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Instigators of Change

Technology Business

Activity Overview

Episode publication activity over the past year

Episodes

How to Conquer Imposter Syndrome, and Become a Tech CEO

21 Dec 2022

Contributed by Lukas

Shellye Archambeau has encountered a lot of obstacles in life, but her ability to navigate around them has proved almost superhuman. Archambeau talks ...

Dheeraj Pandey Wants to Change CRM. Can He?

16 Nov 2022

Contributed by Lukas

When Dheeraj Pandey co-founded the cloud computing company Nutanix in 2009, the economy was shaky. Housing was turbulent. And interest rates had moved...

Why entrepreneurs ignore an aging America - at their peril

26 Oct 2022

Contributed by Lukas

After tennis great Serena Williams announced her retirement from tennis, she tweeted out an article from Joseph Coughlin, head of the MIT AgeLab. Will...

Jeff Wilke: From Amazon Exec to Rebuilding American Manufacturing

12 Oct 2022

Contributed by Lukas

When Jeff Wilke left Amazon in 2021, where - since 2016 - he had served as CEO of Amazon Worldwide Consumer, his next chapter could have focused on re...

What Evidence Shows About Who Really Succeeds in Business

28 Sep 2022

Contributed by Lukas

You might call Ethan Mollick a man obsessed. And he probably wouldn’t mind. Because Mollick - a high-profile professor at The Wharton School - is ob...

Siddhartha Mukherjee and Anand Parikh On A New Way To Fight Cancer

21 Sep 2022

Contributed by Lukas

More than 50 years ago, President Nixon announced a moonshot to cure cancer. But the cure never came. More than half a million Americans still die fro...

Why Nextdoor CEO Sarah Friar Took A Big Career Risk

14 Sep 2022

Contributed by Lukas

When Sarah Friar quit as the CFO of Square, CEO Jack Dorsey wasn't thrilled. But she felt compelled to take the leap. Friar explains why she left...

From Cute Cats to Political Upheaval: How YouTube Changed The World

07 Sep 2022

Contributed by Lukas

In 2005, a small company began offering up a way to post amateur videos on the web. YouTube operated on a shoestring, with its founders maxing out cre...

WeBuilt, WeCroaked (Rebroadcast)

31 Aug 2022

Contributed by Lukas

In the early 2000s, a baby clothes salesman was about to strike it big. His name was Adam Neumann, and his rise - and fall - has a lot to teach both f...

How one VC navigates today's volatility (Rebroadcast)

24 Aug 2022

Contributed by Lukas

Financial markets have been up and down enough to make anyone seasick. And if you're starting a company - or investing in one - it's an unce...

Why Big Money Makes Big Bets (Rebroadcast)

17 Aug 2022

Contributed by Lukas

This month, as we highlight some of our favorite episodes, we take a look at an industry that has altered the economic fortunes of the world over the ...

How AI destroys businesses... and creates new ones (Rebroadcast)

10 Aug 2022

Contributed by Lukas

This summer, we're revisiting some of our favorite shows. Including this discussion with Harvard Business School professor Karim Lakhani, which r...

Can Batteries Solve Everything? (Rebroadcast)

03 Aug 2022

Contributed by Lukas

As the summer - and lots of record-setting heat - drags on, you might wonder how we can slow global warming. But, even for a scientist and entrepreneu...

Ben Horowitz on Building Company Culture

27 Jul 2022

Contributed by Lukas

Ben Horowitz isn’t afraid to pick favorites when it comes to great CEOs. Like Andy Grove, the former head of Intel. Grove didn’t put up with any n...

Star In a Bottle: Can Fusion Solve Our Energy Crisis?

20 Jul 2022

Contributed by Lukas

Imagine if we could harness the power of a star, right here on Earth. Our energy challenges, as we know them, would disappear. That’s the promise of...

How A Tough 2022 Could Reshape Biotech

13 Jul 2022

Contributed by Lukas

From massive supply chain issues to wary investors, 2022 is turning out to be a tough year for biotech. But it's also a sector that's reshap...

Vinod Khosla’s American Story (Rebroadcast)

06 Jul 2022

Contributed by Lukas

On a week when we celebrate American indepedence, we revisit our conversation with venture capitalist Vinod Khosla. Khosla talks about coming to the U...

Why You're Managing Talent All Wrong

29 Jun 2022

Contributed by Lukas

Sure, Roger Martin used to run a business school. But that doesn't stop him from questioning the way we train captains of industry. In fact, he a...

How one VC navigates today's volatility

22 Jun 2022

Contributed by Lukas

Financial markets have been up and down enough to make anyone seasick. And if you're starting a company - or investing in one - it's an unce...

MIT's Angela Belcher on cancer, green synthesis, and getting inventions to market

15 Jun 2022

Contributed by Lukas

About a decade ago, when the President of MIT approached Angela Belcher about doing cancer research, Belcher turned her down. After all, Belcher is a ...

Should you be radically candid at work?

08 Jun 2022

Contributed by Lukas

Kim Scott admits she has made some huge mistakes as a boss - mistakes that made her kind of obsessed with becoming a better manager. She's also l...

Can a burger save us?

01 Jun 2022

Contributed by Lukas

Patrick Brown makes burgers for a living, but he’ll tell you without hesitation: he has no interest in making burgers. So how did a Stanford biochem...

Can batteries solve everything?

25 May 2022

Contributed by Lukas

You want to do what’s right for the planet. So you buy an all-electric car. Right? Well... not always. Jay Whitacre, one of the country’s foremost...

Turning pollution into jet fuel (and yoga pants)

18 May 2022

Contributed by Lukas

Sure, lots of business leaders have big dreams. But when Jennifer Holmgren tells you she wants to turn pollution into both jet fuel and yoga pants, sh...

What Smart Companies Know about Working with the Government

11 May 2022

Contributed by Lukas

Silicon Valley and Washington, D.C., aren't always two peas in a pod. The "move fast, break things" approach may not square with a caut...

Should Self-Driving Be Rethought?

04 May 2022

Contributed by Lukas

Self-driving seemed like a can’t-miss technology. Smart people were working on it. Money was poured into it. So why, decades later, aren’t you ans...

How AI destroys businesses... and creates new ones

27 Apr 2022

Contributed by Lukas

Artificial intelligence is upending the way business is done, and shifting who has the advantage. We talk with Harvard Business School's Karim La...

How to Beat Burnout and Master Recruiting

20 Apr 2022

Contributed by Lukas

Data shows that Americans are less happy than they’ve been in 50 years and - no surprise - that has implications for the work we do. Folks building ...

Why Big Money Makes Big Bets

13 Apr 2022

Contributed by Lukas

Venture capital has drawn both supporters and detractors, as it has altered the economic fortunes of the world over the last 50 years. Today, venture ...

WeBuilt, WeCroaked

06 Apr 2022

Contributed by Lukas

In the early 2000s, a baby clothes salesman was about to strike it big. His name was Adam Neumann, and his rise - and fall - has a lot to teach both f...

Our Debut: Vinod Khosla

30 Mar 2022

Contributed by Lukas

On the premiere episode of “Instigators of Change,” we talk with venture capitalist Vinod Khosla about what to watch for - and what to watch out f...

Coming Soon

21 Mar 2022

Contributed by Lukas

Instigators of Change is a Khosla Ventures podcast that explores innovative ideas, the people who come up with them, and those who invest in them. Our...