Retina Synthesis
Episodes
Assessment of Geographic Atrophy Lesion Progression in the Phase 3 Oaks and Derby Trials
13 Oct 2022
Contributed by Lukas
We review lesion progression in the eighteen month data with Roger Goldberg, MD, MBA of Bay Area Retina Associates, Walnut Creek, California.
The Role of the Clinician in Promoting Innovation
06 Oct 2022
Contributed by Lukas
We discuss the role that clinicians can play in fostering innovation in the retinal pharmacotherapy space with Dr. Eliot Lazar.
The DAVIO Study: 12 Month Results
22 Sep 2022
Contributed by Lukas
We discuss the 12 month results of the Phase I Davio Trial of an innovative TKI agent for the sustained treatment of neovascular AMD with Dr. Rishi Si...
Treat and Extend Therapy of Diabetic Macular Edema
15 Sep 2022
Contributed by Lukas
We discuss treat and extend versus alternate dosing strategies to treat center involving diabetic macular edema with Dr. Varun Chaudhary, Chief of Oph...
Prophylactic IOP Lowering Measures in Anti-VEGF Injections: A Meta-Analysis
08 Sep 2022
Contributed by Lukas
We discuss the role of IOP pressure elevation following intravitreal anti-VEGF therapy with Parnian Arjmand, MD, MSC, FCSRS of the Toronto Retina Inst...
Real World Efficacy, Durability and Safety of Faricimab
01 Sep 2022
Contributed by Lukas
We discuss real world experience about faricimab with Dr. Carl Danzig of Pompano Beach, Florida.
New Treatments for Radiation Retinopathy
25 Aug 2022
Contributed by Lukas
We discuss new treatment options and clinical trials for radiation retinopathy with Prithvi Mruthyunjaya MD Professor of Ophthalmology, Stanford Medic...
Gene Therapy of Inherited Retinal Diseases
18 Aug 2022
Contributed by Lukas
We discuss new developments in gene therapy for inherited retinal diseases with Sue Washer, President and CEO of AGTC.
RNA Anti Sense Therapy for Geographic Atrophy
11 Aug 2022
Contributed by Lukas
We discuss a novel strategy using RNA anti sense technology for treating geographic atrophy with Dr. Nik London, San Diego, California.
18 Month Results of the Derby and Oaks Trials for Treatment of Geographic Atrophy
04 Aug 2022
Contributed by Lukas
We discuss the 18 month results of the Derby and Oaks trials of pegcetacoplan for treatment of geographic atrophy with Roger Goldberg, MD of Walnut Cr...
A Novel Retinal Sealant
28 Jul 2022
Contributed by Lukas
We discuss a new retinal sealant that may replace the need for tamponade with expansile gas or silicone oil with Dr. James Anthony Stefater.
New Developments in Imaging and Therapy of Sickle Cell Retinopathy
21 Jul 2022
Contributed by Lukas
We discuss how new developments in imaging and therapeutics have impacted the treatment of sickle cell retinopathy with Dr. Adrienne Scott, Professor ...
High Dose (8mg) Aflibercept for Treatment of Neovascular AMD
07 Jul 2022
Contributed by Lukas
We discuss the results of a Phase II clinical trail studying the efficacy of high dose aflibercept (8mg) for treating neovascular AMD with Dr. David B...
New Developments in the Management of Choroidal Melanoma
30 Jun 2022
Contributed by Lukas
We discuss new developments in the diagnosis and therapy of choroidal melanoma with Dr. Paul Finger, Clinical Professor, NYU and Chair, Eye Cancer Fou...
A Stem Cell Implant for the Treatment of Geographic Atrophy
23 Jun 2022
Contributed by Lukas
We discuss the two year results of a Phase I/II trial of a stem cell implant for the treatment of geographic atrophy with Dr. Amir Kashani, Associat...
DERBY and OAKS Results
16 Jun 2022
Contributed by Lukas
We discuss the one year results of the DERBY and OAKs studies treating geographic atrophy with Dr. David Lally, Assistant Professor University of Ma...
Artificial Intelligence in the Management of Macular Degeneration
09 Jun 2022
Contributed by Lukas
We discuss the use of deep learning techniques in the detection and management of macular degeneration with Dr. Pearse Keane, Consultant Moorfields Ey...
An Oral Agent for the Treatment of Diabetic Retinopathy
02 Jun 2022
Contributed by Lukas
In our latest update, We discuss the use of APX3330 a novel oral agent for the treatment of diabetic retinopathy with Dr. David Boyer, Retina Vitreous...
Home OCT Monitoring of Neovascular AMD Treatment
26 May 2022
Contributed by Lukas
We discuss the use of a home based OCT system with artificial intelligence to monitor the treatment of neovascular AMD with Dr. Nancy Holekamp, Profes...
Faricimab in Diabetic Macular Edema: 2 Year Results of the RHINE and YOSEMITE studies
19 May 2022
Contributed by Lukas
We discuss the two year results of the first bispecific agent for the treatment of diabetic macular edema with Dr. John Wells III, from Palmetto Retin...
The Kingfisher Trial of Brolucizumab for DME
12 May 2022
Contributed by Lukas
We discuss the results of the Kingfisher trail, a study employing broluizumab q4 weeks for the treatment of diabetic macular edema with Dr. Mark Barak...
Subretinal Fluid in Neovascular AMD: Friend or Foe?
05 May 2022
Contributed by Lukas
We examine the role of sub retinal fluid in the treatment of neovascular AMD with Dr. David Sarraf, Professor of Ophthalmology, UCLA Stein Eye Institu...
Optogenetics
28 Apr 2022
Contributed by Lukas
We discussed and learned with Samarendra Mohanty, PhD: President and Founder of Nanoscope Technologies, about the fascinating science of vision restor...
Inhibition of Plasma Kallikrein in Diabetic Macular Edema
21 Apr 2022
Contributed by Lukas
We discuss a phase I study examining the effect of plasma kvllikrein inhibition on diabetic macular edema with Dr. Arshad Khanani, Sierra Eye Associat...
Neovascular AMD: Unpacking Surgical Disease Management Options
14 Apr 2022
Contributed by Lukas
Join these renowned experts for a panel discussion on how to incorporate into clinical practice the latest treatments for neovascular age-related macu...
Ocular Therapeutics Sustained Release TKI Trial
07 Apr 2022
Contributed by Lukas
We review the current status of the Ocular Therapeutics TKI sustained release delivery system for treatment of neovascular AMD with Dr. Andrew Moshfeg...
Gene Therapy of nAMD and Diabetic Retinopathy with Dr. Allen Ho
31 Mar 2022
Contributed by Lukas
We review current status of clinical research on gene therapy for neovascular AMD and diabetic retinopathy with Dr. Allen Ho, Professor of Ophthalmolo...
Long Term Results of the Port Delivery System
24 Mar 2022
Contributed by Lukas
We review long term results of the Port Delivery System for treating neovascular AMD with Dr. David Eichenbaum of Retina Vitreous Associates of Flor...
The Altissimo Study using a TKI for nAMD
17 Mar 2022
Contributed by Lukas
We review the results of the phase I Graybug study Altissimo using sustained release tyrosinase kinase inhibitor for long term treatment of neovascula...
The Paladin Study of the Fluocinolone Implant Treating Diabetic Macular Edema
10 Mar 2022
Contributed by Lukas
The fluocinolone implant at 3 years is a useful modality for treating diabetic macular edema. Discussion with Dr. Michael Singer, Adjunct Professor Un...
A Tyrosine Kinase Inhibitor that Successfully Treats nAMD
03 Mar 2022
Contributed by Lukas
We discuss the DAVIO trial of EYP-1901 with Dr. Jay S. Duker, Chief Operating Officer of Eyepoint Pharmaceuticals.
Late Breaking News on Kodiak Dazzle Trial
24 Feb 2022
Contributed by Lukas
We review the results of the KS-301 wet macular degeneration trial with Dr. Carl Regillo,Chief of the Retina Service at Wills Eye Hospital
Suprachoroidal Gene Therapy for Neovascular AMD
17 Feb 2022
Contributed by Lukas
Phase I results of suprachoroidal delivery of a gene vector in treating neovascular AMD are promising. A discussion with Nikolas London, MD from Ret...
Dosing with the Aflibercept Syringe
10 Feb 2022
Contributed by Lukas
Discussion of variations in injection volume for treatment of nAMD, DME and MERVO with Roger Goldberg, M.D., M.B.A., Bay Area Retina Associates
Results from the Hawk and Harrier Trials
03 Feb 2022
Contributed by Lukas
We examine the role of residual IRF and SRF in visual acuity results in treating nAMD. Dr. David Eichenbaum of Retina Vitreous Associates of Florida, ...
The Susvimo Sustained Delivery System for Neovascular AMD
27 Jan 2022
Contributed by Lukas
We discuss the use of the newly approved Susvimo system for sustained delivery of ranibizumab in the treatment of neovascular AMD with Carl Regillo, M...
The Basics of Suprachoroidal Drug Delivery
20 Jan 2022
Contributed by Lukas
We discuss the pathophysiology and techniques associated with subchoroidal administration of drugs and gene therapy vectors with James Major, MD, Ph.D...
Suprachoroidal Triamcinolone for Macular Edema: The Xipere System
05 Jan 2022
Contributed by Lukas
We discuss the newly approved Xipere system for suprachoroidal administration of triamcinolone for treatment of macular edema associated with uveitis ...
A Profile of Pravin Dugel, MD
20 Dec 2021
Contributed by Lukas
In our latest update, We discuss clinical and business careers with Pravin Dugel MD, President, of Iveric Bio.
Elamipretide for Treatment of Geographic Atrophy
29 Nov 2021
Contributed by Lukas
We discuss with David Lally, MD Springfield, Ma. Assistant Professor at University of Massachusetts and Tufts the use of elamipretide, a novel agen...
Stem Cells for the Treatment of Geographic Atrophy
22 Nov 2021
Contributed by Lukas
We discuss with Dr.Christoper Reimann of the Cincinnati Eye Institute the results of an early phase clinical trial in which stem cell derived retina p...
Suprachoroidal Gene Therapy for Diabetic Retinopathy
15 Nov 2021
Contributed by Lukas
We discuss the use of suprachoroidal gene therapy for eyes with diabetic retinopathy without macular edema with Dr. Dennis Marcus, Clinical Professor ...
Retinal Gene Therapy Surgical Techniques
08 Nov 2021
Contributed by Lukas
We review surgical techniques for sub retinal gene therapy with Dr. Lejla Vajzovic.
Management of Retinal Vein Occlusion
01 Nov 2021
Contributed by Lukas
Dr. Yasha Modi, Associate Professor of Ophthalmology at the NYU Langone Medical Center provides an evidence based review of management of retinal veno...
Cooling Anesthesia For Intravitreal Injection
24 Oct 2021
Contributed by Lukas
We discuss the use of a cooling probe as primary anesthesia for intravitreal injection with Ajay Kuriyan, MD, Associate Professor of Ophthalmology, Wi...
C1q Complement Blockade for Geographic Atrophy
11 Oct 2021
Contributed by Lukas
We discuss blockade of complement component C1q as a novel treatment for geographic atrophy with Donald Fong, MD, Vice President Ophthalmology Clinica...
CNTF Treatment of MacTel2
01 Oct 2021
Contributed by Lukas
We discuss clinical trials using CNTF to treat MacTel Type 2 with Dr. John Pollack, Chief Medical Officer of Neurotech Pharmaceuticals.
Optogenetic Therapy of Retinal Disease
21 Sep 2021
Contributed by Lukas
We asked Dr. Mohamed Genead, Chief Medical Officer, Nanoscope Therapeutics to discuss and review the latest developments in optogenetic gene therapy f...
Gene Therapy for Macular Neovascularization and Diabetic Retinopathy
08 Sep 2021
Contributed by Lukas
Dr. Robert Avery of California Retina Consultants reviews the latest status of gene therapy for AMD and DR.
Genetic Basis of Geographic Atrophy Treatment
02 Sep 2021
Contributed by Lukas
Many drugs are currently being investigated in attacking or supplementing the complement cascade for the treatment of geographic atrophy. We review, w...
Dr. Caroline Baumal with brolucizumab safety update.
16 Aug 2021
Contributed by Lukas
We interview Dr. Caroline Baumal, Professor Of Ophthalmology at New England Eye Center and the Tufts University School of Medicine and we review clini...
Augmented Reality in Retina
12 Aug 2021
Contributed by Lukas
Dr. Linda Lam, Professor of Ophthalmology at the USC Roski Eye Institute talks about augmented reality for low vision and unique surgical applications...
Focus on Samuel Barone, MD, CMO with Gemini Therapeutics
12 Jul 2021
Contributed by Lukas
Dr Barone describes the mission of Gemini and discusses recent preliminary data from the ongoing Phase 2a REGATTA study
Protocol W with Dr. Raj Maturi
15 Jun 2021
Contributed by Lukas
We knew that anti-VEGF therapy favorably affected the natural history of moderate or severe nonproliferation retinopathy. As a result of DRCR networ...
Update on the PANORAMA Trial
03 Jun 2021
Contributed by Lukas
Dr. Dilsher Dhoot discusses patient outcomes in the PANORAMA trial looking at areas of non perfusion.
A New Treatment Paradigm for Diabetic Macular Edema
27 Apr 2021
Contributed by Lukas
Dr. Jamie Dananberg, Chief Medical Officer of Unity Biotechnology discusses their strategy of selectively targeting senescent retinal vascular endothe...
Home OCT Monitoring of Anti-VEGF Therapy of Macular Neovascularization
15 Apr 2021
Contributed by Lukas
A Real World Clinical Trial Employing AIDr. Anat Loewenstein presents data demonstrating the effectiveness of the Notal Home OCT System with artificia...
Early Diagnosis of Macular Neovascularization
06 Apr 2021
Contributed by Lukas
Dr. Usha Chakravarthy, Professor of Ophthalmology, Queen's University Belfast presents characteristics of macular neovascularization at its earli...
Dr. Diana Do Discusses Kodiak KS-301 for nAMD, DME and RVO
01 Apr 2021
Contributed by Lukas
Diana Do, MD, Professor of Ophthalmology, Vice Chair Clinical Affairs, Department of Ophthalmology, Stanford University, Byers Eye Institute.
Focus on Dr. David Boyer of Retina Vitreous Associates Adjunct Professor, Keck School of Medicine of USC
07 Mar 2021
Contributed by Lukas
In this episode, Dr. David Boyer discusses a Phase 2 trial studying intravitreal injection of retinal progenitor cells for treatment of eyes with reti...
Focus on Cedric Francois, MD, PhD, CEO, Apellis Pharmaceuticals
07 Mar 2021
Contributed by Lukas
Dr. Francois discusses the epidemiology of geographic atrophy, the pathophysiology of complement inhibition in the treatment of GA, and the latest inf...
Dr. Charles Wykoff Interviews Karl Csaky MD, PhD Discussing Faricimab for DME and nAMD
07 Mar 2021
Contributed by Lukas
Join us in a discussion with Dr. Charles Wykoff & Karl Csaky MD, PhD on Faricimab for DME and nAMD. Interpreting the Durability Signals from the P...
Dr. Carmen Puliafito Interviews Charles Wykoff MD, PhD: Faricimab Results in DME & nAMD
07 Mar 2021
Contributed by Lukas
Join us as Dr. Carmen Puliafito and Charles Wykoff MD, PhD speak about the results. 1 of 3 total parts to "Interpreting Faricimab Phase 3 Data in...
Focus on Arshad Khanani MD, MA Director of Clinical Services Sierra Eye Associates
07 Mar 2021
Contributed by Lukas
Join us as Dr. Charles Wykoff dives in a discussion with Arshad Khanani MD, MA in a discussion on Faricimab in the TENAYA and LUCERN Phase 3 nAMD Tria...
Focus on Carl Regillo, MD, and PDS System
07 Mar 2021
Contributed by Lukas
Join us as Dr. Carmen Puliafito joins in a discussion with Carl Regillo, MD, Director of Retina Serivce, Wills Eye Institute on the topic of Phase 3 R...
Spotlight on Andrew Moshfeghi, MD, Associate Professor, USC Roski Eye Institute
07 Mar 2021
Contributed by Lukas
Dr. Carmen Puliafito interviews Andrew Moshfeghi, MD on a topic: Tyrosine Kinase Inhibitor Delivery by Hydrogel for Treatment of Wet AMD
Focus on Michael Goldstein , Chief Medical Officer at Ocular Therapeutix
06 Mar 2021
Contributed by Lukas
Michael Goldstein MD, MM Chief Medical Officer at Ocular Therapeutix also served as Co-Director, Cornea, External Disease and Cataract Service; Refrac...
Spotlight on David Zacks, M.D., Ph.D. Co-Founder and Chief Science Officer at ONL Therapeutics
06 Mar 2021
Contributed by Lukas
Spotlight on David Zacks, M.D., Ph.D. Co-Founder and Chief Science Officer at ONL Therapeutics.
Focus on Kourous Rezaei Chief Medical Officer at IVERIC bio
06 Mar 2021
Contributed by Lukas
Focus on Kourous Rezaei Chief Medical Officer at IVERIC bio in a discussion with Charles Wykoff.
Spotlight on Dr. Adam Rogers CEO of Hemera Biosciences
06 Mar 2021
Contributed by Lukas
Join Dr. Carmen Puliafito and Adam Rogers, MD in a discussion on Hemera Biosciences's approach in treating Geographic atrophy.
Dr. Philip Rosenfeld Looks at the Future of Macular Degeneration Part 2
05 Mar 2021
Contributed by Lukas
Dr. Philip Rosenfeld of the Bascom Palmer Eye Institute joins Dr. Charles Wykoff and Dr. Carmen Puliafito furthering questions about geographic atroph...
Dr. Philip Rosenfeld Looks at the Future of Macular Degeneration
05 Mar 2021
Contributed by Lukas
Dr. Philip Rosenfeld of the Bascom Palmer Eye Institute joins Dr. Charles Wykoff and Dr. Carmen Puliafito in a wide ranging discussion on what every c...
Focus on Dr. Jay S. Duker and EyePoint Pharmaceuticals
04 Mar 2021
Contributed by Lukas
Join us in a discussion with Jay S. Duker, MD Chief Strategic Scientific Officer of EyePoint Pharmaceuticals. Director of New England Eye Center, Prof...
Spotlight on Dr. Thomas Ciulla of Clearside Biomedical
26 Feb 2021
Contributed by Lukas
Thomas Ciulla, vitreoretinal surgeon and current Chief Medical Officer at Clearside Biomedical, discusses his journey through academics, private pract...
Focus on Dr. Karl Csaky and Vinci Pharmaceuticals
26 Feb 2021
Contributed by Lukas
Join us in a discussion with Dr. Karl Csaky CEO of Retina Foundation of the Southwest also Co-Founder of Vinci Pharmaceuticals with our moderator Dr. ...
Focus on Dr. Jason Ehrlich of Kodiak Sciences
26 Feb 2021
Contributed by Lukas
Join Charles C. Wykoff MD, PhD for a conversation with Jason Ehrlich, MD, PhD, Chief Medical Officer, Chief Development Officer at Kodiak Sciences. Ja...