JAMA+ AI Conversations
Episodes
AI at the Policy Table
07 May 2026
Contributed by Lukas
As artificial intelligence increasingly shapes population health decisions, evidence and accuracy matter. In this episode of JAMA+ AI Conversations, A...
AI Drug Safety in Pregnancy
23 Apr 2026
Contributed by Lukas
Why can signals that appear consistent across many studies still reflect shared bias; how do sibling comparisons help recalibrate cumulative evidence;...
Understanding Disease Trajectories With AI
09 Apr 2026
Contributed by Lukas
How might AI amplify epidemiological insight into neurodegenerative and systemic disease? JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, speaks with...
AI Chatbots and Youth Mental Health
26 Mar 2026
Contributed by Lukas
What are the safety, evidence standards, and transparency needed for AI chatbots used in mental health contexts, particularly for young people. John T...
Leaping Forward Into… What? An Interview With Dr Robert Wachter
12 Mar 2026
Contributed by Lukas
Dr Robert Wachter, chair of the Department of Medicine at UC San Francisco, speaks with JAMA+ AI Editor in Chief Roy Perlis about his new book, "A Gia...
AI and "Do No Harm"
26 Feb 2026
Contributed by Lukas
In this episode, JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, speaks with David Wu, MD, PhD, and Adam Rodman, MD, MPH, about what safe clinical u...
Stumbling Toward AI in the Clinic
12 Feb 2026
Contributed by Lukas
In this episode of JAMA+ AI Conversations, Editor in Chief Roy Perlis and Associate Editor Yulin Hswen debate recent articles highlighted in JAMA+ AI,...
Chatting With a Chatbot: The History of the First Clinical Chatbots, Straight From an LLM
29 Jan 2026
Contributed by Lukas
A large language model (LLM) details the history of 2 early chatbots, ELIZA and PARRY, in conversation with JAMA+ AI Editor in Chief Roy Perlis. This ...
Seeing Health Through the Eye and AI
15 Jan 2026
Contributed by Lukas
Retinal images are becoming powerful windows into human health. Cecilia Lee, MD, MS, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen to explore h...
Multiple Reasoning Models and the Future of AI Chatbots
30 Dec 2025
Contributed by Lukas
AI chatbots have advanced rapidly, incorporating new reasoning architectures that reshape decision-making and medical education. Jonathan Chen, MD, Ph...
Discussing the Latest Research in AI and Health
18 Dec 2025
Contributed by Lukas
JAMA+ AI Editor in Chief Roy Perlis and Associate Editor Yulin Hswen discuss some of the most cited AI papers in 2025 across the JAMA Network. A littl...
Designing AI for Uncertainty: A Conversation With Eric Horvitz
20 Nov 2025
Contributed by Lukas
How can AI systems reason safely in the open world of medicine? JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, talks with Eric Horvitz, MD, PhD, Chi...
AI for Drug Discovery
06 Nov 2025
Contributed by Lukas
Will AI usher in a new era of rapid drug discovery? In this episode of JAMA+ AI Conversations, Editor in Chief Roy Perlis interviews Ajamete Kaykas, C...
AI, Health, and Health Care
13 Oct 2025
Contributed by Lukas
Derek Angus, MD, MPH, joins JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, to discuss a special communication from JAMA Summit: Artificial Intelligence...
AI, Health Care, and What to Expect in 2026
09 Oct 2025
Contributed by Lukas
How will 2026 shape the world of AI in health? Editor in Chief Roy Perlis and Associate Editor Yulin Hswen discuss in this special episode marking one...
Maintaining Safety and Trust When Patients Engage Google: A Conversation With Dr Michael Howell
18 Sep 2025
Contributed by Lukas
How is Google Search evolving with AI and how do we ensure that language models maintain safety? JAMA+ AI Editor in Chief Roy Perlis, MD, talks with M...
AI in Women's Health
05 Sep 2025
Contributed by Lukas
In this special edition of JAMA+ AI Conversations, editor in chief Roy Perlis is joined by Linda Brubaker, editor in chief of JAMA+ Women's Health and...
Navigating Transparency and Trust With AI in Health Care
21 Aug 2025
Contributed by Lukas
Michelle Mello, JD, PhD, MPhil, professor of law and health policy at Stanford University, joins JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, to disc...
Changing Opinions About AI in Health Care
07 Aug 2025
Contributed by Lukas
In this episode of JAMA+ AI Conversations, Microsoft CMO David Rhew, MD, discusses his journey from clinical practice to technology leadership, rapid ...
From the JAMA Network: Socially Assistive Robots, Part 2
05 Aug 2025
Contributed by Lukas
In this follow-up to a 2017 interview with JAMA Medical News, the University of Southern California's Maja Matarić, PhD, the computer scientist who p...
Can AI Improve Cost-Effectiveness of 3D Total-Body Photography?
24 Jul 2025
Contributed by Lukas
3D total-body photography is used to detect lesions and melanoma in patients at high risk of developing skin cancer. The cost-effectiveness of this te...
Checking in Between Checkups: An AI App to Track Asthma Symptoms
10 Jul 2025
Contributed by Lukas
Despite recommendations from health care professionals, most patients with asthma do not track their symptoms, leaving limited data to help them discu...
Harnessing AI and Genomics in Clinical Trial Enrollment
26 Jun 2025
Contributed by Lukas
The Dana-Farber Cancer Institute (DFCI)'s MatchMiner tool was developed to increase historically low clinical trial enrollment rates in adults with ca...
AI-Based Analysis for Parkinsonism
13 Jun 2025
Contributed by Lukas
Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues te...
Should Employers Offer Digital Mental Health Programs to Support Workforce Well-Being?
29 May 2025
Contributed by Lukas
Employer-sponsored digital health solutions help patients with behavioral health conditions increase workplace productivity. Yulin Hswen, ScD, MPH, As...
When Do Nudges Help?
16 May 2025
Contributed by Lukas
Susan Athey, PhD, of Standford University joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her research on machine learning to target...
Real-World Performance of AI in Screening for Diabetic Retinopathy
18 Apr 2025
Contributed by Lukas
Diabetic retinopathy remains a leading cause of preventable blindness worldwide, and AI may facilitate screening, if such models continue to perform w...
Can Open-Source LLMs Compete With Proprietary Ones for Complex Diagnoses?
04 Apr 2025
Contributed by Lukas
A recent study published in JAMA Health Forum suggests that institutions may be able to deploy custom open-source large language models (LLMs) that ru...
Rethinking Race in Prenatal Screening for Open Neural Tube Defects
28 Mar 2025
Contributed by Lukas
Correction: This podcast has been updated to add additional context on the frequency of false positives. Open neural tube defects affect approximatel...
AI's Role in Advancing Equity for Individuals With Developmental Disabilities
21 Mar 2025
Contributed by Lukas
Artificial intelligence (AI) in health care is advancing, despite concerns about how its use may impact health disparities. Dimitri Christakis, MD, MP...
Prescreening for Clinical Trial Eligibility Using Large Language Models
14 Mar 2025
Contributed by Lukas
A recent study showed AI-assisted screening using a large language model tool reduced time to determine trial eligibility compared with manual methods...
Machine Learning for Earlier Diagnosis of Schizophrenia
07 Mar 2025
Contributed by Lukas
In a recent study published in JAMA Psychiatry, researchers reported that a machine learning model was able to stratify risk for subsequent diagnosis ...
Language Equity in Health Technology
28 Feb 2025
Contributed by Lukas
AI can play a role in addressing language barriers in health care. In a recent Editorial in JAMA Network Open, Pilar Ortega, MD, MGM, of the Universit...
AI Guided Diagnostic-Quality Lung Ultrasound
21 Feb 2025
Contributed by Lukas
Lung ultrasound aids in the diagnosis of patients with dyspnea but requires technical proficiency for image acquisition. Cristiana Baloescu, MD, MPH, ...
Diagnosis and Treatment of Infectious Disease Using AI
14 Feb 2025
Contributed by Lukas
A recent study in JAMA Network Open evaluates the use of machine learning algorithms to assess the management of urinary tract infection (UTI). Author...
Older Adults' Use of Digital Health Technology
07 Feb 2025
Contributed by Lukas
Digital health technologies, including patient portals, are widely used by older adults, as described in a recent study published in JAMA Network Open...
Patient Satisfaction With AI-Generated Responses
31 Jan 2025
Contributed by Lukas
How do patients feel about the quality of AI-generated responses to their messages to clinicians? Author Eleni Linos, MD, DrPH, of Stanford joins JAMA...
Drafting Replies to Patient Messages With AI
24 Jan 2025
Contributed by Lukas
The burden of responding to clinician inbox messages may be a contributor to burnout. Eden English, MD, of UCHealth joins JAMA+ AI Editor in Chief Roy...
Bioethics and AI
17 Jan 2025
Contributed by Lukas
With accelerating global adoption of AI, countries are developing ethical AI frameworks to prevent harm to the most vulnerable populations. Maria Vill...
AI-Based Suicide Screening for American Indian Patients
10 Jan 2025
Contributed by Lukas
American Indian and Alaska Native communities have higher rates of suicide than any other racial or ethnic group in the US. A recent study published i...
Comparing Early Hospital Warning Scores for Clinical Deterioration
03 Jan 2025
Contributed by Lukas
How can hospitals use early warning score tools to risk stratify patients without adding to alarm fatigue? Dana Edelson, MD, MS, of the University of ...
AI Chatbots in Clinical Practice
27 Dec 2024
Contributed by Lukas
Chatbots may have a role in enhancing clinical care, but the best way to apply them remains a work in progress. Jonathen Chen, MD, PhD, and Ethan Goh,...
How Health Systems Can Collaborate on AI Tools
20 Dec 2024
Contributed by Lukas
In a recent Viewpoint published in JAMA, Michael Pencina, PhD, of Duke University, argued for a federated registration system for AI tools deployed in...
AI-Enabled Ultrasound Could Improve Global Obstetric Care
13 Dec 2024
Contributed by Lukas
In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Jeffrey Stringer, MD, University of Nort...
AI as Interpreter in the Clinic
06 Dec 2024
Contributed by Lukas
Effective communication is essential in medicine, yet language barriers can result in suboptimal care. AI holds promise for bridging these gaps, enhan...
AI and the FDA
22 Nov 2024
Contributed by Lukas
A recent Special Communication published in JAMA points out that the FDA has already approved nearly 1000 devices using AI. Author Robert M. Califf, M...
The Ethics of AI as Clinical Decision Maker
15 Nov 2024
Contributed by Lukas
A recent JAMA Cardiology essay argues that medicine is not just a technical endeavor, it's also a moral endeavor, and a robot does not have moral agen...
AI and the National Academy of Sciences
08 Nov 2024
Contributed by Lukas
Widespread adoption of AI raises questions about accountability, transparency, and reproducibility. Marcia McNutt, PhD, president of the National Acad...
Getting Technology Into the Clinic
18 Oct 2024
Contributed by Lukas
Getting genuinely useful new technologies, from wearables to clinical decision support, into the clinic has proven to be surprisingly challenging. Tan...
What Lessons Does the VA's Experience Building Electronic Health Records Hold for AI?
08 Oct 2024
Contributed by Lukas
What hard lessons did the US Department of Veterans Affairs (VA) learn in 3 decades of EHR development, and what can it teach us about building better...
The Future of Wearables and Mobile Devices for Patient Care
05 Jul 2024
Contributed by Lukas
Can data from wearable devices and electronic health records enhance quality improvement in health care? In this Q&A, Sachin Kheterpal, MD, MBA, the U...
AI in Radiology: Enhancing Analysis, Education, and Access
24 May 2024
Contributed by Lukas
Can AI augment radiological processes, imaging analysis, and diagnosis? In this Q&A, Saurabh Jha, MBBS, MRCS, MS, an associate professor of radiology ...
Enhancing Global Mental Health Care With Digital Tools and AI for Scalable Interventions
03 May 2024
Contributed by Lukas
Can AI/machine learning-driven digital phenotyping facilitate global personalized medicine? In this Q&A, Vikram Patel, MBBS, PhD, the Paul Farmer Prof...
Using AI to Increase Access to Reliable Health Information
05 Apr 2024
Contributed by Lukas
Could generative AI assist in extending access to vulnerable populations and begin to bridge the gap in disparities? In this Q&A, Davey Smith, MD, MAS...
The Potential for AI to Enable Speech and Facilitate Full Expression for Individuals With Brain Injuries
22 Mar 2024
Contributed by Lukas
AI can understand brain signals linked to the sensory and motor processes involved in speech. In this Q&A, Edward Chang, MD, the chair and professor o...
How AI Could Advance Human Heart Discoveries and Improve Care
06 Mar 2024
Contributed by Lukas
Can AI enhance the speed and efficiency of interpreting ultrasounds and echocardiograms, thereby minimizing diagnostic errors? In this Q&A, Rima Arnao...
Automation Bias and Short Cuts in Clinical AI Models
28 Feb 2024
Contributed by Lukas
Automation bias and shortcuts in clinical AI models have posed significant challenges. In this Q&A, Jenna Wiens, PhD, an associate professor of Comput...
AI and the Ethics of Developing and Deploying Clinical AI Models
07 Feb 2024
Contributed by Lukas
AI in clinical practice needs ethical frameworks to avert future biases. In this Q&A, Marzyeh Ghassemi, PhD, the Herman L. F. von Helmholtz Career Dev...
Discovery and Scaling Findings From Large, Multicenter Health Care Datasets
24 Jan 2024
Contributed by Lukas
How can we leverage AI to transform health care into a more efficient model for delivering care? In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Dom...
AI Monitoring to Reduce Data-Based Disparities
03 Jan 2024
Contributed by Lukas
Amid the surging buzz around artificial intelligence (AI), can we trust the Al hype, and more importantly, are we ready for its implications? In this ...
AI Guardrails: The US Executive Order and the Need for Global Harmonization
20 Dec 2023
Contributed by Lukas
Artificial intelligence holds the promise of revolutionizing disease diagnosis and prediction, but it also presents a pivotal challenge: ensuring equi...
The AI Health Care Goal for Patient Care
13 Dec 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews John Ayers, PhD, MA, vice chief of innovation in the Division of I...
The Learning Health System and AI
15 Nov 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Nigam Shah, MBBS, PhD, professor of medicine at Stanford Universit...
Predictive AI and Early Clinical Detection
01 Nov 2023
Contributed by Lukas
AI has potential to meaningfully improve patient care. How will AI advances help clinicians focus on the best use of their time and talents? In this Q...
Can AI Accelerate Medical Education?
25 Oct 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Bernard S. Chang, MD, MMSc, a neurologist and dean for medical education ...
Building Patient and Clinician Trust in a Health Care System
18 Oct 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, talks with Andrew Bindman, MD, an internist and the executive vice president ...
Improving Health Care Quality and Equity
11 Oct 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Kedar S. Mate, MD, an internal medicine physician, President and ...
The Potential to Reduce Clinician Burden and Streamline Health Systems
04 Oct 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Kevin B. Johnson, MD, MS, the David L. Cohen and Penn Integrates Knowledg...
The Potential for AI to Augment Humanity in Medicine
27 Sep 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Ida Sim, MD, PhD, a primary care physician and UCSF's Chief Research Info...
AI Gaslighting, AI Hallucinations, and GenAI Potential
20 Sep 2023
Contributed by Lukas
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Michael Howell, MD, MPH, a pulmonologist and chief clinical office...