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JACC This Week

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Episodes

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Embryological Classification of Arrhythmogenic Triggers Initiating Atrial Fibrillation

11 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a groundbreaking study on the embryological origins of atrial fibrillation triggers, which could help r...

Ten Years of Leadless Cardiac Pacing

11 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster explores the evolution of leadless cardiac pacing over the past decade, highlighting its safety, efficacy, and gr...

JACC - November 12, 2024 Issue Summary

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster highlights the groundbreaking studies featured in the November 12, 2024 issue of the JACC, focusing on the emergi...

Reaffirmation of Mechanistic Proteomic Signatures Accompanying SGLT2 Inhibition in Heart Failure: a EMPEROR Validation Cohort

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses groundbreaking research on SGLT2 inhibitors and their impact on heart failure, highlighting the validat...

Comprehensive Proteomic Profiling of Human Myocardium Reveals Signaling Pathways Dysregulated in Hypertrophic Cardiomyopathy

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses groundbreaking research on hypertrophic cardiomyopathy (HCM), revealing dysregulated signaling pathways...

Complete vs. Culprit-Only Revascularization in Older Patients with Myocardial Infarction with or without ST-segment elevation

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a pivotal study on revascularization strategies in older patients with myocardial infarction, comparing...

Recaticimab Monotherapy for Non-Familial Hypercholesterolemia and Mixed Hyperlipemia: The Phase 3 REMAIN-1 Randomized Trial

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster reviews two pivotal phase three trials from China assessing the efficacy of the new monoclonal antibody, Katisha,...

Recaticimab as add-on therapy to statins for non-familial hypercholesterolaemia: the phase 3 REMAIN-2 trial

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster reviews two pivotal phase three trials from China assessing the efficacy of the new monoclonal antibody, Katisha,...

Artificial Intelligence in Cardiovascular Clinical Trials

04 Nov 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster delves into the transformative potential of artificial intelligence (AI) in cardiovascular clinical trials, guide...

Randomized Comparison of Novel Low-Dose Sirolimus-Eluting Biodegradable Polymer Stent vs. Second-Generation DES: TARGET-IV NA Trial

30 Oct 2024

Contributed by Lukas

Author Robert W. Yeh, MD, FACC, and JACC Associate Editor Celina M. Yong, MD, FACC, discuss the results of the TARGET-IV NA trial. In the trial, 1720 ...

Quality of Life After Transcatheter Tricuspid Valve Replacement: 1-Year Results From TRISCEND II Pivotal Trial

30 Oct 2024

Contributed by Lukas

In this episode of JACC, Author Suzanne Arnold, MD and JACC Associate Editor Dennis T. Ko, MD, discusses groundbreaking findings from the Tricatin-2 t...

Drug-Coated Balloon Angioplasty Of the Side Branch During Provisional Stenting: The Multicenter Randomized DCB-BIF Trial

28 Oct 2024

Contributed by Lukas

Author Shao-Liang Chen, MD, FACC, and JACC Associate Editor Celina M. Yong, MD, FACC, discuss patients with simple and true coronary bifurcation lesio...

Transcatheter Aortic Valve Replacement in Patients With Systolic Heart Failure and Moderate Aortic Stenosis: TAVR UNLOAD

28 Oct 2024

Contributed by Lukas

Author Nicolas M. Van Mieghem, MD, PhD, FACC, and JACC: Executive Associate Editor Aakriti Gupta, MD, FACC,  discuss the TAVR UNLOAD trial, which foc...

JACC - November 5, 2024 Issue Summary

28 Oct 2024

Contributed by Lukas

In the November 5, 2024 issue of JACC, Dr. Valentin Fuster summarizes the November 5, 2024 issue of the JACC, which focuses exclusively on hypertrophi...

Effect of Aficamten on Health Status Outcomes in Obstructive Hypertrophic Cardiomyopathy: Results from SEQUOIA-HCM

28 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster delves into the latest research on hypertrophic cardiomyopathy, highlighting the significant health status improv...

Effect of Aficamten on Cardiac Structure and Function in Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM CMR Substudy

28 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster explores groundbreaking research on hypertrophic cardiomyopathy, focusing on the effects of the drug aficamten on...

Impact of Aficamten on Echocardiographic Cardiac Structure and Function in Symptomatic Obstructive Hypertrophic Cardiomyopathy

28 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster delves into a groundbreaking study on the effects of the cardiac myosin inhibitor, Aficamten, on patients with ob...

Impact of Aficamten on Disease and Symptom Burden in Obstructive Hypertrophic Cardiomyopathy: Results from SEQUOIA-HCM

28 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster introduces a dedicated focus on hypertrophic cardiomyopathy, featuring a pivotal study by Dr. Martin Maron and Dr...

Standard of Care Medication Withdrawal in Patients With Obstructive Hypertrophic Cardiomyopathy Receiving Aficamten in FOREST-HCM

28 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster highlights the Forest HCM study, which focuses on the withdrawal of standard care medications in patients with ob...

Family Screening in Hypertrophic Cardiomyopathy - Identification of Relatives with Low Yield from Systematic Follow-up

28 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster dives into a pivotal study on hypertrophic cardiomyopathy, focusing on the challenges of identifying at-risk rela...

Transcatheter Valve Repair for Tricuspid Regurgitation: 1-Year Results From a Large European Real-World Registry

27 Oct 2024

Contributed by Lukas

Author Joerg Hausleiter, MD and Executive Associate Editor Aakriti Gupta, MD, FACC. discuss the TAVR UNLOAD trial, which focused on patients with mode...

Tricuspid Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: 1-year Outcomes From the TRILUMINATE Randomized Cohort

27 Oct 2024

Contributed by Lukas

JACC Associate Editor Celina M. Yong, MD, FACC, and JACC: Case Reports Editor in Chief Gilbert H. L. Tang, MD, MSc, MBA, FACC, discuss this paper publ...

FcγRIIa: A Marker of Cardiovascular Risk after Myocardial Infarction

21 Oct 2024

Contributed by Lukas

In this episode, Dr. David J. Schneider research identifies platelet FCγRIIA (PFCG) as a key biomarker for cardiovascular risk post-myocardial infarc...

JACC - October 29, 2024 Issue Summary

21 Oct 2024

Contributed by Lukas

In the October 29, 2024 issue of JACC, Dr. Valentin Fuster explores groundbreaking studies on heart failure treatments, including the impact of sacubi...

Asymptomatic versus symptomatic hypotension with sacubitril/valsartan in heart failure and reduced ejection fraction in PARADIGM-HF

21 Oct 2024

Contributed by Lukas

In this episode, researchers explore how asymptomatic versus symptomatic hypertension affects heart failure patients on sacubitril valsartan, finding ...

The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths.

21 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster reviews the Ironman trial, which studied the effects of intravenous iron on patients with heart failure and iron ...

AI-Facilitated Assessment of Built Environment Using Neighborhood Satellite Imagery and Cardiovascular Risk

21 Oct 2024

Contributed by Lukas

In this episode, Dr. Zhuo Chen and his team explore how AI-driven analysis of neighborhood satellite imagery can reveal links between the built enviro...

Aspirin Hypersensitivity in Patients with Atherosclerotic Cardiovascular Disease

21 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Foster introduces a vital review on aspirin hypersensitivity in patients with atherosclerotic cardiovascular disease, le...

JACC - October 22, 2024 Issue Summary

14 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster summarizes the pivotal October 2024 issue of the JACC Journal, focusing on the intersection of obesity and cardio...

Effect of Semaglutide on Cardiac Structure and Function in Patients with Obesity-Related Heart Failure

14 Oct 2024

Contributed by Lukas

In the October 22, 2024 issue of JACC, a podcast explores the promising benefits of semaglutide, a glucagon-like peptide receptor agonist, in treating...

Atrial fibrillation and semaglutide efficacy in obesity-related heart failure with preserved ejection fraction: STEP-HFpEF Program

14 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Foster highlights the October 2024 issue of JACC, which delves into the benefits of semaglutide for obesity-related hear...

Effects of Semaglutide on Heart Failure Outcomes in Diabetes and Chronic Kidney Disease (FLOW Trial)

14 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Foster explores the October issue of JACC, which highlights obesity and the potential benefits of glucagon-like peptide ...

The Effect of Semaglutide on Mortality and COVID-19-Related Deaths - An Analysis From the SELECT Trial

14 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Foster explores the October 2024 issue of JACC, highlighting the significant benefits of semaglutide, particularly for i...

Inflammation in Obesity-Related HFpEF: The STEP-HFpEF Program

14 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a pivotal study on inflammation's role in obesity-related heart failure with preserved ejection fractio...

JACC - The Effect of Teleprehabilitation on Adverse Events After Elective Cardiac Surgery: A Randomized Controlled Trial | EACTS 2024

11 Oct 2024

Contributed by Lukas

Dr. Sardari Nia's trial on digital cardiac counseling, presented at EACTS and published in JACC, is a randomized study of 394 patients. It investigate...

JACC - October 15, 2024 Issue Summary

07 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster summarizes the October 2024 issue of the JACC Journal, highlighting four pivotal studies on atrial fibrillation, ...

Minimum National Prevalence of Diagnosed Atrial Fibrillation inferred from California Acute Care Facilities

07 Oct 2024

Contributed by Lukas

In the October 15, 2024, issue of JACC, Dr. Valentin Fuster highlights a crucial study revealing that the prevalence of diagnosed atrial fibrillation ...

Bivalirudin vs Heparin Anticoagulation in STEMI: Confirmation of the BRIGHT-4 Results

07 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a pivotal study comparing bivalirudin and heparin anticoagulation in STEMI patients undergoing primary ...

Heart failure risk assessment using biomarkers in patients with atrial fibrillation: Analysis from COMBINE-AF

07 Oct 2024

Contributed by Lukas

In the October 15, 2024 issue of JACC, a study led by Dr. Paul Haller investigates the use of biomarkers—NT-proBNP, high-sensitive cardiac troponin ...

Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis

07 Oct 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a groundbreaking study linking urinary metal levels, particularly non-essential metals like cadmium and...

International Clinical Practice Guideline Recommendations for Acute Pulmonary Embolism: Harmony, Dissonance, and Silence.

07 Oct 2024

Contributed by Lukas

In this insightful episode of JACC, Dr. Valentin Fuster summarizes groundbreaking international clinical practice guidelines for acute pulmonary embol...

Part Two: Time to Significant Benefit of Finerenone in Patients With Heart Failure | JACC | HFSA 2024

04 Oct 2024

Contributed by Lukas

Michelle M Kittleson, MD, FACC, JACC Associate Editor, speaks with author Muthiah Vaduganathan, MD on his accepted paper concerning the FINEARTS trial...

Finerenone in Patients With a Recent Worsening Heart Failure Event: The FINEARTS-HF Trial | JACC | HFSA 2024

04 Oct 2024

Contributed by Lukas

Akshay S. Desai, MD, FACC presents his accepted HFSA presentation concerning the FINEARTS trial published in JACC, with commentary by Theresa McDonagh...

JACC - October 8, 2024 Issue Summary

30 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster highlights groundbreaking research from the October 8, 2024 issue of JACC. Key studies delve into the evolving di...

Prognostic Implications of Clinical- and Imaging Diagnostic Criteria for Myocarditis

30 Sep 2024

Contributed by Lukas

In the October 8, 2024 issue of JACC, a pivotal study explores the prognostic implications of various diagnostic criteria for myocarditis, comparing t...

Influence of subclinical atherosclerosis burden and progression on mortality

30 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses groundbreaking research on the impact of subclinical atherosclerosis on mortality, revealing insights f...

Arrhythmic Risk Stratification by Cardiovascular Magnetic Resonance Imaging in Patients with Non-ischemic Cardiomyopathy

30 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a groundbreaking study that evaluates the role of myocardial fibrosis in predicting sudden cardiac deat...

Risk of Ischemic Stroke After Patent Foramen Ovale Closure

30 Sep 2024

Contributed by Lukas

In the October 8, 2024, issue of JACC, Dr. Casper Bonison and colleagues present a study on the risks of ischemic stroke recurrence after PFO closure,...

Contemporary Training in American Critical Care Cardiology: Minnesota Critical Care Cardiology Education Summit

30 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster introduces a crucial consensus document on Critical Care Cardiology training, highlighting insights from leading ...

ACC/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2024 Appropriate Use Criteria for Multimodality Imaging in Cardiovascular Evaluation of Patients Undergoing Nonemergent, Noncardiac Surgery

30 Sep 2024

Contributed by Lukas

In this episode, experts discuss a crucial 2024 document outlining appropriate use criteria for multimodality imaging in cardiovascular evaluation bef...

Time to Significant Benefit of Finerenone in Patients with Heart Failure | HFSA 2024

28 Sep 2024

Contributed by Lukas

Michelle M Kittleson, MD, FACC, JACC Associate Editor, speaks with author Muthiah Vaduganathan, MD on his accepted paper concerning the FINEARTS trial...

JACC - October 1, 2024 Issue Summary

23 Sep 2024

Contributed by Lukas

In the October 2024 issue of JACC, Dr. Valentin Fuster highlights five diverse studies addressing key topics in cardiovascular health, from surgical o...

Outcomes of Patients Undergoing Surgery for Complete Vascular Rings

23 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster highlights a groundbreaking study on surgical outcomes for complete vascular rings, revealing that 95% of childre...

Patiromer Facilitates Angiotensin Inhibitor and Mineralocorticoid Antagonist Therapies in Patients with Heart Failure and Hyperkalemia

23 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Foster highlights a groundbreaking study published in the October 2024 issue of JACC, which explores how patiromer facil...

Relationship Between Control of Cardiovascular Risk Factors and Chronic Kidney Disease Progression, Cardiovascular Disease Events, and Mortality in Chinese Adults

23 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses groundbreaking research on the interplay between cardiovascular risk factors and chronic kidney disease...

Quantifying triglyceride-rich lipoprotein atherogenicity, associations with inflammation, and implications for risk assessment using non-HDL cholesterol

23 Sep 2024

Contributed by Lukas

In this insightful discussion from the October 1, 2024 issue of JACC, researchers reveal that triglyceride-rich lipoprotein (TRL) remnants are signifi...

Implantable Cardioverter Defibrillator and Resynchronization Therapy in Patients with Overt Chronic Kidney Disease: JACC State-of-the-Art Review

23 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster discusses a comprehensive review on the challenges and considerations of using implantable cardiography devices i...

2024 ACC/AHA Key Data Elements and Definitions for Social Determinants of Health in Cardiology

23 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster reviews a pivotal document on Social Determinants of Health (SDOH) in cardiology, highlighting their critical rol...

Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis

20 Sep 2024

Contributed by Lukas

Dr. Kaitlyn McGraw discusses her study on the relationship between urinary trace metal levels and coronary artery calcification, highlighting the role...

JACC - September 24, 2024 Issue Summary

16 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster highlights key studies from the September 24, 2024 issue of JACC, featuring groundbreaking research on the impact...

Short-term effects of lower air temperature and cold spells on myocardial infarction hospitalizations in Sweden

16 Sep 2024

Contributed by Lukas

In the September 24, 2024 issue of JACC, Dr. Ben Lee Nay and colleagues reveal that short-term exposures to lower temperatures and cold spells signifi...

Recovery of Left Ventricular Function and Long-term Outcomes in Patients with Takotsubo Syndrome

16 Sep 2024

Contributed by Lukas

In the September 24, 2024 issue of JACC, Dr. Manuel Almendro Odelia and Dr. Ivan Nunet Hill present groundbreaking research on Takotsubo syndrome, rev...

Temporal Trends in Takotsubo Syndrome - Results from the International Takotsubo Registry

16 Sep 2024

Contributed by Lukas

In the September 24, 2024 issue of JACC, Dr. Valentin Fuster explores a pivotal study on Takotsubo Syndrome, revealing significant shifts in patient d...

Predicting Long-term Clinical Outcomes of Patients with Recurrent Pericarditis

16 Sep 2024

Contributed by Lukas

In the September 24, 2024, issue of JACC, Dr. Abdullah Yashin Yaprak and his team at Cleveland Clinic unveil a groundbreaking risk prediction model fo...

2024 ACC Expert Consensus Decision Pathway on Clinical Assessment, Management, and Trajectory of Patients Hospitalized With Heart Failure Focused Update: A Report of the American College of Cardiology Solution Set Oversight Committee

16 Sep 2024

Contributed by Lukas

In the September 24, 2024, JACC issue, Dr. Valentin Fuster presents the latest expert consensus on heart failure management, updating the 2019 guideli...

Interactions of Sleep Apnea with the Pathophysiology of Cardiovascular Disease, Part 1: JACC State-of-the-Art Review

16 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster dives into a comprehensive review of obstructive sleep apnea, exploring its complex interactions with cardiovascu...

JACC - September 17, 2024 Issue Summary

09 Sep 2024

Contributed by Lukas

In this episode, Valentin Fuster reviews the September 17, 2024, JACC issue, highlighting pivotal studies on metabolic surgery's impact on cardiovascu...

Adverse Cardiovascular Outcomes in Patients with Obstructive Sleep Apnea and Obesity: Metabolic Surgery versus Usual Care

09 Sep 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster reviews a groundbreaking study comparing metabolic surgery to traditional care for patients with obesity and obst...

Effect of Evogliptin on the Progression of Aortic Valvular Calcification

09 Sep 2024

Contributed by Lukas

In the September 17, 2024 issue of JACC, Dr. Jai Quan Song and colleagues explore whether the DPP-4 inhibitor, abrogating, can slow the progression of...

Effects of Sotagliflozin on Health Status in Patients With Worsening Heart Failure: Results From SOLOIST-WHF

09 Sep 2024

Contributed by Lukas

In the September 17, 2024 issue of JACC, Valentin Fuster discusses a study on sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, which shows modest impr...

Prognostic value of plasma IgG N-glycome traits in pulmonary arterial hypertension

09 Sep 2024

Contributed by Lukas

In this September 17, 2024 JACC issue, Dr. Zhi Jian Zhang and colleagues unveil a groundbreaking study on pulmonary arterial hypertension (PAH) that i...

Genotype Guided Antiplatelet Therapy: JACC Review Topic of the Week

09 Sep 2024

Contributed by Lukas

In this episode of JACC, Valentin Fuster examines genotype-guided antiplatelet therapy, emphasizing its potential to tailor treatments based on geneti...

RESHAPE-HF2 Trial Findings | ESC 2024

06 Sep 2024

Contributed by Lukas

Dr. Marcus Anker, presenting at ESC, discussed the RESHAPE HF2 trial's findings on transcatheter edge-to-edge repair for secondary mitral regurgitatio...

Effect of Screening for Undiagnosed Atrial Fibrillation and on Stroke Prevention | ESC Congress

05 Sep 2024

Contributed by Lukas

Xiaoxi Yao, MPH, MS, PhD, FACC, JACC Associate Editor, interviews Renato Lopes, MD, PhD, FACC, author of the GUARD-AF trial published in JACC and pres...

Insights from the SEQUOIA-HCM Trial and SEQUOIA-HCM CRM Substudy | ESC 2024

03 Sep 2024

Contributed by Lukas

Michelle M. Kittleson, MD, PhD, FACC, JACC Associate Editor and John A. Spertus, MD, MPH, FACC discuss the evaluation of the cardiac myosin inhibitor,...

Insights from the SEQUOIA-HCM Trial and SEQUOIA-HCM CRM Substudy | ESC 2024

03 Sep 2024

Contributed by Lukas

Michelle M. Kittleson, MD, PhD, FACC, JACC Associate Editor and John A. Spertus, MD, MPH, FACC discuss the evaluation of the cardiac myosin inhibitor,...

JACC - September 10, 2024 Issue Summary

02 Sep 2024

Contributed by Lukas

In the September 10, 2024, issue of JACC, Dr. Valentin Fuster highlights groundbreaking research on lipid exposure in early adulthood and its link to ...

Prediction of Cumulative Exposure to Atherogenic Lipids During Early Adulthood

02 Sep 2024

Contributed by Lukas

In the September 10, 2024, JACC issue, Dr. Valentin Fuster highlights a pivotal study showing that a single cholesterol measurement in young adults ca...

Serial Shock Severity Assessment Within Seventy-Two Hours after Diagnosis: A Cardiogenic Shock Working Group Report

02 Sep 2024

Contributed by Lukas

In the September 10, 2024, JACC issue, Dr. Valentin Fuster discusses a pivotal study on cardiogenic shock, revealing that early and frequent reassessm...

Triglyceride Levels, Alirocumab Treatment, and Cardiovascular Outcomes After an Acute Coronary Syndrome

02 Sep 2024

Contributed by Lukas

In the September 10, 2024, issue of JACC, the study by Dr. Doron Seeker and colleagues investigates alirocumab's impact on cardiovascular outcomes rel...

Association of Postnatal Opioid Exposure and 2-year Neurodevelopmental Outcomes in Infants Undergoing Cardiac Surgery

02 Sep 2024

Contributed by Lukas

In this September 10th, 2024 issue of Jack, Dr. Michael Ogburn's study highlights a troubling association between high postnatal opioid exposure and p...

Serial Shock Severity Assessment: Some Answers. Still Many Questions. | ESC 2024

31 Aug 2024

Contributed by Lukas

Rasha K. Al-Lamee, MD, PhD, JACC Deputy Editor and Navin K. Kapur MD discuss the work from the Cardiogenic Shock Working Group, which is an academic r...

Insights from RESHAPE-HF2 Trial | ESC 2024

31 Aug 2024

Contributed by Lukas

Aakriti Gupta, MD, FACC, JACC Executive Associate Editor, and Stefan D. Anker, MD, discuss the insights from the RESHAPE-HF2 trial - an eight-year stu...

A Secondary Analysis of DANFLU-1 Trial - High vs Standard Dose Influenza Vaccine in CKD | ESC 2024

31 Aug 2024

Contributed by Lukas

Khurram Nasir, MBBS, FACC, JACC Associate Editor and Tor Biering-Sorenson, MD, MPH, PhD, discuss the importance of influenza vaccines for patients wit...

Updates from the STEP-HFpEF Trial | ESC 2024

30 Aug 2024

Contributed by Lukas

Neha J. Pagidipati, MD, FACC, JACC Associate Editor and Mikhail Kosiborod, MD, FACC discuss an exciting secondary analysis of the STEP-HFpEF program, ...

Updates from the SELECT Trial: Outcomes by Sex | ESC 2024

30 Aug 2024

Contributed by Lukas

Neha J. Pagidipati, MD, FACC, JACC Associate Editor and Subodh Verma MD, PhD explore a secondary analysis of the SELECT trial, a landmark study invest...

An Analysis From the SELECT Trial - COVID-19| ESC 2024

30 Aug 2024

Contributed by Lukas

Harlan Krumholz, MD, FACC, JACC Editor-in-Chief, and Benjamin M. Scirica, MD, MPH, FACC, discuss the surprising benefits of semaglutide beyond weight ...

Insights from the FLOW Trial | ESC 2024

30 Aug 2024

Contributed by Lukas

Neha J. Pagidipati, MD, FACC, JACC Associate Editor, and Richard Pratley, MD, discuss insights from the FLOW trial – revealing that semaglutide redu...

JACC - September 3, 2024 Issue Summary

26 Aug 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster reviews five pivotal studies from September 2024, focusing on antithrombotic strategies and diabetes treatments. ...

Antithrombotic Strategies in Atrial Fibrillation After ACS and/or PCI: A 4-way Comparison from AUGUSTUS

26 Aug 2024

Contributed by Lukas

Dr. Valentin Fuster discusses the Augustus trial's groundbreaking findings on antithrombotic strategies for atrial fibrillation patients post-acute co...

Anticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Watchman FLX Left Atrial Appendage Occlusion

26 Aug 2024

Contributed by Lukas

In the September 3, 2024, issue of JACC, Dr. Samuel Reinhart and team find that using direct oral anticoagulants alone is associated with fewer advers...

Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Multinational, Federated Analysis of LEGEND-T2DM

26 Aug 2024

Contributed by Lukas

In the September 3, 2024, JACC issue, a major study evaluates the cardiovascular outcomes of second-line antihyperglycemic agents in type 2 diabetes, ...

Continuous Rhythm Monitoring with Implanted Loop Recorders in Children and Adolescents with Brugada Syndrome

26 Aug 2024

Contributed by Lukas

In the September 3, 2024, issue of JACC, Dr. Valentin Fuster introduces a pivotal study on Brugada syndrome in children and adolescents. This research...

Antithrombotic Strategies for Patients with Peripheral Artery Disease: JACC Scientific Statement

26 Aug 2024

Contributed by Lukas

In the September 3rd, 2024 issue of JACC, a new scientific statement delves into antithrombotic strategies for peripheral artery disease (PAD), highli...

JACC - August 27, 2024 Issue Summary

19 Aug 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster covers four original papers focusing on cardiovascular disease. Highlights include the effectiveness of semagluti...

Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials

19 Aug 2024

Contributed by Lukas

Dr. Valentin Fuster discusses a study on the efficacy of semaglutide for treating obesity-related heart failure with preserved ejection fraction, high...

The Off-Treatment Effects of Olpasiran on Lipoprotein(a) Lowering: OCEAN(a)-DOSE Extension Period Results

19 Aug 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster explores findings from the Phase 2 OCEAN-LDO trial assessing the off-treatment effects of the RNA-based drug alpc...

Low-Dose Rivaroxaban Plus Aspirin in Fragile Patients After Lower Extremity Revascularization

19 Aug 2024

Contributed by Lukas

Dr. Valentin Fuster discusses a study on the effects of low-dose rivaroxaban combined with aspirin in fragile patients after lower extremity revascula...

Deep Learning-Based Electrocardiogram Analysis Predicts Biventricular Dysfunction and Dilation in Congenital Heart Disease

19 Aug 2024

Contributed by Lukas

Dr. Valentin Fuster evaluates a deep learning model designed to predict left and right ventricular dysfunction and dilation in congenital heart diseas...

Structural Cardiac Interventions in Patients with Heart Failure: JACC Scientific Statement

19 Aug 2024

Contributed by Lukas

In this episode, Dr. Valentin Fuster provides an overview of a scientific statement on structural cardiac interventions in heart failure. It details a...

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