Neuroscience and Beyond

Decoding memory: plasticity, SUSHI and super-resolution microscopy with Prof. Valentin Nägerl

26 Feb 2024

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In this episode we speak with Prof. Valentin Nägerl, the head of the Synaptic plasticity and super-resolution microscopy group at the Interdisciplinary Institute for Neuroscience and Professor of Neuroscience and Bioimaging at the University of Bordeaux. Together, we delve into the intricacies of memory, demystifying terms like plasticity and synapses. Prof. Nägerl shares his knowledge about what is in between the neurons - the extracellular space. We continue with our recent theme of the super-resolution microscopy and explore another technique called SUSHI. The conversation extends to pressing topics like the reproducibility crisis and issues with the publishing system. Finally, we discuss the future of neuroscience.Our channel is supported by International Max Planck Research School (IMPRS) for Neurosciences as well as Cluster of Excellence Multiscale Bioimaging (MBExC) in Göttingen, Germany. The views presented on this channel are not representative of IMPRS or MBExC.Timestamps:00:00:00 Intro00:02:30 Early career and motivation for doing science00:05:43 What makes a research institution world-class?00:07:32 Establishing own research group in Bordeaux 00:09:08 Research focus: superresolution microscopy, synapses and plasticity00:13:39 Animal experiments in neuroscience00:19:43 Diversity of neurons and synapses00:20:42 Hippocampus, plasticity and memory00:30:23 STED microscopy and phototoxicity problem in live imaging00:40:35 Recording neural data from the awake animals00:42:43 SUSHI - super-resolution shadow imaging00:46:26 Studying extracellular space 00:56:26 Problems in academia: reproducibility crisis 01:01:30 Problems in academia: publishing system01:03:13 Work-life balance01:08:06 Future of neuroscienceFollow us on social media for the latest updates!Twitter: https://twitter.com/neuro_beyondInstagram: https://www.instagram.com/neurosciencebeyond/TikTok: https://www.tiktok.com/@neurosciencebeyondFacebook: https://www.facebook.com/neurosciencebeyondNeuroscience and Beyond team:Svilen GeorgievKristina Jevdokimenko

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13:00H | 21 DIC 2025 | Fin de Semana

01 Jan 1970

Fin de Semana

10:00H | 21 DIC 2025 | Fin de Semana

01 Jan 1970

Fin de Semana

12:00H | 20 DIC 2025 | Fin de Semana

01 Jan 1970

Fin de Semana

2ª PARTE | 06 ENE 2026 | EL PARTIDAZO DE COPE

01 Jan 1970

El Partidazo de COPE

3ª PARTE | 22 ENE 2026 | EL PARTIDAZO DE COPE

01 Jan 1970

El Partidazo de COPE

3ª PARTE | 04 MAR 2026 | EL PARTIDAZO DE COPE

01 Jan 1970

El Partidazo de COPE

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Neuroscience and Beyond

Decoding memory: plasticity, SUSHI and super-resolution microscopy with Prof. Valentin Nägerl

This episode hasn't been transcribed yet

Other recent transcribed episodes

13:00H | 21 DIC 2025 | Fin de Semana

10:00H | 21 DIC 2025 | Fin de Semana

12:00H | 20 DIC 2025 | Fin de Semana

2ª PARTE | 06 ENE 2026 | EL PARTIDAZO DE COPE

3ª PARTE | 22 ENE 2026 | EL PARTIDAZO DE COPE

3ª PARTE | 04 MAR 2026 | EL PARTIDAZO DE COPE

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