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The Downstream Column Podcast

News Science

Activity Overview

Episode publication activity over the past year

Episodes

Advancements in Buffer Management and Single Use Inline Buffer Formulation

23 Feb 2024

Contributed by Lukas

In this podcast, we spoke with Nainesh Shah, Senior Application Engineer at Asahi Kasei Bioprocess about buffer management including the benefits of i...

New online Gene Therapy Academy offers great resources to support scaling up from lab to production scale

05 Oct 2022

Contributed by Lukas

In this podcast, we spoke with Emanuel Krobath, Biopurification Specialist and Chiara Pacini, Bioprocess Specialist both with Pall Corporation about ...

A Guide for Navigating the Single Use Technology Supply Chain

20 Sep 2022

Contributed by Lukas

In this podcast we spoke with Derrick Alig, North American Western Regional Sales Manager for PSG Dover Biotech, Chris Couper, President and Founder o...

Manufacturing high concentration mAbs challenges and solutions

25 Aug 2022

Contributed by Lukas

In this podcast, we spoke to Tom Watson, Group Leader, Product Management – Biotech Division, Gregor Kalinowski, Manager SLS Purification Consultant...

Biomanufacturing Quality Management Systems – A holistic approach

11 Aug 2022

Contributed by Lukas

In this podcast, we interviewed Katie Keller, Director of Quality and Safety at Asahi Kasei Bioprocess America, about the importance of quality manage...

Flexible single-use mixers are key to achieving a next level mixing experience and reducing delivery lead times

27 Jul 2022

Contributed by Lukas

In this podcast we spoke with Klaus Kienle, Global Product Manager for the Mixing portfolio at Pall Corporation about the latest mixing technologies i...

Optimizing Process Development Early – A critical factor in successful viral vector scale up and large scale manufacture

12 Jul 2022

Contributed by Lukas

In this podcast, I spoke with John Ketz and Denis Kole about viral vector production, including current manufacturing challenges, navigating the road ...

Single-use Mixers – Ensuring the Customization, Scalability and Supply Required for Success

25 May 2022

Contributed by Lukas

In this podcast, we talked with Dennis Hodgson and Phil Sanders from Agilitech about the benefits of single-use mixers, dealing with supply chain conc...

Increasing Liquid Chromatography Efficiency with Fully-controlled Binary Blending

19 May 2022

Contributed by Lukas

Cory Hinz talks about the different methods that are available for liquid chromatography mobile phase solutions and the benefits of inline blending. C...

Addressing the increasing demand for single-use technologies and supply chain shortages with future proof systems

28 Oct 2021

Contributed by Lukas

Phil Sanders talks about the increase in demand for single-use equipment and consumables and how this has led to supply chain shortages.

Evolving Beyond the Status Quo with Next Generation Buffer Prep Solutions

17 Aug 2021

Contributed by Lukas

In this podcast, we spoke with Chris Rombach, Vice President of Sales and Marketing at Asahi Kasei Bioprocess America about buffer prep and delivery s...

Integrated Freezing Solutions to Minimize Risk and Preserve Product Quality

27 Apr 2021

Contributed by Lukas

Claire Jarmey-Swan, Global Product Manager, Pall Corporation talks about the evolution freeze thaw technologies and how these new methods can streamli...

Start With The End In Mind. How to facilitate transfer from non-GMP to GMP Manufacturing

28 Jun 2018

Contributed by Lukas

Avril Vermunt, bioprocess hardware specialist at GE healthcare talks about transferring a process from non-GMP to GMP manufacturing, particularly how ...

Modeling Downstream Disruptive Technologies to Improve Downstream Bioprocessing.

07 Jun 2018

Contributed by Lukas

Dr. Yuyi Shen, Principal Scientist, Grifols, talks about the benefits of modeling downstream disruptive technologies to improve downstream bioprocessi...

Cell Harvesting – Selecting a technology compatible with cell density and feed turbidity

10 Apr 2018

Contributed by Lukas

Silke Bergheim-Pietza, Global Product Manager Depth Filtration, Pall. discusses challenges faced in the cell harvesting step, in particular, selecting...

Continuous Biomanufacturing Implementation Now and in The Future

06 Mar 2018

Contributed by Lukas

Dr. Peter Levison, Senior Marketing Director – Downstream Processing, Pall Biotech talks about the evolution and benefits of continuous biomanufactu...

Addressing Challenges in Downstream Biomanufacturing with a Platform Purification Approach

31 Jan 2018

Contributed by Lukas

Jonathan Royce, Business Leader, Chromatography Resins, GE Healthcare Life Sciences, talks about the biggest challenges in Downstream biomanufacturing...

Protein A Chromatography – A look at where we have been and where we are going

12 Dec 2017

Contributed by Lukas

Jonathan Royce, Business Leader, Chromatography Resins, GE Healthcare Life Sciences, talks about the evolution of Protein A including the latest devel...

Resolving Large Scale Buffer Management Challenges

29 Nov 2017

Contributed by Lukas

Joakim Lundvist, Modality Manager, BioProcess™ Hardware, GE Healthcare talks about large-scale buffer management challenges. Buffer preparation is k...

Job Outlook for the Biomanufacturing Industry a Recruiter’s Perspective

05 Apr 2017

Contributed by Lukas

Hillary Kaplan, Director, Bioprocess CMC Development & Operations, Klein Hersh talks about the job outlook for the biomanufacturing industry from a re...

Cell Culture Media Optimization – It’s about more than just high protein titer

19 Jul 2016

Contributed by Lukas

Dr. Adam Elhofy, Ph.D., CSO, Essential Pharmaceuticals, talks about cell culture media optimization. We discussed the evolution of cell culture media ...

Automated Stem Cell Based High Throughput Drug Screening for ALS and Parkinson’s

14 Jun 2016

Contributed by Lukas

Dr. Jan Bruder talks about his work at the Max Planck Institute for Molecular Biology in Münster Germany and his group’s use of automated high thro...