Talking Points

Episode 150: The TOMAHAWK Trial

06 Jul 2022

Contributed by Lukas

C. Michael Gibson and Steffen Desch discuss whether immediate angiography is warranted after out-of-hospital cardiac arrest.

Episode 149: The OPTIMUM Trial

22 Jun 2022

Contributed by Lukas

C. Michael Gibson and David Kandzari discuss PCI outcomes among patients at prohibitive risk for CABG.

Episode 148: The MASTER DAPT Trial

08 Jun 2022

Contributed by Lukas

C. Michael Gibson and Marco Valgimigli discuss dual antiplatelet therapy after coronary stenting in high-bleeding-risk patients.

Episode 147: The EROSION III Trial

01 Jun 2022

Contributed by Lukas

C. Michael Gibson, Haibo Jia, and Jingbo Hou discuss whether OCT guidance could cut stent use in STEMI without plaque rupture.

Episode 146: The LIFE Trial

18 May 2022

Contributed by Lukas

C. Michael Gibson and Douglas Mann discuss sacubitril/valsartan in patients with advanced HFrEF.

Episode 145: PRAGUE 17: LAA Closure vs DOACs

04 May 2022

Contributed by Lukas

C. Michael Gibson and Pavel Osmancik review 3-year results with LAA closure versus a DOAC for patients with atrial fibrillation.

Episode 144: MASTER DAPT: High-Risk Patients

20 Apr 2022

Contributed by Lukas

C. Michael Gibson and Pieter C. Smits review outcomes in high-bleeding-risk patients also at high risk for thrombotic events who were randomized to ab...

Episode 143: The ADAPTABLE Study: Patient-Centered Aspirin

06 Apr 2022

Contributed by Lukas

C. Michael Gibson discusses aspirin dosing and long-term effectivness with Schuyler Jones and Greg Merritt.

Episode 142: ISCHEMIA: Complete Revascularization and QoL

23 Mar 2022

Contributed by Lukas

C. Michael Gibson and Kreton Mavromatis discuss how completeness of revascularization impacts quality of life in stable ischemic heart disease patient...

Episode 141: The STRENGTH Study of Omega-3s

16 Mar 2022

Contributed by Lukas

C. Michael Gibson and Steven Nissen discuss the link between omega-3 fatty acid levels and MACE in patients with high cardiovascular risk.

Episode 140: The SWISS-APERO Trial

02 Mar 2022

Contributed by Lukas

C. Michael Gibson and Robert Galea discuss Amulet versus Watchman for LAA closure.

Episode 139: The 2021 ESC HF Guidelines

09 Feb 2022

Contributed by Lukas

C. Michael Gibson and Carolyn Lam discuss key updates to the European heart failure guidelines and how best to initiate medications to optimize outcom...

Episode 138: The ATLANTIS Trial: DOACs in TAVI?

02 Feb 2022

Contributed by Lukas

C. Michael Gibson, Jean-Philippe Collet, and Gilles Montalescot and discuss apixiban after TAVI in the Atlantis trial.

Episode 137: Early Intrepid TMVR Results

12 Jan 2022

Contributed by Lukas

C. Michael Gibson and Firas Zahr discuss 30-day outcomes following transfemoral transseptal TMVR.

Episode 136: Two DCBs vs POBA in Coronary In-Stent Restenosis

05 Jan 2022

Contributed by Lukas

C. Michael Gibson and Bruno Scheller discuss 1-year outcomes of two parallel RCTs.

Episode 135: The ULTIMATE Trial

22 Dec 2021

Contributed by Lukas

Junjie Zhang and C. Michael Gibson discuss 3-year outcomes after IVUS- versus angiography-guided DES implantation.

Episode 134: The PROSPECT ABSORB Trial

08 Dec 2021

Contributed by Lukas

Gregg Stone and C. Michael Gibson discuss a randomized trial examining interventional treatment of vulnerable plaques.

Episode 133: The COBRA-REDUCE Trial

02 Dec 2021

Contributed by Lukas

Robert Byrne and C. Michael Gibson discuss a randomized trial of a thromboresistant Polyzene F-coated stent with 14-day DAPT in high-bleeding-risk pat...

Episode 132: The RIVER Trial

10 Nov 2021

Contributed by Lukas

Otavio Berwanger and C. Michael Gibson discuss rivaroxaban versus warfarin in patients with bioprosthetic mitral valves and atrial fibrillation or flu...

Episode 131: The SCOPE II Trial

03 Nov 2021

Contributed by Lukas

Corrado Tamburino and C. Michael Gibson discuss a randomized trial of two self-expanding TAVR bioprostheses.

Episode 130: The DISRUPT CAD III Trial

20 Oct 2021

Contributed by Lukas

Dean Kereiakes and C. Michael Gibson discuss intravascular lithotripsy for the treatment of severe coronary calcification.

Episode 129: The TICO-STEMI Trial

06 Oct 2021

Contributed by Lukas

Byeong-Keuk Kim and C. Michael Gibson discuss a randomized trial of ticagrelor monotherapy versus ticagrelor with aspirin in STEMI.

Episode 128: The COMPARE CRUSH Trial

22 Sep 2021

Contributed by Lukas

Georgios Vlachojannis and C. Michael Gibson discuss a randomized trial of prehospital crushed versus uncrushed prasugrel in STEMI.

Episode 127: The SOLOIST-WHF and SCORED Trials

08 Sep 2021

Contributed by Lukas

Deepak Bhatt and C. Michael Gibson discuss data on sotagliflozin in diabetes.

Episode 126: The REFLECT II Trial

25 Aug 2021

Contributed by Lukas

Jeffrey Moses and C. Michael Gibson discuss a randomized trial of cerebral embolic protection during TAVR.

Episode 125: The TIPS-3 Trial

18 Aug 2021

Contributed by Lukas

Salim Yusuf and C. Michael Gibson discuss aspirin alone and in combination with a polypill for CVD primary prevention.

Episode 124: The MITHRAS Trial

04 Aug 2021

Contributed by Lukas

Philipp Lurz and C. Michael Gibson discuss a randomized trial of ASD closure after TMVr.

Episode 123: The XIENCE 90/28 Trial

21 Jul 2021

Contributed by Lukas

Roxana Mehran and C. Michael Gibson discuss 3-month and 1-month DAPT after everolimus-eluting stents in high-bleeding-risk patients.

Episode 122: The MSTOPS Trial

07 Jul 2021

Contributed by Lukas

Steven Steinhubl and C. Michael Gibson discuss 3-year outcomes in a nationwide, randomized, pragmatic clinical trial of A-fib screening.

Episode 121: The TARGET FFR Trial

23 Jun 2021

Contributed by Lukas

Damien Collison and C. Michael Gibson discuss a randomized trial of physiology-guided PCI optimization.

Episode 120: The STRENGTH Trial

16 Jun 2021

Contributed by Lukas

A. Michael Lincoff and C. Michael Gibson discuss CV outcomes with omega-3 carboxylic acids in patients with high vascular risk and atherogenic dyslipi...

Episode 119: The STRENGTH Trial

02 Jun 2021

Contributed by Lukas

A. Michael Lincoff and C. Michael Gibson discuss CV outcomes with omega-3 carboxylic acids in patients with high vascular risk and atherogenic dyslipi...

Episode 118: The OPTIMIZE Trial

19 May 2021

Contributed by Lukas

Dean Kereiakes and C. MIchael Gibson discuss a randomized trial of a novel, ultra-low-profile fixed-wire DES.

Episode 117: The AHA COVID-19 CVD Registry

06 May 2021

Contributed by Lukas

Robert Harrington and C. Michael Gibson discuss the registry's design, implementation, and initial results.

Episode 116: The TANGO Trial

21 Apr 2021

Contributed by Lukas

Ehrin Armstrong and C. Michael Gibson discuss a randomized, dose-escalation trial of temsirolimus adventitial delivery below the knee.

Episode 115: The GALACTIC-HF Trial

07 Apr 2021

Contributed by Lukas

John Teerlink and C. Michael Gibson discuss omecamtiv mecarbil in chronic HFrEF.

Episode 114: The NACMI COVID-19 Registry

24 Mar 2021

Contributed by Lukas

Timothy Henry and C. Michael Gibson discuss outcomes from the North American registry.

Episode 113: The EXPLORER-HCM Trial

17 Mar 2021

Contributed by Lukas

Iacopo Olivotto and C. Michael Gibson discuss mavacamten in adults with symptomatic obstructive hypertrophic cardiomyopathy.

Episode 112: FLASH Registry: Acute Hemodynamic Improvement

03 Mar 2021

Contributed by Lukas

C. Michael Gibson and Catalin Toma discuss acute hemodynamic improvement with percutaneous mechanical thrombectomy in a real-world pulmonary embolism ...

Episode 111: The PARALLAX Trial

17 Feb 2021

Contributed by Lukas

Burkert Pieske and C. Michael Gibson discuss sacubitril/valsartan versus individualized RAAS blockade in HFpEF.

Episode 110: The HOME-PE Trial

03 Feb 2021

Contributed by Lukas

Pierre-Marie Roy and C. Michael Gibson discuss hospitalization or outpatient management of PE.

Episode 109: The EAST-AFNET 4 Trial

20 Jan 2021

Contributed by Lukas

Paulus Kirchhof and C. Michael Gibson discuss early rhythm control therapy in patients with atrial fibrillation.

Episode 108: The BPLTTC Trial

06 Jan 2021

Contributed by Lukas

Kazem Rahimi and C. Michael Gibson discuss BP-lowering for prevention of cardiovascular events.

Episode 107: LoDoCo2 Low-Dose Colchicine in Coronary Disease

16 Dec 2020

Contributed by Lukas

Dr. Jan Cornel and Dr. C. Michael Gibson Discuss: LoDoCo2 Low-Dose Colchicine in Coronary Disease.

Episode 106: TCT Connect 2020

02 Dec 2020

Contributed by Lukas

C. Michael Gibson, Ajay Kirtane, Mamas Mamas, and Roxana Mehran talk TCT 2020.

Episode 105: POPULAR TAVI

04 Nov 2020

Contributed by Lukas

C. Michael Gibson and Jorn Brouwer discuss aspirin with or without clopidogrel after transcatheter aortic valve replacement.

Episode 104: EMPEROR Reduced

21 Oct 2020

Contributed by Lukas

C. Michael GIbson and Milton Packer Discuss empagliflozin in heart failure with reduced ejection fraction.

Episode 103: New ESC NSTEMI Guidelines

07 Oct 2020

Contributed by Lukas

C. Michael Gibson and Roxana Mehran discuss new ESC NSTEMI guidelines and more

Episode 102: Innovation in Mitral Valve Repair

02 Sep 2020

Contributed by Lukas

C. Michael Gibson and Steven Goldberg discuss REDUCE-FMR and sham-controlled trials in MV repair.

Episode 101: PARTNER 2A: 5-Year Outcomes

19 Aug 2020

Contributed by Lukas

C. Michael Gibson and Vinod Thourani discuss 5-year outcomes in this randomized trial of TAVR vs SAVR in intermediate-risk patients.

Episode 100: COAPT Cost-effectiveness Analysis Plus Health-Status Outcomes in PARTNER 3

05 Aug 2020

Contributed by Lukas

Suzanne Baron and C. Michael Gibson discuss important new details from these two structural heart disease trials.

Episode 99: EVOLVE Short DAPT: 3-Month DAPT in Patients

22 Jul 2020

Contributed by Lukas

C. Michael Gibson and Ajay Kirtane review the results of this single-arm stent study.

Episode 98: #WomenAs1: The Battle for Gender Equality

15 Jul 2020

Contributed by Lukas

Roxana Mehran brings C. Michael Gibson up to speed on a campaign to promote talent in medicine by offering professional opportunities to female physic...

Episode 97: TWILIGHT: Impact of Ticagrelor Alone vs. Ticagrelor Plus Aspirin

02 Jul 2020

Contributed by Lukas

Usman Baber, who led this thrombogenicity substudy, walks C. Michael Gibson through the key findings.

Episode 96: IVUS-XPL: Intravascular Ultrasound-Guided vs. Angiography-Guided PCI

17 Jun 2020

Contributed by Lukas

C. Michael Gibson and Myeong-Ki Hong discuss 5-year outcomes in this randomized trial.

Episode 95: FORZA: Randomized Trial of Fractional Flow Reserve

20 May 2020

Contributed by Lukas

What are the respective values of FFR and OCT in guiding revascularization? C. Michael Gibson gets a primer from Francesco Burzotta.

Episode 94: Wearables - The Future Is Now

22 Apr 2020

Contributed by Lukas

C. Michael Gibson connects with Sameer Mehta and Francisco Fernandez to hear how new tech is poised to disrupt medical care.

Episode 93: Onyx ONE

17 Apr 2020

Contributed by Lukas

C. Michael Gibson learns about the Onyx ONE trial from Stephan Windecker.

Episode 92: TWILIGHT: Ticagrelor Monotherapy vs Ticagrelor Plus Aspirin

01 Apr 2020

Contributed by Lukas

C. Michael Gibson reviews the randomized TWILIGHT trial results with Roxana Mehran.

Episode 91: Propensity Score-Matched Analysis

18 Mar 2020

Contributed by Lukas

Maurizio Taramasso walks C. Michael Gibson through randomized data focused on tricuspid valve disease.

Episode 90: MODEL U-SES: 3-Month DAPT in Patients at High Bleeding Risk

04 Mar 2020

Contributed by Lukas

C. Michael Gibson hears from Ken Kozuma about the single-arm MODEL U-SES study.

Episode 89: STS Registry: Mitral Valve Surgery Institutional Volume-Outcome Relationship in the US

24 Feb 2020

Contributed by Lukas

Vinay Badhwar discusses new data from the STS Registry addressing volume/outcome relationships for mitral valve surgery.

Episode 86: REMEDIAL III: Urine Flow Rate-Guided vs LVEDP-Guided Hydration

16 Jan 2020

Contributed by Lukas

C. Michael Gibsons sits down with Carlo Briguori to discuss the REMEDIAL III trial results.

Episode 85: REDUCE-FMR: Percutaneous Mitral Annuloplasty in Functional Mitral Regurgitation

07 Jan 2020

Contributed by Lukas

Samir Kapadia, Horst Sievert, and C. Michael Gibson discuss this randomized sham-controlled trial of the Carillon device.

Episode 84: A Novel Subcutaneous Platelet GPIIb/IIIa Inhibitor in STEMI

18 Dec 2019

Contributed by Lukas

C. Michael Gibson and Dean Kereiakes discuss the first human use of RUC-4, designed for STEMI point-of-care treatment.

Episode 83: The Medically Ill Patients in AUGUSTUS

04 Dec 2019

Contributed by Lukas

C. Michael Gibson discusses the AUGUSTUS trial with Renato Lopes.

Episode 82: EXCEL: 5-Year Outcomes

20 Nov 2019

Contributed by Lukas

C. Michael Gibson speaks with Gregg Stone about EXCEL: 5-Year Outcomes From a Randomized Trial of PCI vs. CABG in Patients With Left Main Coronary Art...

Episode 81: COAPT 3-Year Outcomes

06 Nov 2019

Contributed by Lukas

C. Michael Gibson speaks with Michael Mack about the COAPT Trial 3-year outcomes and results.

Episode 80: PARTNER 3 Low-Risk Computed Tomography Substudy

25 Oct 2019

Contributed by Lukas

C. Michael Gibson speaks with Raj Makkar about PARTNER 3 Low-Risk Computed Tomography Substudy: Subclinical Leaflet Thrombosis in Transcatheter and Su...

Episode 79: LEVANT: 5-Year Outcomes From Three Randomized Trials

16 Oct 2019

Contributed by Lukas

C. Michael Gibson speaks with Kenneth Ouriel about LEVANT: 5-Year Outcomes From Three Randomized Trials of Percutaneous Angioplasty With vs. Without a...

Episode 78: REDUCE-FMR: A Sham-Controlled Randomized Trial

18 Sep 2019

Contributed by Lukas

C. Michael Gibson sits down with Horst Sievert to learn more about the REDUCE-FMR trial.

Episode 77: PREPARE-CALC: High-speed Rotational Atherectomy Prior to Drug-Eluting Stent Implantation

04 Sep 2019

Contributed by Lukas

C. Michael Gibson gets the details on PREPARE-CALC from Gert Richardt.

Episode 76: Annapoorna Kini: Clinician, Researcher, Educator, and App Developer

22 Aug 2019

Contributed by Lukas

C. Michael Gibson learns more about Annapoorna Kini's work and why the field needs female role models.

Episode 75: CorMicA: A Randomized Trial of Invasive Coronary Function Testing

07 Aug 2019

Contributed by Lukas

C. Michael Gibson and Tom Ford discuss the potential for finding and treating patients with ANOCA.

Episode 74: Quality of Life in the COAPT Study

24 Jul 2019

Contributed by Lukas

C. Michael Gibson and David Cohen discuss adding years to life and adding life to years with the MitraClip.

Episode 73: COMPARE ABSORB

17 Jul 2019

Contributed by Lukas

C. Michael Gibson and Pieter Smits walk us through the COMPARE ABSORB trial.

Episode 72: NEOPRO: Nonrandomized Comparison of Two Transcatheter Heart Valves

03 Jul 2019

Contributed by Lukas

C. Michael Gibson and Azeem Latib take a closer look at some next-gen TAVR devices.

Episode 71: ULTIMATE: A Randomized Trial of Intravascular Ultrasound Guidance

18 Jun 2019

Contributed by Lukas

C. Michael Gibson and Junjie Zhang discuss ULTIMATE: A Randomized Trial of Intravascular Ultrasound Guidance of Coronary Drug-Eluting Stent Implantati...

Episode 70: FAST-FFR: Accuracy of Fractional Flow Reserve Derived From Coronary Angiography

05 Jun 2019

Contributed by Lukas

C. Michael Gibson and William Fearon talk FFR-CT.

Episode 69: SOLVE-TAVI: A 2x2 Randomized Trial of Transcather Aortic Valve Implantation

24 May 2019

Contributed by Lukas

C. Michael Gibson and Holger Thiele take a deep dive into a head-to-head trial of TAVR devices that also considered general versus local anesthesia.

Episode 68: TALENT: A Randomized Trial

15 May 2019

Contributed by Lukas

C. Michael Gibson talks with Patrick Serruys about, TALENT: A Randomized Trial Evaluating an Ultra-Thin Strut Bioresorbable Polymer-Based Coronary Dru...

Episode 67: RESET: Randomized Trial of Sirolimus-Eluting vs Everolimus-Eluting Stents

01 May 2019

Contributed by Lukas

C. Michael Gibson and Hiroki Shiomi look at long-term outcomes from RESET.

Episode 66: PORTICO I: One-Year Outcomes

17 Apr 2019

Contributed by Lukas

C. Michael Gibson and Lars Sondergaard discuss 1-year outcomes in the PORTICO I trial.

Episode 65: SECURE-PCI: Impact of Timing of Atorvastatin Loading Dose

03 Apr 2019

Contributed by Lukas

Does timing of an atorvastatin loading dose make a difference in PCI for ACS? C. Michael Gibson and Renato Lopes discuss.

Episode 64: Building a New Backbone Upon Which to Randomize Patients: PERT Registry

20 Mar 2019

Contributed by Lukas

C. Michael Gibson, Kenneth Rosenfield, and Robert Lookstein discuss the way forward for PERT.

Episode 63: TRIVALVE: Evaluation of Edge-to-Edge Valve Repair

06 Mar 2019

Contributed by Lukas

C. Michael Gibson and Jörg Hausleiter discuss the TRIVALVE trial.

Episode 62: BIONYX: A Randomized Trial

20 Feb 2019

Contributed by Lukas

C. Michael Gibson and Clemens von Birgelen discuss the BIONYX randomized trial.

Episode 61: ReCre8: A Randomized Trial Evaluating a Polymer-Free Coronary Drug-Eluting Stent

06 Feb 2019

Contributed by Lukas

C. Michael Gibson and Pieter Stella discuss ReCre8, which evaluated a polymer-free DES in an all-comers population.

Episode 60: What Do You Get When You Combine Twitter and a Textbook? Tweetbook

23 Jan 2019

Contributed by Lukas

What do you get when you combine Twitter and a textbook? C. Michael Gibson talks with Michael Savage and David Fischman.

Episode 59: IMPERIAL: A Randomized Trial of Drug-Eluting Stents

09 Jan 2019

Contributed by Lukas

C. Michael Gibson talks to William Gray about IMPERIAL: A Randomized Trial of Drug-Eluting Stents for Treatment of Femoropopliteal Artery Lesions.

Episode 58: 2018 North American Consensus Statement for Atrial Fibrilation Patients Undergoing PCI

02 Jan 2019

Contributed by Lukas

C. Michael Gibson speaks with Dominick Angiolillo about the 2018 North American Consensus Statement for Atrial Fibrilation Patients Undergoing PCI.

Episode 47: INTREPID

07 Jun 2018

Contributed by Lukas

Early results with a new device being developed for transcatheter MV replacement are promising, Paul Sorajja tells C. Michael Gibson.

Episode 46: DAPT-STEMI

18 May 2018

Contributed by Lukas

C. Michael Gibson gets the details from DAPT-STEMI from Elvin Kedhi.

Episode 34: TRACER

08 Jan 2018

Contributed by Lukas

TRACER: 6-Month Outcomes of Transcatheter MV Neochordal Repair in Patients With Severe Primary Mitral Regurgitation

Episode 35: TENDYNE Trial

08 Jan 2018

Contributed by Lukas

Dr. C. Michael Gibson talks to Dr. David W. M. Muller about TENDYNE: 1-Year Outcomes of Transcatheter MV Replacement in Patients With Severe Mitral Re...

Episode 33: DKCRUSH-V Trial

06 Dec 2017

Contributed by Lukas

Dr. C. Michael Gisbon talks to Dr. Shao-Liang Chen about the DKCRUSH-V: A Randomized Trial of Double Kissing Crush vs Provisional Stenting for Treatme...

Episode 31: PLATINUM DIVERSITY - Outcomes With Coronary Stenting in Women and Minorities

06 Dec 2017

Contributed by Lukas

C. Michael Gibson reviews new registry results with Wayne Batchelor.

Episode 32: COLOR

30 Nov 2017

Contributed by Lukas

Listen to C. Michael Gibson in conversation with Giora Weisz. Color: A Multicenter Registry Looking at Lipid-Rich Plaque & 2-Year Outcomes After Stent...

Episode 30: PARTNER 2 Quality of Life

20 Sep 2017

Contributed by Lukas

C. Michael Gibson discusses health-status benefits in intermediate-risk patients treated with surgical or transcatheter aortic valve replacement.

Episode 29: ILLUMENATE US

06 Sep 2017

Contributed by Lukas

C. Michael Gibson sits down with Sean Lyden to discuss the results.