2019
Contributed by Lukas
The Immune team explains that short chain fatty acids produced by microbial fermentation of fiber rewire metabolism to enable the production of memory...
Immune 24: Unlucky IL-13
19 Sep 2019
Contributed by Lukas
The Immune team reveals a new type of T helper cell that drives the production of IgE, leading to allergic responses. Hosts: Vincent Racaniello, Step...
Immune 23: How to tell a mouse from a mouse
14 Aug 2019
Contributed by Lukas
The immunosomes explain that widely used inbred laboratory mice are not identical, and how to tell them apart. Hosts: Vincent Racaniello, Stephanie L...
Immune 22: Engineering B cells
31 Jul 2019
Contributed by Lukas
Immune reveals an alternative to a protective vaccine, engineered B cells that produce antiviral antibodies. Hosts: Vincent Racaniello, Stephanie Lan...
Immune 21: Islets of Langelhans
12 Jun 2019
Contributed by Lukas
Immune tackles the finding that patients with Type I diabetes have lymphocytes with both TCR and BCR that may drive the pathogenesis of the disease. H...
Immune 20: In defense of death
29 May 2019
Contributed by Lukas
The Immune trio explains how activation of the inflammasome by a bacterial protein causes blood clotting through a programmed cell death process calle...
Immune 19: Mom's the word
17 Apr 2019
Contributed by Lukas
The Immune team discusses immunization of pregnant mice to protect offspring from neonatal herpes simplex virus disease. Subscribe (free): iTunes,...
Immune 18: Biting off more TCR than you can chew
27 Mar 2019
Contributed by Lukas
The immunophiles discuss T cell antigen discovery by trogocytosis - the transfer of membrane patches among cells in close contact. Hosts: Vincent Rac...
Immune 17: Feed a macrophage, starve a tumor
13 Feb 2019
Contributed by Lukas
The immunophiles explain how metabolic rewiring of macrophages by CpG promotes clearance of cancer cells. Hosts: Vincent Racaniello, Stephanie Langel...
Immune 16: B is for Bursa
19 Jan 2019
Contributed by Lukas
The Immune team turns to chickens, which have been important in understanding the immune system, to show that infection of mature B cells is not requi...
Immune 15: Happy neu-trophil year
22 Dec 2018
Contributed by Lukas
Stephanie takes the Immune team on a tour of neutrophils, the most abundant leukocytes in mammals, including tethers and slings, neutrophil rolling, a...
Immune 14: Braking bad
14 Nov 2018
Contributed by Lukas
The Immune team explains the science behind the 2018 Nobel Prizes awarded to Allison and Honjo: checkpoint immunotherapy. Hosts: Vincent Racaniello, ...
Immune 13: Do no harm
20 Oct 2018
Contributed by Lukas
The ImmuNerds discuss how a cellular long non-coding RNA binds to an innate RNA sensor and regulates virus-induced interferon production to prevent da...
Immune 12: Systems immunology
19 Sep 2018
Contributed by Lukas
The Immune trifecta explores systems immunology, and its use in a study of immune system development in newborn children. Hosts: Vincent Racaniello, ...
Immune 11: Immunomimetic designer cells
18 Aug 2018
Contributed by Lukas
Cindy and Vincent describe the construction of a gene network that programs mammalian cells to detect and eliminate bacterial infections. Hosts: Vinc...
Immune 10: Immune goes viral
21 Jul 2018
Contributed by Lukas
The Immune team travels to the University of Maryland for ASV 2018, where they meet up with Rebecca Lynch to explore her work on broadly neutralizing ...
Immune 9: Neither mice nor lamprey lie
20 Jun 2018
Contributed by Lukas
The Immune team explores the variable lymphocyte receptors of jawless vertebrates, a system of immunity that parallels the structurally unrelated anti...
Immune 8: Staying warm with γδ T cells
25 May 2018
Contributed by Lukas
The Immune team reveals how γδ T cells that synthesize interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis. Hosts: Vin...
Immune 7: Contradictory complements in Alzheimer's disease
18 Apr 2018
Contributed by Lukas
The Immune hosts discuss how the complement system functions, and its role in early synapse loss in a mouse model of Alzheimer's disease. Hosts: Vinc...
Immune 6: Potent antiviral antibodies without somatic mutation
16 Mar 2018
Contributed by Lukas
The Immune hosts explain how antibody molecules mature, then discuss the finding in infants of potent neutralizing antibodies against respiratory sync...
Immune 5: Mother knows best about food allergies
22 Feb 2018
Contributed by Lukas
The ImmuoModulators provide a primer on mucosal defenses, and explain how sensitizing female mice to food allergens prevents allergic reactions in the...
Immune 4: Putting the immunotherapy CAR T before the cancer
23 Jan 2018
Contributed by Lukas
The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work...
Immune 3: Two epitopes, four serotypes, and a partridge in a pear tree
16 Dec 2017
Contributed by Lukas
Cindy, Steph, and Vincent discuss recent problems with dengue virus vaccine, and a bi-specific monoclonal antibody against Zika virus. Hosts: Vincent...
Immune 2: Lymphocytes after dark
25 Nov 2017
Contributed by Lukas
Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph are circadian - it is dependent on the time of day. Hosts: ...
Immune 1: Some like it hot
31 Oct 2017
Contributed by Lukas
Cindy, Steph, and Vincent launch a new podcast, Immune, and reveal how warm temperature protects against atherosclerosis by regulating monocyte migrat...