NIH Collaboratory
Episodes
Podcast 62: Ambient AI to Improve Health Practitioner Well-Being
30 Apr 2026
Contributed by Lukas
Majid Afshar and Mary Ryan Baumann discuss the conduct and results of their pragmatic trial.
Podcast 61: Evaluating Analytic Models for IRGT Trials
24 Mar 2026
Contributed by Lukas
Drs. Jonathan Moyer and David Murray discuss their recent publication, “Evaluating Analytic Models for Individually Randomized Group Treatment Trial...
Podcast 60: Virtual Vigilance in Decentralized Clinical Trials
18 Feb 2026
Contributed by Lukas
Drs. Adrian Hernandez and Christopher Lindsell discuss their recent publication, “Ensuring Virtual Vigilance in Decentralized Clinical Trials," as w...
Podcast 59: Gaps and Opportunities in America's Healthcare Landscape
16 Jan 2026
Contributed by Lukas
Dr. David Zaas discusses key takeaways from his recent keynote presentation: “Landscape of Healthcare in America: Gaps and Opportunities (That Resea...
Podcast 58: INSPIRE
18 Dec 2025
Contributed by Lukas
Drs. Shruti Gohil and Jeffrey Guy discuss key takeaways from "INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Pa...
Podcast 57: Integrating the BeatPain Study With PRaCTICe, a New Network Research Hub
26 Nov 2025
Contributed by Lukas
Drs. Sebastian Tong and Julie Fritz expand on key takeaways from their recent Grand Rounds presentation.
Podcast 56: "Avoiding the Fumble" in Pragmatic Clinical Trials
15 Oct 2025
Contributed by Lukas
Dr. Emily O'Brien shares key takeaways from her recent Grand Rounds presentation, "Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic...
Podcast 55: End-of-Trial Decision-Making
17 Sep 2025
Contributed by Lukas
Drs. Greg Simon and Lorella Palazzo discuss their recent Living Textbook Chapter, "End-of-Trial Decision-Making." Read the chapter: https://rethinkin...
Podcast 54: Disentangling Informing Participants From Obtaining Their Consent
12 Aug 2025
Contributed by Lukas
Drs. Pearl O'Rourke and David Wendler discuss their recent publication, "Disentangling Informing Participants From Obtaining Their Consent."
Podcast 53: Healthcare Data Interoperability and Standardization for Research
30 Jul 2025
Contributed by Lukas
Drs. Lesley Curtis and Keith Marsolo discuss the new learning module "Healthcare Data Interoperability and Standardization for Research."
Podcast 52: Making Pragmatic Trials More Pragmatic
24 Jun 2025
Contributed by Lukas
Drs. Rich Platt, Hayden Bosworth, and Greg Simon consider how to make pragmatic trials more pragmatic.
Podcast 51: ACP PEACE
16 May 2025
Contributed by Lukas
Dr. James Tulsky and Dr. Angelo Volandes discuss "Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly," also known as ...
Podcast 50: Waiver of Consent
11 Jul 2024
Contributed by Lukas
Dr. Pearl O'Rourke and Dr. Stephanie Morain discuss waiver or alteration of informed consent for minimal risk clinical investigations.
Podcast 49: Public-Private Partnerships in the Trustworthy Health AI Ecosystem
25 Jun 2024
Contributed by Lukas
Dr. Michael Pencina and Dr. Brian Anderson discuss Public-Private Partnerships in the Trustworthy Health AI Ecosystem.
Podcast 48: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial
01 Dec 2023
Contributed by Lukas
Dr. Harlan M. Krumholz and the PaxLC research team discuss Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial.
Podcast 47: BeatPain Utah
18 Jul 2023
Contributed by Lukas
Dr. Julie Fritz discusses "BeatPain Utah: Partnering with Community Health Centers Within a Socio-Technical Framework."
Podcast 46: All of Us Research Program
23 Jun 2023
Contributed by Lukas
Dr. Joshua Denny discusses the All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine.
Podcast 45: From Observational Studies to Pragmatic Clinical Trials: Research in PCORnet®
21 Apr 2023
Contributed by Lukas
Drs. Russell Rothman and Erin Holve discuss a decade of research in PCORnet®.
Podcast 44: The Heartline Trial: A New Paradigm in Conducting Virtual Clinical Trials
08 Mar 2023
Contributed by Lukas
Dr. Michael Gibson discusses The Heartline Trial and a new paradigm in conducting virtual clinical trials.
Podcast 43: Ethical Considerations for Vulnerable Populations in Pragmatic Clinical Trials
06 Feb 2023
Contributed by Lukas
This podcast continues the discussion with Dr. Emily Largent as she discusses ethical considerations for vulnerable populations participating in pragm...
Podcast 42: FDA Draft Guidance on Real-World Evidence
14 Jul 2022
Contributed by Lukas
Dr. John Concato discusses the 2021 FDA draft guidance on real-world evidence.
Podcast 41: Searching for a Unicorn: Selecting Outcomes for Outpatient Trials
25 Jan 2022
Contributed by Lukas
Dr. Christopher Lindsell discusses research outcomes and the importance of choosing the correct outcome.
Podcast 40: Survivor Corps: Long-Term COVID-19 Patient Engagement
16 Aug 2021
Contributed by Lukas
This podcast continues the discussion with Diana Berrent, JD, and Nick Guthe, founder and member of Survivor Corps, and Natalie Lambert, PhD, of the I...
Podcast 39: Inclusion of Diverse Participants in Pragmatic Clinical Trials
04 Aug 2021
Contributed by Lukas
Dr. Boineau moderates a discussion with Drs. Chambers, Curtis, O'Brien, Weber, and Zimmerman about increasing diverse participation in pragmatic clini...
Podcast 38: Online Recruitment in the Era of COVID-19: Pitfalls and Progress
01 Jun 2021
Contributed by Lukas
This podcast continues the discussion with Dr. Adrian Hernandez and Dr. Megan L. Ranney about using digital technologies in clinical trials and best p...
Podcast 37: Data and Safety Monitoring Boards for Trials of COVID-19 Vaccines: The Challenges
31 Mar 2021
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Susan Ellenberg of the University of Pennsylvania ...
Podcast 36: Beyond Politics: Promoting COVID Vaccination in the United States
03 Mar 2021
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Kevin Schulman of Stanford about strategies for pr...
Podcast 35: HERO-TOGETHER
21 Jan 2021
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Emily O'Brien of the Duke Clinical Research Instit...
Podcast 34: Lessons from Virtual Trials in Time of a Pandemic
12 Nov 2020
Contributed by Lukas
This podcast follows the conversation between Dr. David Boulware and Dr. Adrian Hernandez as they discuss the complexities of conducting virtual clini...
Podcast 33: The Democratization of Medicine
18 Aug 2020
Contributed by Lukas
This podcast follows the conversation between Dr. C. Michael Gibson and Dr. Adrian Hernandez as they discuss how open access, patient empowerment, soc...
Podcast 32: Reflection on Advances at the Intersection of Digital Health, EHRs, and PCTs
08 Jul 2020
Contributed by Lukas
This podcast, led by Wendy Weber, ND, PhD, MPH, features a reflective conversation with Lesley Curtis, PhD, Patrick Heagerty, PhD, and Keith Marsolo, ...
Podcast 31: Real World Evidence: Contemporary Experience and Future Directions
25 Jun 2020
Contributed by Lukas
This episode of the NIH Collaboratory Grand Rounds podcast follows the conversation on Electronic Health Records (EHRs) between Dr. Lesley Curtis and ...
Podcast 30: Can the COVID-19 Crisis Lead to Reformation of the Evidence Generation Ecosystem?
15 May 2020
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Lesley Curtis speaks with Dr. Robert Califf, Head of Strategy and Policy at Verily ...
Podcast 29: Creating a Learning Health System Through Randomization
20 Mar 2020
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Leora Horwitz of NYU Langone Health about creating...
Podcast 28: Using Nudges to Improve the Delivery of Health Care
20 Feb 2020
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Mitesh Patel of University of Pennsylvania about u...
Podcast 27: It’s Time to Learn From Patients Like Mine
12 Dec 2019
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Nigam Shah of Stanford University to discuss an...
Podcast 26: Playing with FHIR–Innovative Use Cases for the New REDCap EHR Integration Module
27 Nov 2019
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Paul Harris to discuss REDCap integration with ...
Podcast 25: Preparing for Clinical Trial Data Sharing and Re-use: The New Reality for Researchers
03 Oct 2019
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Drs. Rebecca Li and Frank Rockhold to discuss cli...
Podcast 24: Digital in Trials: Improving Participation and Enabling Novel Endpoints
21 Aug 2019
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Kevin Weinfurt sits down with Craig Lipset to discuss the role and impact of digi...
Grand Rounds August 2, 2019: AI and the Future of Psychiatry
07 Aug 2019
Contributed by Lukas
Dr. Murali Doraiswamy discusses potential uses of artificial intelligence technologies in the field of mental health. (Audio track of the webinar.)
Podcast 23: Good Clinical Practice Guidance & Pragmatic Trials in the Learning Health System
25 Jun 2019
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Rob Mentz to discuss balancing Good Clinical ...
Podcast 22: Development of Harmonized Outcome Measures for Use in Research and Clinical Practice
23 Apr 2019
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Elise Berliner and Michelle Leavy to discuss th...
Podcast 21: The Pragmatic Airway Resuscitation Trial (PART)
18 Feb 2019
Contributed by Lukas
Podcast 21: The Pragmatic Airway Resuscitation Trial (PART) by NIH Pragmatic Trials Collaboratory
Podcast 20: Perinatal Outcomes Associated with a Major Change in Gestational Diabetes Screening
28 Jan 2019
Contributed by Lukas
Podcast 20: Perinatal Outcomes Associated with a Major Change in Gestational Diabetes Screening by NIH Pragmatic Trials Collaboratory
Podcast 19: Validating a Computable Phenotype
05 Dec 2018
Contributed by Lukas
Podcast 19: Validating a Computable Phenotype by NIH Pragmatic Trials Collaboratory
Podcast 18: Data Linkage Within, Across, and Beyond PCORnet
19 Nov 2018
Contributed by Lukas
Podcast 18: Data Linkage Within, Across, and Beyond PCORnet by NIH Pragmatic Trials Collaboratory
Podcast 17: MDEpiNet RAPID and SPEED Projects
07 Nov 2018
Contributed by Lukas
Renee Mitchell, Terrie Reed, and Roseann White discuss the Medical Device Epidemiology Network’s RAPID and SPEED projects.
Podcast 16: Returning Individual Research Results to Participants
01 Oct 2018
Contributed by Lukas
Podcast 16: Returning Individual Research Results to Participants by NIH Pragmatic Trials Collaboratory
Podcast 15: Digital Pragmatic Clinical Trial for Identifying Underdiagnosed Atrial Fibrillation
07 Aug 2018
Contributed by Lukas
Steve Steinhubl, Director of Digital Media, Scripps RTI,discusses a digital & pragmatic clinical trial that explores under diagnosed Atrial Fibrillati...
Podcast 14: Clinical Trial Participants’ Views of the Risks and Benefits of Data Sharing
19 Jul 2018
Contributed by Lukas
In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Michelle Mello discusses a study she and Dr. Steven Goodman recently conducted to ...
Podcast 13: Rethinking University Research with State Data (Aaron McKethan, PhD)
10 Jul 2018
Contributed by Lukas
Podcast 13: Rethinking University Research with State Data (Aaron McKethan, PhD) by NIH Pragmatic Trials Collaboratory
Podcast 12: Exploring What is Possible with High-Quality Data. Examples from Flatiron Health
27 Jun 2018
Contributed by Lukas
Podcast 12: Exploring What is Possible with High-Quality Data. Examples from Flatiron Health by NIH Pragmatic Trials Collaboratory
Podcast 11: Launching NESTcc to Improve use of Real-World Evidence in Medical Device Ecosystem
21 May 2018
Contributed by Lukas
Podcast 11: Launching NESTcc to Improve use of Real-World Evidence in Medical Device Ecosystem by NIH Pragmatic Trials Collaboratory
Podcast 10: OHDSI: Drawing Reproducible Conclusions from Observational Clinical Data
16 Apr 2018
Contributed by Lukas
In this episode of the Collaboratory Grand Rounds podcast, Dr. George Hripcsak, Chair of the Bioinformatics Department at Columbia University, discuss...
Podcast 9: Data Science in the Era of Data Ubiquity
11 Apr 2018
Contributed by Lukas
Moderator Dr. Adrian Hernandez speaks with Duke Forge Director Dr. Robert Califf about the opportunities and challenges for data science in an era whe...
Podcast 8: Clinicians' Views on Participating in CER/PCOR
22 Mar 2018
Contributed by Lukas
Dr. Sean Tunis and Ellen Tambor discuss with moderator Dr. Kevin Weinfurt their findings on clinician attitudes towards research participation, and ho...
Podcast 7: Considerations for the Return of Genomic Results
19 Feb 2018
Contributed by Lukas
Dr. Andrew Faucett of Geisinger describes the considerations for the return of genomic results to patients.
Podcast 6: IMPACT-AFib: A Randomized Trial Using the Sentinel Initiative Platform
22 Jan 2018
Contributed by Lukas
Drs. Richard Platt and Christopher Granger speak with moderator Dr. Adrian Hernandez about the IMPACT-AFib atrial fibrillation trial and the role of t...
Podcast 1: Preprints: What, Why Not, and How
22 Jan 2018
Contributed by Lukas
Dr. Harlan Krumholz of Yale University Medical Center speaks with the NIH Collaboratory’s Dr. Adrian Hernandez about the ways preprint servers can h...
Podcast 5: Data and Safety Monitoring in Pragmatic Clinical Trials
03 Jan 2018
Contributed by Lukas
Dr. Greg Simon, principal investigator of the Suicide Prevention Outreach Trial (SPOT), and Susan Ellenberg, a member of the Collaboratory Regulatory/...
Podcast 4: Moderators' Edition
03 Jan 2018
Contributed by Lukas
Drs. Adrian Hernandez and Kevin Weinfurt, two NIH Collaboratory Co-PIs and podcast moderators, discuss their predictions and hopes for the NIH Collabo...
Podcast 3: Bringing Machine Learning to the Point of Care to Improve Suicide Prevention
03 Jan 2018
Contributed by Lukas
Dr. Greg Simon of the Kaiser Permanente Washington Health Research Institute speaks with the NIH Collaboratory’s Dr. Lesley Curtis about the integra...
Podcast 2: Health is More than Healthcare
03 Jan 2018
Contributed by Lukas
Dr. Karen DeSalvo, former acting Assistant Secretary for Health and Human Services, speaks with the NIH Collaboratory’s Dr. Kevin Weinfurt about the...