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Short Wave

Bone Marrow Cells: Key To Vaccine Longevity?

14 Jan 2025

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The COVID-19 mRNA vaccine generates enough of an antibody response to protect against severe disease for six months. But other vaccines offer years-long — even lifelong — immunity, such as the measles or yellow fever vaccines. Is there a way for scientists to tell how long a person's immunity will last? A team at Stanford Medicine might have found a way to do just that — with the help of some of the cells found in our bone marrow. Questions about vaccines or the respiratory season? Email us at [email protected] — we'd love to hear from you!Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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0.189 - 17.201 Sponsor Message

Support for NPR and the following message come from the estate of Joan B. Kroc, whose bequest serves as an enduring investment in the future of public radio and seeks to help NPR produce programming that meets the highest standards of public service in journalism and cultural expression.

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18.482 - 31.802 Juana Summers

You're listening to Shortwave from NPR. Hey, short wavers, Emily Kwong here. And Jessica Young. With our bi-weekly science news roundup featuring the hosts of All Things Considered. And today we have Juana Summers.

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32.243 - 37.466 Emily Kwong

Hey, happy to be here. It's the first news roundup of the year. So tell me, what is going on in the world of science?

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37.827 - 54.769 Jessica Young

Well, there's a new study on how the longevity of a vaccine may be decided by our bone marrow. And then another one on the math and science behind hula hooping. And we have a roundup of what to look for over the next year in space news. Love it. All that on this episode of Shortwave, the science podcast from NPR.

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69.795 - 86.085 Sponsor Message

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88.567 - 95.711 Emily Kwong

Okay, I want to start with vaccines because it's feeling a little germy out there, y'all. There's so much flu and COVID going around. I am very glad I'm vaccinated.

96.004 - 116.788 Juana Summers

Yeah, vaccines are so powerful. They train your immune system to recognize and fight germs. And one of the ways they do so is by prompting your B cells to create antibodies. You can think of antibodies like security guards. So the COVID mRNA vaccine generates enough of an antibody response to protect against infection for three months and severe disease for six months.

117.409 - 121.389 Juana Summers

But other vaccines offer years-long, even lifelong immunity.

121.649 - 123.81 Emily Kwong

Lifetime security, like the measles vaccine.

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