Longevity Roadmap

72: A Different Framework for Health?

26 Feb 2024

Contributed by Lukas

Buck Joffrey, MD interviews Anoop Kumar, MD on his perspective on health and wellness. Dr. Kumar is an emergency medicine doctor who is also knowledge...

71: Ask the Doctor 02/19

19 Feb 2024

Contributed by Lukas

In this episode, Buck addresses questions from listeners. Topics include: 00:34 What is a healthy range in your weight? 04:28 The dangerous kind of fa...

70: The Science Behind Music and Mental Health

12 Feb 2024

Contributed by Lukas

Buck Joffrey, MD interviews Dr. Daniel Bowling from Stanford University on the science behind music and mental health. Bowling discusses the fundamen...

69: Glutathione: The Master Antioxidant

05 Feb 2024

Contributed by Lukas

Buck Joffrey, MD welcomes pharmacist and glutathione expert Dr. Nayan Patel. This podcast discusses the role of glutathione as an antioxidant includin...

68: Food Allergy 101 with Tina Sindher, MD

29 Jan 2024

Contributed by Lukas

Buck welcomes Tina Sindher, a specialist in food allergy from Stanford University Medical Center to discuss the basics of food allergy. Topics includ...

67: The Silent Global Epidemic Killer

22 Jan 2024

Contributed by Lukas

Buck Joffrey, M.D. discusses metabolic syndrome which affects 1/4 of the global adult population and how it underlies the development of virtually eve...

66: What is the common cold and how do you treat it?

17 Jan 2024

Contributed by Lukas

Buck talks about the common cold. He discusses the etiology, the role of cold weather, prevention and treatment of this common and frustrating problem...

65: Aging Skin and How to Fight It

15 Jan 2024

Contributed by Lukas

Buck interviews Dr. Corey Frucht, MD, PhD, a board-certified dermatologist on the topic of aging skin and skin cancer. This episode explores the cause...

63: A Look Back at 2023

01 Jan 2024

Contributed by Lukas

In this special New Year episode, Buck reviews some of the concepts discussed on the show in 2023.  

62: Ask the Doctor 12/25

25 Dec 2023

Contributed by Lukas

In this episode, Buck addresses questions from listeners. Topics include oral hygiene, Alzheimer's disease, and Matthew Perry's ketamine-related death...

61: Wisdom Wednesday: Surviving vs Winning

20 Dec 2023

Contributed by Lukas

Buck talks about mindset and the self-inflicted limits of the "survivor."

60: Inflammaging

18 Dec 2023

Contributed by Lukas

Buck Joffrey, MD summarizes his literature search on what the data says in regards to the mechanisms by which the most common diseases of age such as ...

59: How Much Exercise Is Too Much For Longevity?

13 Dec 2023

Contributed by Lukas

In this brief video, Buck Joffrey discusses literature suggesting that there is a "Goldilocks" zone for exercising for longevity. He also talks about...

58: A Review on the Risks and Benefits of Human Growth Hormone Supplementation

11 Dec 2023

Contributed by Lukas

Buck reviews the physiology behind human growth, hormone in humans. He discusses normal growth hormone patterns as people age, pathologies and studies...

57: How Stress Impacts Your Body

06 Dec 2023

Contributed by Lukas

Stress is an unavoidable element in modern society. Inherently, We know it's bad for us. In this episode of Sapio, Buck looks at the scientific and me...

56. Ask the Doctor (December 2023)

04 Dec 2023

Contributed by Lukas

In this episode of Sapio with Buck Joffrey, Buck welcomes back Dr. Alan Viglione of Montecito Concierge Medicine. Dr. Viglone discuss several topics ...

55: Engaging Your Subconscious For Success

29 Nov 2023

Contributed by Lukas

In this episode of Sapio with Buck Joffrey, Buck discusses the importance of setting clear goals and truly believing they can be achieved. He emphasiz...

54: What Supplements Does Buck Take?

27 Nov 2023

Contributed by Lukas

In this episode of Sapio with Buck Joffrey, Buck reveals the supplements and drugs that he takes for the purpose of longevity.   In addition to provi...

53: How to Avoid Blood Clots During Holiday Travel

22 Nov 2023

Contributed by Lukas

Buck provides ways to prevent getting deep venous thrombosis during long flights and drives. Deep Venous thrombosis refers to clots in the deep veins ...

52: What You Need to Know About Protein and Longevity

20 Nov 2023

Contributed by Lukas

In this episode of Sapio, Buck drills down on the importance of adequate levels of protein in a diet designed for longevity. Buck talks about the conc...

51: Part 2: Alzheimers's Disease: Risk Factors, Prevention and Treatment

15 Nov 2023

Contributed by Lukas

In our last episode of Sapio with Buck Joffrey, Neurologist Dr. John Foley took us through the diagnosis and pathophysiology behind Alzheimer's diseas...

50: Part 1: Alzheimers's Disease: Risk Factors, Prevention and Treatment

13 Nov 2023

Contributed by Lukas

In the next two episodes of Sapio with Buck Joffrey, we are going to talk about Alzheimer's disease. If you have never seen someone progress through t...

49: 3 Eating Tips to Live Longer

08 Nov 2023

Contributed by Lukas

48: Living Longer for Busy People

06 Nov 2023

Contributed by Lukas

Buck discusses his new book, Living Longer for Busy People in a question/answer session with producer, Ben Hyatt.

47: Exercising for Longevity and More with Dr. Tom Walters | 2 of 2

01 Nov 2023

Contributed by Lukas

Sapio with Buck Joffrey Episode 47 is part 2 of a 2 part episode with Dr. Tom Walters, DPT, OCS. Tom is a Doctor of Physical Therapy, former Kinesiolo...

46: Exercising for Longevity and More with Dr. Tom Walters | 1 of 2

30 Oct 2023

Contributed by Lukas

Sapio with Buck Joffrey Episode 46 is part 1 of a 2 part episode with Dr. Tom Walters, DPT, OCS. Tom is a Doctor of Physical Therapy, former Kinesiolo...

45: WHEN to Sleep to Reduce Your Risk of Alzheimer's Disease

25 Oct 2023

Contributed by Lukas

It's not just how much you sleep but WHEN you sleep that can affect your chances of getting Alzheimer's Disease. Buck Explains.

44: This Old Gout Drug May Help You Live Longer

23 Oct 2023

Contributed by Lukas

In Episode 44 of Sapio with Buck Joffrey, Buck discusses research that shows this old drug can be repurposed to fight the number one killer.

43: Make This One Simple Change To Improve Your Sleep

18 Oct 2023

Contributed by Lukas

In this Medical Update, Buck talks about one quick thing you can do to significantly improve the quality of your sleep. It goes against what we've bee...

42: Ask The Doctor

16 Oct 2023

Contributed by Lukas

In our latest "Ask The Doctor" episode, Dr. Alan Viglione joins Buck for a conversation that includes how to find a doctor that's right for you, the p...

41: FDA Panel: Popular Cold Medicine Doesn't Work

11 Oct 2023

Contributed by Lukas

In this medical update Buck discusses news from the FDA about some of the most popular drugs at your pharmacy. Buck also discusses some alternatives t...

40: Full Body MRI: Avoiding Health Time Bombs

09 Oct 2023

Contributed by Lukas

In this Sapio with Buck Joffrey episode Buck talks to Dr. Sean London from Prenuvo. A company revolutionizing healthcare with it's full body MRI scans...

39: Tipping the Scales: A Closer Look at Wegovy & Ozempic for Weight Loss

04 Oct 2023

Contributed by Lukas

🎧 Dive deep into the world of weight loss solutions in this eye-opening episode of Sapio with Buck Joffrey. As the buzz around Wegovy and Ozempic i...

38: What is your TRUE age? Biological VS Chronological

02 Oct 2023

Contributed by Lukas

In this Sapio with Buck Joffrey Episode Short, Buck discusses Biological Age and how it is different than Chronological Age. Which of the two should b...

37: Psilocybin: Evidence that a Psychedelic May Treat Depression

27 Sep 2023

Contributed by Lukas

In this Sapio with Buck Joffrey Medical Update, Buck discusses depression and the psychedelics being used to treat it including Psilocybin and Ketamin...

36: Cold Therapy: Real Science or Cool Trend?

25 Sep 2023

Contributed by Lukas

🎧 New Episode of Sapio with Buck Joffrey: The world is buzzing about the benefits of cold therapy, but is it all it's cracked up to be? 🧊 Buck d...

35: Is Hearing Loss Connected to Dementia?

20 Sep 2023

Contributed by Lukas

In this Sapio with Buck Joffrey Medical Update, Buck discusses new reasearch that connects hearing loss and dementia. If you or a loved one is sufferi...

34: Female Sexual Dysfunction

18 Sep 2023

Contributed by Lukas

In this episode of Sapio with Buck Joffrey Dr. Duncan Turner joins Buck for a conversation on women's health, sexual dysfunction and what can be done ...

33: The Cutting Edge Science of Age Reversal - Part 2

13 Sep 2023

Contributed by Lukas

The exploration into the secrets of aging continues in this much-anticipated second part of our conversation with Dr. Joel Rothman from UCSB's Center ...

32: The Cutting Edge Science of Age Reversal - Part 1

11 Sep 2023

Contributed by Lukas

In this can't-miss episode, Buck engages in a riveting conversation with the Dr. Joel Rothman, the Founding Director at UCSB's Center for Aging and Lo...

31: What Covid does to your Brain

06 Sep 2023

Contributed by Lukas

Episode 31 of Sapio with Buck Joffrey discusses "What Covid does to your Brain". In this short episode Buck discusses his personal experience and the ...

30: What's Your Risk of Getting Alzheimer's Disease?

04 Sep 2023

Contributed by Lukas

In this episode of Sapio with Buck Joffrey, Buck discusses a new study out of Oxford that outlines 11 key risk factors for dementia. And the good news...

29: Male Sexual Health - Part 2

30 Aug 2023

Contributed by Lukas

In part 2 of this 2 part episode Buck discusses male sexual health with Justin Houman, MD from Tower Urology in Los Angeles. Over half of American men...

28: Male Sexual Health - Part 1

28 Aug 2023

Contributed by Lukas

In this two part episode Buck discusses male sexual health with Justin Houman, MD from Tower Urology in Los Angeles. Over half of American men over th...

27: Yamanaka Factors - Can Aging Be Reversed?

23 Aug 2023

Contributed by Lukas

Buck discusses Yamanaka Factors and recent experiments where a team led by David Sinclair was successful in reversing cellular age applying the concep...

26: Ask The Doctor P2 of 2

21 Aug 2023

Contributed by Lukas

In this edition of Ask The Doctor Executive Producer asks Buck viewer questions and some of his own. Discussed is continuous glucose monitoring for no...

25: Heart Rate Variability (HRV)

16 Aug 2023

Contributed by Lukas

Buck discusses Heart Rate Variability (HRV). What is it? Why does it matter and how can it effect your overall health in this mini Sapio with Buck Jof...

24: Ask The Doctor P1 of 2

14 Aug 2023

Contributed by Lukas

In this edition of Ask The Doctor Executive Producer asks Buck viewer questions and some of his own. Discussed is continuous glucose monitoring for no...

23: Jet Lag and Melatonin

09 Aug 2023

Contributed by Lukas

Planning a trip? Jet lag can be a serious impediment to making the most of it. Buck discusses jet lag; what it is and strategies to beat it including ...

22: Battle of Cardio IQs Part 2

07 Aug 2023

Contributed by Lukas

Buck and Alan Viglione, MD discuss the Cardio IQ® report in detail and battle it out to see has the best numbers in this 2 part episode. This is Part...

21: Why Did Bronny James Collapse?

02 Aug 2023

Contributed by Lukas

Scary news last week when Bronny James, the 18 year old son of Lebron and Savannah James collapsed during a workout at USC. It has been reported that ...

20: Battle of Cardio IQs Part 1

31 Jul 2023

Contributed by Lukas

Buck and Alan Viglione, MD discuss the Cardio IQ® report in detail and battle it out to see has the best numbers in this 2 part episode. Part 2 will ...

19: Snoring and Sleep Apnea: Just Noise or Silent Killers?

26 Jul 2023

Contributed by Lukas

In this episode Buck discusses snoring and sleep apnea and why they should be taken seriously. 0:01:17 - Snoring And Sleep Apnea 0:01:45 - Up To 20% ...

18: Could This Simple Blood Test Revolutionize Early Cancer Detection?

24 Jul 2023

Contributed by Lukas

Buck talks with GRAIL President Josh Ofman, MD, MSHS, about their groundbreaking Multi-cancer early detection (MCED) technology and it's promise as a ...

17: Is Your Diet Coke Killing You?

19 Jul 2023

Contributed by Lukas

In this Sapio Short Buck discusses the news last week that the World Health Organization (WHO) has declared the artificial sweetener Aspartame a "a po...

16: Ask the Doctor

17 Jul 2023

Contributed by Lukas

In this episode, Alan Viglione, MD joins Buck to answer some of our audience questions. 0:01:08 - How To Prevent The Dawn Phenomenon Or Rise Of Sugar...

15: Essentials of Female Hormone Replacement

13 Jul 2023

Contributed by Lukas

In this episode Buck continues his conversation with Rob Hamilton MD from Prestige Regenerative Medicine - this time discussing Female Hormone Replace...

14: Essentials of Male Hormone Replacement

12 Jul 2023

Contributed by Lukas

Buck discusses Male Hormone Replacement with Rob Hamilton, MD from Prestige Regenerative Medicine. When to get it, why to get it, what to expect and h...

13: Reprogramming Your Brain with Ketamine and Psychedelics: Part 2

05 Jul 2023

Contributed by Lukas

In part two of a two part episode Buck talks with Dr. Michael Mantz, MD about Ketamine and Psychedlics. 0:00:29 - What Is Psilocybin? 0:01:42 - The S...

12: Reprogramming Your Brain with Ketamine and Psychedelics: Part 1

04 Jul 2023

Contributed by Lukas

In this is a two part episode Buck talks with Dr. Michael Mantz, MD about Ketamine and Psychedlics. Part 2 will be online for our regular Wednesday ep...

11: Fountain of Youth or Just a Dry Sauna?

28 Jun 2023

Contributed by Lukas

Buck discusses studies on the effect of saunas for overall health and longevity. 0:01:35 - What's The Big Deal With Saunas? 0:02:03 - Kuopio Ischemic...

10: Longevity Pillar 6: Being Social Helps You Live Longer

26 Jun 2023

Contributed by Lukas

Buck and Montecito Concierge Medicine's Alan Viglione explore compelling studies revealing the profound impact of social connections on our longevity....

9: Taurine: An Ingredient in Energy Drinks that May Add Years to Your Life!

21 Jun 2023

Contributed by Lukas

Buck discusses with Executive Producer Ben Hyatt a study that appeared June 9th, 2023 in Science magazine that linked Taurine with healthy aging and i...

8: Longevity Pillar 5: Personalized Diagnostics to Monitor Your Own Health

19 Jun 2023

Contributed by Lukas

Shownotes: 1:02 What is Diagnostics when it comes to medicine? 2:35 What are some of the traditional Diagnostics used in Medicine 2.0? 4:11 - Summari...

7: Metformin: Miracle Longevity Drug or Hype?

15 Jun 2023

Contributed by Lukas

Shownotes: 0:01:04 Metformin and Diabetes 0:02:48 Metformin Monotherapy 0:06:46 Are There Any Geroprotective Benefits From Taking Metformin? 0:10:50 ...

6: Longevity Pillar 4: Taking Drugs That Can Help You Live Longer

12 Jun 2023

Contributed by Lukas

Shownotes: 0:01:54 Geroprotective Medication 0:09:51 Addressing Fear Of Medication 0:12:22 Preventing Cardiovascular Disease 0:15:27 PCSK9 Inhibitors...

5: Longevity Pillar 3: Sleeping to Live Longer and Healthier

05 Jun 2023

Contributed by Lukas

Shownotes: 0:01:31 The Importance Of Sleep For Health 0:03:41 Rapid Eye Movement (REM) Sleep 0:03:57 Non-REM Sleep 0:06:22 Sleep Problems and Links t...

4: Longevity Pillar 2: Exercise THE RIGHT WAY!

29 May 2023

Contributed by Lukas

Our understanding of how to get the most out of exercise has evolved. A combination of cardio training with weight training can have a profound effect...

3: Why Hyperglycemia is a KILLER (and what to do about it)

26 May 2023

Contributed by Lukas

In this bonus Q&A episode Buck Joffrey dives a little deaper into one of the key Episode 2 topics - blood glucose and how it affects your body with Sa...

2: Longevity Pillar 1: What to Eat and When

20 May 2023

Contributed by Lukas

There is more to healthy eating than calories in and calories out. Learn the new science around eating to extend life including what to eat and when! ...

1: An Introduction to Sapio

19 May 2023

Contributed by Lukas

An Introduction to the pillars on longevity and underlying science. Buck talks with Montecito Concierge Medicine's Alan Viglione. Shownotes: 0:00:31 ...