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Short Wave

Can AI Crack The Biology Code?

03 Jun 2025

Description

As artificial intelligence seeps into some realms of society, it rushes into others. One area it's making a big difference is protein science — as in the "building blocks of life," proteins! Producer Berly McCoy talks to host Emily Kwong about the newest advance in protein science: AlphaFold3, an AI program from Google DeepMind. Plus, they talk about the wider field of AI protein science and why researchers hope it will solve a range of problems, from disease to the climate.Have other aspects of AI you want us to cover? Email us at [email protected] more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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Transcription

Full Episode

0.209 - 1.83 NPR Announcer

You're listening to Shortwave from NPR.

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27.435 - 31.737 Unknown

Hey, hey, short ravers. Emily Kwong here with producer Burleigh McCoy. What's up, Burleigh?

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31.877 - 44.001 Emily Kwong

Hey, Emily. Hello. What do you have for us today? Okay, so Emily, today I want to dig into how AI has shaken up the field of protein science, as in the fundamental building blocks of life, proteins.

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44.662 - 49.263 Unknown

I've heard of them. Yeah. I mean, this is like what you studied back in your scientist days.

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49.323 - 51.064 Emily Kwong

Yes. Yes. I love proteins.

51.504 - 55.085 Unknown

Oh, we love that you love them. How has AI moved the needle in this field, though?

55.405 - 71.451 Emily Kwong

Well, scientists have used it to dig into a problem that protein scientists have struggled with for more than 60 years. And that is, what do these building blocks, of which there are millions, look like? Like their shape? Like their shape. Yeah, exactly. And why is that so important?

71.771 - 85.32 Emily Kwong

Well, the ability of a protein to do its specific job, so like carry oxygen through your body or turn light into sugar, that relies wholly on its unique, complicated shape. So to understand how it works, you need to know its shape.

85.7 - 88.742 Unknown

But why can't scientists just run an experiment to determine the shape?

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