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Mayo Clinic Pharmacy Grand Rounds

Activity Overview

Episode publication activity over the past year

Episodes

Statin’ the Facts for HIV Heart Health: Insights from the REPRIEVE Study

18 Dec 2024

Contributed by Lukas

Damon Alvarez, PharmD, MBA provides insights on statin use in people living with HIV.   For more pharmacy content, follow Mayo Clinic Pharmacy Reside...

The B1 and Only: Evaluation of Thiamine in Septic Shock

11 Dec 2024

Contributed by Lukas

Kennedy Concannon, PharmD discusses the use of thiamine in septic shock.   For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs ...

Mu’tually Beneficial? Buprenorphine Induction Strategies for OUD

04 Dec 2024

Contributed by Lukas

Katie Bye, PharmD shares insights on buprenorphine induction strategies for opioid use disorders.   For more pharmacy content, follow Mayo Clinic Pha...

Antidotes or Ambiguity? Understanding the use of uridine triacetate and glucarpidase in chemotherapy toxicity.

27 Nov 2024

Contributed by Lukas

Brandy Hernandez, PharmD shares nuances on the use of uridine triacetate and glucarpidase in chemotherapy toxicity management   For more pharmacy con...

Too Much Pressure? Non-Selective Beta-Blocker Use in Portal Hypertension

20 Nov 2024

Contributed by Lukas

Taylor Gullickson, PharmD educates on the use of beta-blockers in portal hypertension   For more pharmacy content, follow Mayo Clinic Pharmacy Reside...

Get the Knack for NAC: Management of Acetaminophen Overdoses

13 Nov 2024

Contributed by Lukas

Megan Edwards, PharmD discusses optimal management of acetaminophen overdose.   For more pharmacy content, follow Mayo Clinic Pharmacy Residency Prog...

Throm-B-Gone: Optimizing the Timing of Anticoagulation After Stroke Secondary to Atrial Fibrillation

06 Nov 2024

Contributed by Lukas

Micaela Warfield, PharmD shares updates on the timing of anticoagulation following stroke secondary to atrial fibrillation.   For more pharmacy conte...

Time to be Suc-SYNCytial: Managing Respiratory Syncytial Virus in HSCT Patients

30 Oct 2024

Contributed by Lukas

Jake Noble, PharmD, MPH reviews management of respiratory syncytial virus in patients undergoing allogeneic hematopoietic stem cell transplant.   For...

To Hold or Not to Hold? The Use of Metformin with Contrast Media Inpatient and Incretin Mimetics Perioperatively

23 Oct 2024

Contributed by Lukas

Caitlin Schanz, PharmD & Krysta Larson, PharmD review metformin use inpatient and incretin mimetic use perioperatively.   For more pharmacy conte...

Aminoglycosides and MT-RNR1: a Drug-Gene Interaction You May Not Have Heard About

16 Oct 2024

Contributed by Lukas

Alex McCarthy, PharmD, MS discusses aminoglycoside induced hearing loss and genetic testing.   For more pharmacy content, follow Mayo Clinic Pharmacy...

Extending Compassion Through Expanded Access to Investigational Medicine

09 Oct 2024

Contributed by Lukas

Trinkal Patel, PharmD shares insights on compassionate use and investigational medicine.   For more pharmacy content, follow Mayo Clinic Pharmacy Res...

A Whole LADA Mystery: Uncovering Latent Autoimmune Diabetes in Adults

02 Oct 2024

Contributed by Lukas

Krista Olson, PharmD reviews pharmacotherapeutic approaches to latent autoimmune diabetes in adults.   For more pharmacy content, follow Mayo Clinic ...

Interoperability: When devices have a conversation

25 Sep 2024

Contributed by Lukas

Sherwyn Tenia, PharmD, MBA, BCPS, PMP explores interoperability with a focus on smart infusion pumps.   For more pharmacy content, follow Mayo Clinic...

Feeling a Bit Psor? Pharmacological Treatment Options in Psoriasis

18 Sep 2024

Contributed by Lukas

Nate Johnson, PharmD, BCPS discusses updates in the pharmacologic treatment for psoriasis.   For more pharmacy content, follow Mayo Clinic Pharmacy R...

Beyond Dispensing: Pioneering the Future of Pharmacy Services

10 Jul 2024

Contributed by Lukas

Mark Layden discusses pharmacy quality outcomes, metrics, and the future direction of justifying clinical pharmacy services.   For more pharmacy cont...

Breaking it Down: Pseudomonas aeruginosa Resistance

03 Jul 2024

Contributed by Lukas

Jenna Jackson we will review mechanisms of resistance, management of multidrug resistant infections, and antimicrobial development.   For more pharma...

Scratching the Itch: The Role of the Pharmacist in De-Labeling Antimicrobial Agents

26 Jun 2024

Contributed by Lukas

Matt Neumann, PharmD outlines recommendations to manage patients with penicillin and other antimicrobial allergy labels.   For more pharmacy content,...

Is Rate Control the Rate-limiting Step in Management of Atrial Fibrillation? Rate versus Rhythm Control with a Focus on Antiarrhythmic Drugs

19 Jun 2024

Contributed by Lukas

Alyssa Pitterle, PharmD compares rate and rhythm control in the management of atrial fibrillation with a focus on pharmacotherapy.    For more pharm...

When is Seizure Prophylaxis Indicated in Traumatic Brain Injury: Seizing the Opportunity

12 Jun 2024

Contributed by Lukas

Lauren Metropulos, PharmD will review seizure prophylaxis in traumatic brain injury.   For more pharmacy content, follow Mayo Clinic Pharmacy Residen...

Get Psyched: Legislative Approval of Medical Psychedelics and their Implications

05 Jun 2024

Contributed by Lukas

Natalie Hagy, PharmD, discusses medical use of psychedelics, including legislative and practical considerations for states and hospitals   For more p...

Tirzepatide: Weighing the Options

29 May 2024

Contributed by Lukas

Mickenzie Meyers, PharmD shares insights on pharmacotherapeutic approaches to weight loss.   For more pharmacy content, follow Mayo Clinic Pharmacy R...

Going Against the Graine: Triptans and Cardiovascular Disease

22 May 2024

Contributed by Lukas

Jordyn Erkel, PharmD reviews the connection between migraines and cardiovascular disease. For more pharmacy content, follow Mayo Clinic Pharmacy Resid...

A Brighter Future: Exploring the Role of Brentuximab vedotin in Pediatric Hodgkin’s Lymphoma

15 May 2024

Contributed by Lukas

Taylor Gullickson, PharmD explores the role of brentuximab vedotin in pediatric Hodgkin’s lymphoma. For more pharmacy content, follow Mayo Clinic Ph...

Transplanting New Ideas: Updates in Cytomegalovirus Prophylaxis Solid Organ Transplantation

08 May 2024

Contributed by Lukas

Kennedy Concannon, PharmD discusses cytomegalovirus prophylaxis in solid organ transplantation. For more pharmacy content, follow Mayo Clinic Pharmacy...

Infusion Confusion: Defining the Role of Prolonged Infusion Beta-Lactams

13 Mar 2024

Contributed by Lukas

Micaela Warfield, PharmD evaluates the role of prolonged infusion of beta-lactam antibiotics. For more pharmacy content, follow Mayo Clinic Pharmacy R...

Breathing New Life into COPD Exacerbation Management

06 Mar 2024

Contributed by Lukas

Katie Bye, PharmD provides insights on the management of COPD exacerbations. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs...

Pumping Iron: IV Iron Replacement in HFrEF

28 Feb 2024

Contributed by Lukas

Will Carns, PharmD reviews the role of intravenous iron in the treatment of heart failure with reduced ejection fraction. For more pharmacy content, f...

Buprenorphine for Opioid Use Disorders: Should you Stop Periop?

21 Feb 2024

Contributed by Lukas

Julia Branger, PharmD discusses use of buprenorphine in the perioperative period. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Pro...

Infectious Risk with Advanced Therapies in Inflammatory Bowel Disease

14 Feb 2024

Contributed by Lukas

Megan Edwards, PharmD shares insights on navigating infection risk with advanced therapies for inflammatory bowel disease. For more pharmacy content, ...

Starving for Answers: Parenteral Nutrition in the Critically Ill

07 Feb 2024

Contributed by Lukas

Brandy Hernandez, PharmD reviews approaches to nutritional need assessment in critical care. For more pharmacy content, follow Mayo Clinic Pharmacy Re...

Statin Intolerance and Clear Alternatives

31 Jan 2024

Contributed by Lukas

Andrea Aguayo, PharmD provides insights on statin intolerance and alternative approaches. For more pharmacy content, follow Mayo Clinic Pharmacy Resid...

Nirsevimab: Prevent RSV or Let it Be?

24 Jan 2024

Contributed by Lukas

Kimberly James, PharmD shares developments on respiratory syncytial virus (RSV) prevention in infants. For more pharmacy content, follow Mayo Clinic P...

Starting off STRONG: Optimizing Heart Failure Treatment at Transitions of Care

17 Jan 2024

Contributed by Lukas

Krysta Larson, PharmD provides updates on heart failure treatment strategies in transitions of care. For more pharmacy content, follow Mayo Clinic Pha...

When Drugs BITE Back: Managing Toxicities of Bispecific T-Cell Engagers

10 Jan 2024

Contributed by Lukas

Jenna Puttkamer, PharmD shares insights into toxicity management of bispecific t-cell engagers. For more pharmacy content, follow Mayo Clinic Pharmacy...

Colchi(seen) to Reduce Cardiovascular Risk in Established ASCVD

13 Dec 2023

Contributed by Lukas

Maggie Ruschmeyer, PharmD reviews the evidence in colchicine for secondary prevention of ASCVD. For more pharmacy content, follow Mayo Clinic Pharmacy...

It’s Not All Negative: Antibody Drug Conjugates in HER-2 Low Breast Cancer

06 Dec 2023

Contributed by Lukas

Brianna Chambers, PharmD describes the landscape for HER-2 low classification in the treatment of breast cancer. For more pharmacy content, follow May...

The Intensive Approach: Updates for Blood Pressure Control in Intracerebral Hemorrhage

29 Nov 2023

Contributed by Lukas

Allie Curran, PharmD reviews blood pressure management strategies in intracerebral hemorrhage. For more pharmacy content, follow Mayo Clinic Pharmacy ...

My, Oh, Myocarditis: More to Monitor for Clozapine?

15 Nov 2023

Contributed by Lukas

Caitlin Schanz, PharmD discusses considerations for clozapine-induced myocarditis. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Pr...

Going Viral! Reactivation of Viral Infections Following Cancer Treatment

08 Nov 2023

Contributed by Lukas

Abdullah Al-Ajmi, PharmD, BCPS reviews approaches to viral reactivation following cancer treatment. For more pharmacy content, follow Mayo Clinic Phar...

Don’t Lose Your Nerve: Supporting the Denervated Heart after Cardiac Transplantation

01 Nov 2023

Contributed by Lukas

Tanner Melton, PharmD reviews pharmacologic management of post cardiac transplant. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Pr...

Shocking Update: The Use of Fludrocortisone in Septic Shock

25 Oct 2023

Contributed by Lukas

Hailey Thompson, PharmD shares SHOCKing updates on the use of corticosteroids in septic shock. For more pharmacy content, follow Mayo Clinic Pharmacy ...

Bad Blood: Anemia Management Updates in the Setting of Chronic Kidney Disease

18 Oct 2023

Contributed by Lukas

Mark Layden, PharmD, MBA shares the place in therapy for hypoxia-inducible factor prolyl hydroxylase inhibitors and other general approaches to anemia...

A Rumble in the Fungal Jungle: Review of the New Antifungal Agents

11 Oct 2023

Contributed by Lukas

Natalie T. Hagy, PharmD shares new antifungal agents in the pipeline, their novel mechanisms of action, and available formulations. For more pharmacy ...

Lost in the ECMO Chamber: Pharmacokinetics in Critical Illness

04 Oct 2023

Contributed by Lukas

Ming May Zhang, PharmD reviews pharmacokinetic considerations in extracorporeal membrane oxygenation. For more pharmacy content, follow Mayo Clinic Ph...

Must be mAb on the Brain: A New Hope for Alzheimer’s Disease

13 Sep 2023

Contributed by Lukas

Hailey Thompson, PharmD, reviews primary literature and shares updates on the role of monoclonal antibody therapies in the treatment of Alzheimer’s ...

GPS for APS: Navigating Anticoagulation in Antiphospholipid Syndrome

06 Sep 2023

Contributed by Lukas

Caitlin Schanz, PharmD discusses antiphospholipid syndrome, with a focus on data comparing direct oral anticoagulants versus warfarin as anticoagulati...

Waving Goodbye to the X Waiver: Reassessing Medication Treatment for Opioid Use Disorder

30 Aug 2023

Contributed by Lukas

Tanner Melton, PharmD reviews literature on buprenorphine and methadone in treating opioid use disorder. For more pharmacy content, follow Mayo Clinic...

Give it a Shot! Long-Acting Injectables in HIV Therapy

23 Aug 2023

Contributed by Lukas

Christopher Cahoon, PharmD elucidates the literature pertaining to injectable cabotegravir and rilpivirine as HIV therapy options. For more pharmacy c...

Taking the LEAD? Dual Pathway Inhibition Therapy for Lower Extremity Arterial Disease

16 Aug 2023

Contributed by Lukas

Shienna Braga, PharmD examines the literature pertaining to dual pathway inhibition for lower extremity arterial disease. For more pharmacy content, f...

What’s Been ‘Flozin On: Updates in Outpatient Management of Chronic Kidney Disease

09 Aug 2023

Contributed by Lukas

Lauren Stonerock, PharmD describes updates in outpatient management of chronic kidney disease. For more pharmacy content, follow Mayo Clinic Pharmacy ...

Celebrating diversity: challenges and strategies to promote pharmacogenomics translation across populations

02 Aug 2023

Contributed by Lukas

Serena Mitaly, PharmD shares strategies for pharmacogenomic research translation to reduce health disparities. For more pharmacy content, follow Mayo ...

What’s the Best for CRS?

26 Jul 2023

Contributed by Lukas

Devon Stonerock, PharmD, Uzo Abajue, PharmD and Divya Khandekar, PharmD describe cytokine release syndrome (CRS), the literature surrounding CRS and o...

Pitter Patter, Let’s Get ATTR: Medications for Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

19 Jul 2023

Contributed by Lukas

Kelli Herrin, PharmD reviews the pathophysiology of transthyretin amyloidosis cardiomyopathy and provides updates on medication options.   For more p...

Updates on the Clozapine REMS Program: An Important Relic or Fool’s Gold of Safety?

12 Jul 2023

Contributed by Lukas

Jonathan Leung, PharmD, BCPS, BCPP provides updates on the clozapine REMS program, reviews the therapeutic benefits of clozapine, as well as key adver...

On Another Level: The Role of Therapeutic Drug Monitoring in Inflammatory Bowel Disease

05 Jul 2023

Contributed by Lukas

Sarah A. Chase, PharmD reviews the pathophysiology and current treatment strategies for inflammatory bowel disease, defines the clinical application o...

All-In on Insulin? Use of High-Dose Insulin Euglycemic Therapy in Calcium Channel Blocker Overdose

28 Jun 2023

Contributed by Lukas

Kyle A. Hess, PharmD, BCPS Twitter: @KyleHessPharmD describes the pathophysiology of calcium channel blocker overdose, explains the rationale for use ...

Measuring Value in Drug Therapy

21 Jun 2023

Contributed by Lukas

Scott A. Soefje, PharmD, MBA, BCOP, FCCP, FHOPA (Twitter: @sasoefje) describes the relationship between value and quality, defines quality and how qua...

Verification Decision Support: May AI Take Your Order?

14 Jun 2023

Contributed by Lukas

Benjamin J. Anderson, PharmD, MPH, FASHP and Diana J. Schreier, PharmD, MBA, BCPS recognize the history and regulations for prospective medication ord...

A Hard-Pressed Debate: The Role of Terlipressin in Hepatorenal Syndrome

07 Jun 2023

Contributed by Lukas

Nikitha Yagnala, PharmD and Andy J. Jatis, PharmD, BCPS describe the pathophysiology of hepatorenal syndrome (HRS), describe the pathophysiology of he...

Freezing Ethylene Glycol Toxicity

31 May 2023

Contributed by Lukas

Kamryn R. Storm, PharmD (Twitter @KRStorm) outlines the mechanism of toxicity for ethylene glycol, identifies clinical findings of ethylene glycol tox...

Emerging Antibiotics – Tetra(cycle)ine Back to Basics

24 May 2023

Contributed by Lukas

Ashton C. Praska, PharmD (Twitter @ashpraka) describes tetracycline resistance mechanisms utilized by bacteria, identifies how Omadacycline/Eravacycli...

Pharmacotherapy for the Treatment of Obesity

17 May 2023

Contributed by Lukas

Kristina M. Thurber, PharmD, BCPS recognizes pharmacotherapy for the treatment of obesity and explain mechanisms of action for each class, discusses a...

Off the Chain: The Drug Supply Chain and Medication Shortages

10 May 2023

Contributed by Lukas

Jo Ann Leal, PharmD (Twitter @JoJoPharmD) describes the key components of the drug supply chain and the impact of drug shortages, identifies common or...

Clostridioides difficile Infection: Do We C the Diff-erence in Preventing Recurrence?

03 May 2023

Contributed by Lukas

Andrew (Andy) F. Wiener, PharmD (Twtitter @andywiener) describes the pathogenesis and risk factors of C. diff infection and recurrence, reviews the pr...

Pharmacologic Treatment of Drug Resistant Hypercholesterolemia

26 Apr 2023

Contributed by Lukas

Seth M. Kriha, PharmD identifies guideline recommended treatment to reduce LDL-C, evaluates landmark clinical trials for novel therapeutic agents indi...

It’s Going Tibia Okay: Supportive Bone Health in Oncology

05 Apr 2023

Contributed by Lukas

Christopher R. Cahoon, PharmD defines the importance of optimizing bone health in patients with bone metastases and lytic lesions, describes preferred...

Preserving the Future: Fertility Preservation in Cancer Patients

29 Mar 2023

Contributed by Lukas

Shienna A. Braga, PharmD explains the effects of select chemotherapeutic agents on gonadal function and fertility in cancer patients, recognizes the d...

SUPPosed SUPPort: Targeted Review of Supplements Recommended in Clinical Practice

22 Mar 2023

Contributed by Lukas

Linda Huang, Pharm.D identifies considerations for use of select provider-recommended supplements, describes literature that helps explain use of sele...

Bridging the Gap: Controversies in Perioperative Anticoagulation Management

15 Mar 2023

Contributed by Lukas

Ming May Zhang, PharmD (Twitter: @amayzhanggg) reviews key bleeding and thromboembolic risks that should be considered in the perioperative setting, d...

To Measure or Not to Measure? Prophylactic Enoxaparin Management in Trauma Patients

08 Mar 2023

Contributed by Lukas

Hailey A. Thompson, PharmD identifies the physiologic factors that increase venous thromboembolism risk in trauma patients, outlines current recommend...

Put on Your Thinking CAP: Steroid Use in Community-Acquired Pneumonia?

01 Mar 2023

Contributed by Lukas

Caitlin C. Schanz, PharmD (@Schanz_Caitlin) explains the pharmacological mechanism of steroid use in community-acquired pneumonia treatment, interpret...

When the CAR-T’s Over: Managing the Long-Term Complications of CAR-T Therapy

22 Feb 2023

Contributed by Lukas

Alejandro Del Rio Verduzco, PharmD (Twitter: @Alejandro_DRV) defines the different short-term and long-term toxicities of CAR-T therapy, describes evi...

“Seeing R.E.D” Racial and Ethnic Disparities in Cardiovascular Disease State Medication

15 Feb 2023

Contributed by Lukas

Aleesha Jantzen, PharmD describes social determinants of health that impact management of cardiovascular disease states, recognizes racial/ethnic disp...

Nobody Likes Rejection: Therapeutic Drug Monitoring of Mycophenolate in Solid Organ Transplant

08 Feb 2023

Contributed by Lukas

Tanner A. Melton, PharmD (Twitter @TAMeltonRx) reviews factors associated with inter- and intra-patient mycophenolate pharmacokinetic variability, des...

Ascorbic Acid Episode IV: The Rise and Fall of Vitamin C

01 Feb 2023

Contributed by Lukas

Mark P. Layden, PharmD, MBA (Twitter @Layden_Rx) describes the pathophysiology of sepsis and role of Vitamin C in the critically ill population, ident...

Turning the Page on the Monoamine Story: Utilizing the NMDA Pathway for Major Depressive Disorder

25 Jan 2023

Contributed by Lukas

Natalie T. Hagy, PharmD describes the monoamine and glutaminergic pathway for the treatment of major depressive disorder, recognizes response and remi...

Pump It Up: An Overview of Diabetic Insulin Pumps

18 Jan 2023

Contributed by Lukas

Lauren R. Stonerock, PharmD (@LStonerockRx) reviews the history of insulin delivery technology and its impact on diabetes management, identifies patie...

“Rheum” for Improvement: Review of Rheumatoid Arthritis Treatment Guidelines

11 Jan 2023

Contributed by Lukas

Chelsea M. Morken, PharmD (@ChelseaMorken) explains the pathophysiology of rheumatoid arthritis (RA), describes the literature regarding cardiovascula...

Don’t You Know that You’re Toxic? Cardiotoxicity Prevention and Treatment in Oncology

04 Jan 2023

Contributed by Lukas

Uzoamaka (Uzo) C. Abajue, PharmD (@Uzo_Chi) discusses the manifestations, diagnosis, and classification of chemotherapy induced cardiotoxicity, identi...

Mab Scientists: Therapeutic Drug Monitoring with Eculizumab

28 Dec 2022

Contributed by Lukas

Megan A. Galle, PharmD (@meganciclovir) reviews eculizumab’s mechanism of action and its role in treating antibody mediated rejection following soli...

Pharmacy’s Fantastic when the Marrows Aplastic: Pharmacologic Management of Aplastic Anemia

21 Dec 2022

Contributed by Lukas

Devon S. Stonerock, PharmD (@DevonStoneRx) describes the underlying pathophysiology driving the development and progression of aplastic anemia, outlin...

It’s in the Genes: Identification and Treatment of ESBL-E

14 Dec 2022

Contributed by Lukas

Sarah A. Chase, PharmD identifies the most common ESBL-producing bacteria and common ESBL resistance genes, recognizes the use and limitations in usin...

Early Multimodal Vasopressors in Septic Shock: When is it Time for Full-Court Press(ors)?

07 Dec 2022

Contributed by Lukas

Kyle A. Hess, PharmD (@KyleHessPHarmD) describes the rationale for early use of vasopressors with multiple mechanisms of action in patients with septi...

The R(igh)T Way or the Highway: Pharmacologic Management of Radiation Therapy (RT) Toxicities

30 Nov 2022

Contributed by Lukas

Divya A. Khandekar, PharmD, MS (@pharmdiv) discusses the basic principles of radiation therapy in the treatment of cancer, describes the etiology and ...

The Unit that Never Sleeps: Pharmacologic Sleep Agents for Critically Ill Patients

23 Nov 2022

Contributed by Lukas

Nikitha Yagnala, PharmD (@nikithayagnala) recognizes the physiologic consequences of sleep disturbances in critically ill patients, discusses the mech...

Fluid Stewardship in the ICU: The Rush to De-resuscitate

16 Nov 2022

Contributed by Lukas

Andrew J. Jatis, PharmD (Twittter:@jatis_rx) Identifies adverse consequences of fluid overload in critically ill patients, summarizes literature asses...

A CYmPle Matter – CYP2C19 Polymorphisms and P2Y12 Inhibitor Selection in Ischemic Stroke

09 Nov 2022

Contributed by Lukas

Jo Ann Leal, PharmD (Twitter: @jojopharmd) describes the implications of various CYP2C19 phenotypes on clopidogrel metabolism and activity, analyzes t...

Pediatric Updates on Transplant Associated-Thrombotic Microangiopathy (TA-TMA)

19 Oct 2022

Contributed by Lukas

KaShena L. Kennedy, PharmD (Twitter: @KaShenaKennedy) reviews and identifies the pathophysiology, clinical manifestations, and diagnostic criteria for...

Time for a Heart-to-Heart: ADAPTing Antithrombotic Therapy Post-TAVR

12 Oct 2022

Contributed by Lukas

Aeryana Beaudrie-Nunn, PharmD (Twitter: @ABeaudrieRx) identifies the rationale for antithrombotic therapy following TAVR, reviews the utility of direc...

Dual Antiplatelet Therapy Following PCI: Choosing a SMART-DATE to STOP-DAPT

05 Oct 2022

Contributed by Lukas

Kyle A. Hess, PharmD (Twitter: @KyleHessPharmD ) describes current guideline recommendations for duration of dual antiplatelet therapy (DAPT) followin...

Level Up: Updates on Direct Oral Anticoagulant Plasma Levels

28 Sep 2022

Contributed by Lukas

Nikitha Yagnala, PharmD (Twitter: @NikithaYagnala) describes laboratory tests used to estimate DOAC plasma levels, reviews current literature explorin...

Is Shorter Better? Early Discontinuation of Empiric Antibiotics in Febrile Neutropenia

21 Sep 2022

Contributed by Lukas

Divya A. Khandekar, PharmD, MS (Twitter: @pharmdiv) describes the etiology of febrile neutropenia in patients with hematological malignancies, summari...

Long Acting Lipoglycopeptides: Antibiotic Friend or Foe?

14 Sep 2022

Contributed by Lukas

Andrew J. Jatis, PharmD (Twitter: @jatis_rx) reviews the pharmacology and drug characteristics of dalbavancin and oritavancin, describes current liter...

Strategies to Reduce Relapse after Hematopoietic Cell Transplantation

07 Sep 2022

Contributed by Lukas

Kaylee A. Clark, PharmD describes the basic principles of maintenance therapies after allogeneic HSCT, discusses evidence and guideline recommendation...

Process Management Techniques to Improve Patient Safety

31 Aug 2022

Contributed by Lukas

Kyle J. Eickman, PharmD, describe the goals of six sigma methodology and review examples of its application within pharmacy dispensing, reviews DMAIC ...

Let’s Take It One CYP At a Time: Unraveling the Role of CYP2B6 in Methadone Metabolism

24 Aug 2022

Contributed by Lukas

Dimple R. Dhakal, PharmD describes the pharmacodynamics and pharmacokinetics of methadone, identifies and discusses clinical practice guidelines for t...

Opioid Stewardship: A Focus on Opioids at Transitions of Care

17 Aug 2022

Contributed by Lukas

Julie L. Cunningham, PharmD, BCPP; M. Zeeshan Rizwan, PharmD, BCPS, BCCCP; Christi A. Jen, PharmD, BCPS, FASHP, FAzPA; and Kristina L. Wescott, PharmD...

When the Beat Drops: Pharmacotherapy in Cardiac Arrest

10 Aug 2022

Contributed by Lukas

Hannah M. Brokmeier, PharmD, describes the pathophysiology behind the pharmacologic targets in ACLS, discusses the role of vasopressin, steroids, and ...

To Augmentation and Beyond: Strategies for Treatment-Resistant Depression

27 Jul 2022

Contributed by Lukas

Lauren M. Dolly, PharmD, recalls the etiology and pathophysiology of TRD, discusses the role of pharmacogenomics in L-methylfolate for TRD, selects a ...

Oops! AI Did It Again!

20 Jul 2022

Contributed by Lukas

Pooja Ojha, PharmD, describes what bias in artificial intelligence entails, discusses implications of bias in artificial intelligence, evaluates mitig...