JAMA Clinical Reviews
Episodes
Adverse Pregnancy Outcomes and Long-term Health Risks
19 Apr 2022
Contributed by Lukas
After certain adverse pregnancy outcomes, an individual's risk for cardiovascular and other diseases increases. JAMA Associate Editor Linda Brubaker, ...
A Review of Pulmonary Arterial Hypertension
12 Apr 2022
Contributed by Lukas
Pulmonary arterial hypertension is a rare condition that requires a thorough workup to evaluate for potential causes and right heart catheterization f...
Epilepsy Diagnosis and Treatment in Adults
05 Apr 2022
Contributed by Lukas
Epilepsy affects approximately 65 million people worldwide and is associated with increased rates of bodily injuries and mortality when not optimally ...
Acute Cholecystitis
08 Mar 2022
Contributed by Lukas
More than 200 000 individuals in the US develop acute cholecystitis annually. The majority of these cases are caused by gallstones blocking the cystic...
Thrombolytics and Endovascular Thrombectomy for Acute Ischemic Stroke
01 Mar 2022
Contributed by Lukas
Treatment strategies for acute ischemic stroke are continuing to evolve. JAMA Associate Editor and vascular neurologist Jeffrey Saver, MD, from the Un...
COVID-19 and Pregnancy: Disease Outcomes and Prevention With Vaccination
22 Feb 2022
Contributed by Lukas
Pregnant and recently pregnant individuals who become infected with the COVID-19 virus are at high risk of requiring extra medical care. JAMA Associat...
Diagnosis and Treatment of Acute Coronary Syndromes
15 Feb 2022
Contributed by Lukas
Acute coronary syndromes are characterized by a sudden reduction in blood supply to the heart, and the syndromes include ST-segment elevation myocardi...
Treatment of Tobacco Smoking
08 Feb 2022
Contributed by Lukas
Tobacco smoking is responsible for more deaths in the US each year than any other preventable cause of mortality. Approximately 14% of US adults smoke...
Diagnosis and Management of Multiple Myeloma
01 Feb 2022
Contributed by Lukas
Multiple myeloma is a hematologic malignancy characterized by abnormal plasma cells in the bone marrow, with potential uncontrolled growth causing des...
Diagnosis and Treatment of Sexually Transmitted Infections
25 Jan 2022
Contributed by Lukas
Approximately 1 in 5 adults in the US had a sexually transmitted infection in 2018. Khalil Ghanem, MD, PhD, of Johns Hopkins University joins JAMA Dep...
Evaluation and Management of Patients With Pulmonary Nodules
18 Jan 2022
Contributed by Lukas
Pulmonary nodules are commonly found on lung imaging studies. Evaluation and management depends on the size and other characteristics of pulmonary nod...
Evaluating the Results of Platform Clinical Trials: A Guide for Clinicians
04 Jan 2022
Contributed by Lukas
The last few years have seen a tremendous increase in the conduct of platform clinical trials, a type of randomized clinical trial that can simultaneo...
Contraceptive Selection: Incorporating Patient Health, Values, and Preferences
28 Dec 2021
Contributed by Lukas
Approximately 87% of US women will use contraception during their lifetime. Stephanie Teal, MD, MPH, from University Hospitals Cleveland Medical Cente...
Medication Safety During Pregnancy
21 Dec 2021
Contributed by Lukas
Nearly all pregnant individuals use at least 1 medication, either prescribed or over-the-counter, during their pregnancy. Denise Jamieson, MD, MPH, pr...
Current Management of Acute Appendicitis: Antibiotics or Surgical Intervention
14 Dec 2021
Contributed by Lukas
Appendectomy remains the first-line therapy for acute appendicitis, but treatment with antibiotics rather than surgery is appropriate in selected pati...
Management of Acne Vulgaris
23 Nov 2021
Contributed by Lukas
Acne vulgaris is one of the most common skin disorders seen in the outpatient clinic setting. Lawrence F. Eichenfield, MD, of the University of Califo...
Evaluation of Iron Deficiency Anemia
26 Oct 2021
Contributed by Lukas
Iron deficiency anemia can be caused by either decreased iron availability or increased iron requirements after blood loss from the gastrointestinal (...
How to Interpret and Use a Clinical Practice Guideline
19 Oct 2021
Contributed by Lukas
Romina Brignardello-Petersen, DDS, PhD, and Gordon Guyatt, MD, of McMaster University talk with JAMA Executive Deputy Editor Robert Golub, MD, about h...
Care and Treatment of Women After Surgical Menopause
12 Oct 2021
Contributed by Lukas
Bilateral salpingo-oophorectomy (BSO) causes premature menopause in younger women and is associated with reduced quality of life and cardiovascular, n...
Will This Patient Be Difficult to Intubate? A Rational Clinical Examination Review
21 Sep 2021
Contributed by Lukas
Recognizing a potentially difficult intubation can help clinicians prepare for complications by getting assistance from colleagues with airway trainin...
Managing Fluids in Critically Ill Patients
07 Sep 2021
Contributed by Lukas
Critically ill patients often require IV fluids for resuscitation but questions remain about the optimal type of IV fluid and best rate of IV fluid bo...
USPSTF Recommendation: Screening for Prediabetes and Type 2 Diabetes
24 Aug 2021
Contributed by Lukas
Interview with Chien-Wen Tseng, MD, USPSTF member and coauthor of Screening for Prediabetes and Type 2 Diabetes: US Preventive Services Task Force Rec...
USPSTF Recommendation: Screening for Gestational Diabetes
10 Aug 2021
Contributed by Lukas
Interview with Chien-Wen Tseng, MD, USPSTF member and coauthor of Screening for Gestational Diabetes Related Content: USPSTF Review: Screening for Ge...
Cost-effectiveness Analysis for Clinicians
05 Aug 2021
Contributed by Lukas
Cost-effectiveness analysis defines trade-offs between costs, harms, and benefits of alternative treatments and combines them into a single metric, th...
FDA Regulation and Approval of Medical Devices
03 Aug 2021
Contributed by Lukas
Rules for the regulation of medical devices, such as hip prostheses and implantable defibrillators, are complex and differ from those for drugs. Aaron...
Anabolic Therapy for Osteoporosis
27 Jul 2021
Contributed by Lukas
Anabolic drugs activate osteoblasts and are an alternative to bisphosphonates for treating osteoporosis. Kristine Ensrud, MD, MPH, professor of medici...
Novel Lipid-Lowering Therapies to Reduce Cardiovascular Risk
20 Jul 2021
Contributed by Lukas
Several new therapeutic drug classes are now available to manage lipid levels. John Wilkins, MD, MS, and Donald Lloyd-Jones, MD, ScM, of the Departmen...
Diagnosis and Treatment of Alcohol-Associated Liver Disease
13 Jul 2021
Contributed by Lukas
Alcoholic liver disease is increasing in incidence, especially in younger age groups. Ashwani Singal, MD, MS, professor of medicine at University of S...
Diagnosis and Treatment of Infertility
06 Jul 2021
Contributed by Lukas
Approximately 1 in 8 women of reproductive age seek treatment for infertility. JAMA Associate Editor Linda Brubaker, MD, joins Sandra Ann Carson, MD, ...
Transcatheter Treatments of Valvular Heart Disease
22 Jun 2021
Contributed by Lukas
Transcatheter valve repair has emerged as an important therapeutic option for patients with aortic and mitral valve disease. JAMA Deputy Editor Gregor...
Diagnosis and Clinical Care of Women With Chronic Pelvic Pain
15 Jun 2021
Contributed by Lukas
Chronic pelvic pain is a challenging condition that affects an estimated 26% of the world's female population. JAMA Associate Editor Linda Brubaker, M...
General Health Checks in Adult Primary Care
08 Jun 2021
Contributed by Lukas
Routine wellness or "checkup" visits are popular with patients and physicians but questions persist about their value, goals, and effective components...
Lower Extremity Peripheral Artery Disease Without Chronic Limb-Threatening Ischemia
01 Jun 2021
Contributed by Lukas
Lower extremity peripheral artery disease (PAD) affects approximately 8.5 million people in the US and about 230 million worldwide. JAMA Deputy Editor...
USPSTF Recommendation: Behavioral Counseling Interventions for Healthy Weight and Weight Gain in Pregnancy
25 May 2021
Contributed by Lukas
Interview with Aaron B. Caughey, MD, PhD, USPSTF member and coauthor of Behavioral Counseling Interventions for Healthy Weight and Weight Gain in Pre...
USPSTF Recommendation: Screening for Colorectal Cancer
18 May 2021
Contributed by Lukas
Interview with Michael Barry, MD, USPSTF vice chairperson and author of Screening for Colorectal Cancer: US Preventive Services Task Force Recommendat...
Diagnosis and Management of Headache, Part 2
13 May 2021
Contributed by Lukas
Headache disorders are one of the most common reasons patients visit emergency rooms and medical offices. Matthew S. Robbins, MD, associate professor ...
Diagnosis and Management of Headache, Part 1
11 May 2021
Contributed by Lukas
Headache is one of the most common reasons patients visit emergency rooms and medical offices. Matthew S. Robbins, MD, associate professor of neurolog...
Chronic Stable Angina—Diagnosis and Treatment
04 May 2021
Contributed by Lukas
Chronic stable angina reduces quality of life and only rarely leads to acute coronary syndrome (ACS). Treatment is lifestyle modification to manage at...
USPSTF Recommendation: Screening for Hypertension in Adults
27 Apr 2021
Contributed by Lukas
Interview with John B. Wong, MD, USPSTF member and coauthor of USPSTF Recommendation: Screening for Hypertension in Adults Related Content: Screenin...
Dual Antiplatelet Therapy After Acute Coronary Syndrome
20 Apr 2021
Contributed by Lukas
Dual antiplatelet therapy, typically aspirin and an oral P2Y12 receptor inhibitor (clopidogrel, prasugrel, ticagrelor, cangrelor), reduces adverse eve...
Space Travel and Human Health, Part 2
13 Apr 2021
Contributed by Lukas
Interest in space travel has increased since SpaceX's first commercial launch to the International Space Station (ISS) in May 2020 and with efforts to...
Space Travel and Human Health, Part 1
06 Apr 2021
Contributed by Lukas
Interest in space travel has increased since SpaceX's first commercial launch to the International Space Station in May 2020 and with efforts to send ...
Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke
01 Apr 2021
Contributed by Lukas
Shyam Prabhakaran, MD, chairman of neurology at the University of Chicago, discusses the diagnosis and evaluation of patients who present with transie...
Semaglutide for Weight Loss
23 Mar 2021
Contributed by Lukas
Semaglutide has recently been shown to induce clinically significant weight loss in patients with obesity that is sustained for as long as the drug is...
A Simple Way to Understand Statistical Multiple Comparison Procedures
09 Mar 2021
Contributed by Lukas
Performing repeated statistical comparisons on data can result in false-positive findings. Jing Cao, PhD, associate professor of statistics at Souther...
Irritable Bowel Syndrome—Diagnosis and Treatment
02 Mar 2021
Contributed by Lukas
Irritable bowel syndrome (IBS) is a clinical syndrome of vague abdominal pain and cramping associated with diarrhea or constipation. IBS is a diagnosi...
Advance Directives
26 Feb 2021
Contributed by Lukas
Advance directives (ADs) allow patients to express their medical treatment preferences. Patients with ADs are more likely to receive medical care conc...
Coronavirus Vaccines—An Overview
26 Feb 2021
Contributed by Lukas
The Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines are the first of many being tested for widespread use. Buddy Creech, MD, MPH, director of the V...
Vaccinating Nursing Home and Long-term Care Facility Residents for Coronavirus
24 Feb 2021
Contributed by Lukas
The CDC coordinated a massive effort to immunize nearly all nursing home and long-term care facility residents in the US against COVID-19 infection in...
Diagnosis and Treatment of Multiple Sclerosis—A Review
23 Feb 2021
Contributed by Lukas
Highly effective B-cell therapies like rituximab and ofatumumab have changed the outlook for patients with multiple sclerosis (MS). Alexander Rae-Gran...
Structural Racism for Doctors—What Is It?
23 Feb 2021
Contributed by Lukas
This is Dr Howard Bauchner, Editor in Chief of JAMA and the JAMA Network. The podcast on structural racism based on the discussion between Dr Ed Livin...
Mask Wearing for COVID-19 Prevention—Summary of CDC Data
10 Feb 2021
Contributed by Lukas
Natural experiments comparing coronavirus spread on ships and in hair salons with vs without face masks point to the importance of wearing masks for c...
Osteoarthritis—Diagnosis and Treatment
09 Feb 2021
Contributed by Lukas
Philip Cohen, MD, associate clinical professor of internal medicine at UCLA, a primary care internist who also specializes in sports medicine, discuss...
Management of Immunotherapy-Related Toxicities
02 Feb 2021
Contributed by Lukas
Immune checkpoint inhibitors have been a major breakthrough in cancer treatment but can have many serious adverse effects. Pankti Reid, MD, MPH, assis...
Acute Pancreatitis Part 2 of 2: Treatment
26 Jan 2021
Contributed by Lukas
Howard Reber, MD, emeritus professor of surgery at UCLA, discusses how to treat acute pancreatitis. Related Article(s): Acute Pancreatitis
Acute Pancreatitis Part 1 of 2: Diagnosis
26 Jan 2021
Contributed by Lukas
Howard Reber, MD, emeritus professor of surgery at UCLA, discusses how to diagnose acute pancreatitis. Related Article(s): Acute Pancreatitis
Racial and Ethnic Disparities in COVID-19
22 Jan 2021
Contributed by Lukas
Ethnic and racial minorities have been particularly hard hit with COVID-19 in some communities. Mitchell Katz, MD, president and chief executive offic...
Pharmacologic Management of Tobacco Cessation
19 Jan 2021
Contributed by Lukas
Tobacco use is the leading cause of preventable disease and death in the world, but most attempts to quit are unsuccessful. Atul Jain, MD, assistant p...
The Winter COVID-19 Surge in New York and Los Angeles
15 Jan 2021
Contributed by Lukas
Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, di...
Glaucoma Diagnosis and Treatment
12 Jan 2021
Contributed by Lukas
Glaucoma is the most common cause of irreversible blindness in the world. Joshua Stein, MD, MS, associate professor of ophthalmology at the University...
Oral Antibiotics for Appendicitis
11 Jan 2021
Contributed by Lukas
A new trial reports that a third of emergency department patients presenting with appendicitis admitted for oral antibiotic treatment had outcomes no ...
Understanding the New SARS-CoV-2 Mutation Found in England
08 Jan 2021
Contributed by Lukas
Gregory Armstrong, MD, director of the Advanced Molecular Detection Program for the CDC, explains what is currently known about the new mutations of S...
Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice (Repost)
06 Jan 2021
Contributed by Lukas
Next-generation sequencing is a catchall term for new, high-throughput technologies that allow rapid sequencing of a full genome. It can be used to se...
COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions
06 Jan 2021
Contributed by Lukas
Tom Shimabukuro, MD, MPH, MBA, and Sara Mbaeyi, MD, MPH, from the CDC discuss rare allergic complications in patients who received the first dose of t...
Patent Foramen Ovale and Secondary Stroke Prevention
05 Jan 2021
Contributed by Lukas
Patent foramen ovale (PFO) is an often overlooked cause of acute ischemic stroke. JAMA Associate Editor Jeffrey Saver, MD, professor of neurology at U...
Crohn Disease Management
05 Jan 2021
Contributed by Lukas
New therapies have greatly improved outcomes for patients with Crohn disease. Peter Higgins, MD, from the University of Michigan, discusses advances i...
Understanding SARS-CoV-2 Genetic Variants
31 Dec 2020
Contributed by Lukas
Adam Lauring, MD, PhD, from the University of Michigan Division of Infectious Diseases, an expert on the evolutionary biology of RNA viruses, explains...
Nursing Homes and COVID-19
30 Dec 2020
Contributed by Lukas
Elderly persons and residents of nursing homes have been the hardest hit in the COVID-19 pandemic. Harvard geriatrician Sharon Inouye, MD, discusses t...
Managing Chronic Medical Conditions for Homeless Patients Presenting to the Emergency Department
22 Dec 2020
Contributed by Lukas
Homeless patients with chronic medical conditions who need long-term care often repeatedly present to emergency departments to receive treatment. Foll...
Parental Relationships with Children During COVID-19 Pandemic-Related Lockdowns
15 Dec 2020
Contributed by Lukas
JAMA Fishbein Fellow Kristin Walter, MD, interviews Craig Garfield, MD and Richard Weissbourd, EdD, about parental relationships during the COVID-19 p...
Gyms, Restaurants, Mass Transit, and Community COVID-19 Exposures
10 Dec 2020
Contributed by Lukas
Lockdowns resulting from COVID-19 have had a devastating effect on everyone's personal lives and the economy. What factors in people's daily lives are...
The Effect of Cannabis Intoxication on Driving Ability
08 Dec 2020
Contributed by Lukas
It is well known that alcohol use severely affects driving ability, but does cannabis? There are many fewer traffic crashes related to cannabis than a...
Air Handling Standards for Increasing the Safety of Indoor Spaces During the COVID-19 Pandemic
07 Dec 2020
Contributed by Lukas
Closing businesses during the COVID-19 pandemic has had devastating consequences for individuals and the economy in general. Proper air handling combi...
Understanding Permuted Blocks and Stratification in Randomized Clinical Trials
03 Dec 2020
Contributed by Lukas
Roger J. Lewis, MD, PhD, discusses Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods Related Article(s): Randomization i...
Hearing Loss in Children
01 Dec 2020
Contributed by Lukas
Judith Lieu, MD, from the Department of Otolaryngology–Head & Neck Surgery at Washington University in St Louis, discusses the need for screening yo...
Health Care Facility Certificate of Need Regulations—Laws That Have Outlived Their Usefulness
24 Nov 2020
Contributed by Lukas
Certificates of Need are regulations required by some states before any construction or expansion of services at medical facilities are undertaken. Or...
Hematuria and Bladder Cancer
17 Nov 2020
Contributed by Lukas
Mark Litwin, MD, chair of Urology at the UCLA School of Medicine, discusses the evaluation of hematuria and also the presentation, diagnosis, and trea...
Elevated Liver Function Tests Following Liver Transplant
10 Nov 2020
Contributed by Lukas
There are hundreds of thousands of liver transplant patients, all of whom will be seen in general clinical practices. It is common for them to develop...
Using e-Cigarettes to Stop Smoking
10 Nov 2020
Contributed by Lukas
Are e-cigarettes helpful or harmful as a tool to help people stop smoking? Mark J. Eisenberg, MD, MPH, from the Jewish General Hospital and McGill Uni...
New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy
06 Nov 2020
Contributed by Lukas
A new multisociety guideline was recently released suggesting that for many patients, the interval between colonoscopies following polyp resection is ...
The Effect of COVID-19 on the 2020-2021 Influenza Season
02 Nov 2020
Contributed by Lukas
Tim Uyeki, MD, chief medical officer for the Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Contro...
Ticagrelor or Clopidogrel for Antiplatelet Therapy After Percutaneous Intervention for Acute Coronary Syndrome?
27 Oct 2020
Contributed by Lukas
The Platelet Inhibition and Patient Outcomes (PLATO) trial showed that ticagrelor had better outcomes than clopidogrel for avoiding thrombotic complic...
Can We Count on Herd Immunity to Control COVID-19?
19 Oct 2020
Contributed by Lukas
Many people are hoping that enough people develop resistance to COVID-19, either from being exposed to the disease or from vaccination, to develop her...
Ten Things Every New Doctor Should Know About Drug Reactions
13 Oct 2020
Contributed by Lukas
David Juurlink, MD, PhD, a clinical pharmacologist and professor of internal medicine at Sunnybrook Health Sciences Centre and professor of medicine a...
Coping With Death
06 Oct 2020
Contributed by Lukas
One of the most important things clinicians can do is help patients and their families deal with impending death. Despite its importance, this part of...
Sweden and COVID-19
02 Oct 2020
Contributed by Lukas
Sweden's response to the COVID-19 pandemic differed from its neighbors in Europe. Lockdowns were minimized with the belief that they would be more dam...
Updated Guidelines for the Treatment of Community-Acquired Pneumonia
01 Oct 2020
Contributed by Lukas
In the 13 years since the American Thoracic Society and Infectious Diseases Society of America have issued guidelines for the treatment of community-a...
Intimate Partner Violence
22 Sep 2020
Contributed by Lukas
Intimate partner violence--also known as domestic abuse--may affect as many as 1 in 3 women. It's often underreported but that shouldn't be the case. ...
Failing the Boards—What Happens When the Board Fails Itself?
15 Sep 2020
Contributed by Lukas
When trying to administer its qualifying examination during the COVID-19 shutdowns, the American Board of Surgery failed. Jo Buyske, MD, president and...
Treating Obstructive Sleep Apnea
04 Sep 2020
Contributed by Lukas
A new clinical trial suggests that obstructive sleep apnea (in patients unable to tolerate treatment with CPAP or other devices) can be treated with a...
Understanding Stepped-Wedge Clinical Trials
03 Sep 2020
Contributed by Lukas
Cluster randomized trials are performed when an intervention must be delivered to a group of patients like when testing new nursing protocols on award...
What Is It Like to Have COVID-19?
01 Sep 2020
Contributed by Lukas
COVID-19 continues to rapidly spread throughout the world. In the past few months, the population affected by the disease has shifted from older to yo...
Update on Bariatric Surgery—2020
01 Sep 2020
Contributed by Lukas
Bariatric surgery is unequivocally the most effective means for inducing weight loss and managing diabetes for obese patients. There are numerous othe...
Update on Ulcerative Colitis—2020
27 Aug 2020
Contributed by Lukas
The new American College of Gastroenterology guideline on ulcerative colitis is discussed by one of its authors, David T. Rubin, MD, from the Inflamma...
Managing Acute Pancreatitis
25 Aug 2020
Contributed by Lukas
Acute pancreatitis can be a devastating disease. Complications of pancreatitis can be minimized by appropriate early, initial management. Joe Hines, M...
A Physician Gets Cancer
18 Aug 2020
Contributed by Lukas
Patients with serious disease fear the unknown. A physician with a serious disease knows the potential outcomes, making it far more difficult to cope....
The Consequences of Not Vaccinating for Measles
14 Aug 2020
Contributed by Lukas
Before COVID-19, even though most children got vaccinated for measles, too many did not, resulting in worsening outbreaks of measles. People forgot ho...
The Intersection Between Flu and COVID-19
14 Aug 2020
Contributed by Lukas
As the COVID-19 pandemic continues to spread throughout the world, flu season is almost upon us. This is concerning because there will be an overlap b...
How to Reopen Schools in the COVID-19 Era
13 Aug 2020
Contributed by Lukas
One of the most contentious issues relating to COVID-19 is when to reopen schools. This is a complicated matter because placing people in close quarte...
Why Are We Still Talking About Hydroxychloroquine as a Treatment for COVID-19?
13 Aug 2020
Contributed by Lukas
The use of hydroxychloroquine as a treatment for COVID-19 serves as an example of what is wrong with medical information being widely disseminated bef...