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The Dr Pompa Podcast

Dr. Pompa Solo: This Popular Fast Destroys Your Muscle

13 Dec 2025

Transcription

Transcript generated automatically by AI and may contain errors.

Chapter 1: What is partial fasting and how does it work?

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have you heard of a partial fast all right can it extend your life can it prevent diseases like cancer autoimmune and even wait fixed diabetes okay one thing if i taught on over my years of teaching doctors that has the power to do everything that i just said outside of detox because that's been my message it's fasting

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But I would argue that most people, when they think about an extended fast, that means in my mind, three, five days or more. And I prefer five day fast as a minimum, to be honest with you. I'll talk about the reason for that. They would just think, oh, my gosh, going without food is very difficult. All right, well, partial fasting is actually where I like to start most people into a fast.

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So that means that you can actually eat a little bit of food every day and achieve the same results, oftentimes for some people, better results. And I'll tell you why. Okay, so what is a partial fast and how do you do it? Okay, I think first of all, partial fasting is a safer way to fast for many people taking medications and even her just very metabolically challenged.

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I think partial fasting is a way to actually increase your results and arguably it's easier, at least emotionally, because if you think about eating a little food every day, versus taking away all food, which one sounds more challenging? Well, I would argue that most people would say that a little food sounds easier than taking away all food. But I'm going to be honest with you.

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I prefer actually pure water fasting. Now, I've done an episode on dry fasting where you don't do food or water, another subject. But the fact is that for me, eating a little bit of food, I just want to keep eating. But that's not the case for most people. Most people find partial fasting easier. But why did I say that maybe you get better results? Well, here's why.

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Because when you take all food away from many people, their body is so broken at the cellular level. that they have an inability to utilize fat as energy and therefore they have an inability also to go into what we call autophagy. Their body resists going into autophagy and they break down muscle into glucose. And that is not a good thing.

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It's called gluconeogenesis because then the fast is very, very challenging and oftentimes they lose the wrong weight. Okay. So water fasting may not be for everybody, but I believe partial fasting is where most people actually get the most benefit and should start.

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So the fact is that people would say, yeah, but if you're eating a little bit of food, wouldn't you actually take away the benefits of fasting, that autophagy that you talk about? So let me just start from the top in case you haven't seen some of my other fasting episodes. So in a fasted state, the body needs to survive.

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So it breaks down only bad cells in the body that are typically called senescent cells. These are cells that live too long. These are cells that drive inflammation, that also drive autoimmune, even cancer. So we want to get rid of these cells. The body's so smart that in a fasted state, it eats those bad cells. And here's the best part. It stimulates a stem cell to replace it.

Chapter 2: Why is partial fasting considered easier for most people?

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I would argue that because you're looking at studying the average person who really is not really fat adapted. And when they fast, they don't really dig into that autophagy until maybe day four or five or six. Okay. So the fact is, is I would agree. The average person will get more autophagy in a partial fast than they actually would in a pure water fast. Now, if you're a seasoned faster,

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I believe Walter's wrong on that, and I love Walter, but I do disagree with him. I believe that an absolute seasoned faster will get more autophagy, meaning getting rid of more of those bad cells doing a water fast than they would a partial fast. That said, the majority of people I think will benefit more starting with a partial fast.

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So let me tell you what it is, how to do it, because I think that's the most important part. But let me tell you a story first, because in the 90s, I was into fasting. I studied fasting. Herbert Shelton wrote all the books on fasting, and I read all of them.

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Matter of fact, I was going to all of these Natural Hygiene Society seminars where it was a bunch of vegan vegetarians, and then there was me who wasn't. And because I was there because these were big fasters. They had some of the best fasting scientists in the world talking at their seminars.

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So I would show up at these things and I would even go to fasting clinics and I wanted to know everything about fasting. And well, I found this French gentleman, Albert Mazur. And he was a big extended water faster. People would go to his clinics and they would spend a lot of time there extended fasting. But what he found was very interesting.

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He found that oftentimes when people would hit the wall on like, you know, 30, 40, 50, 60 day fast, I think most of his were at least a month. I mean, he fasted people a long time. What would happen is when they would start to break the fast, he would notice that they would break through certain health conditions and even like turn bright eyed and they would just feel absolutely amazing.

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And he would also notice that certain things like on their skin would start to clear up. So he knew, even though he didn't know a lot about autophagy then, this is new science, this science around autophagy, the body feeding from bad cells, but he knew that something amazing happened and kept going in the healing process. That's what he identified after they would break the fast. Now,

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You have to understand, you don't just break a fast and start eating normal again. You break a fast with little amounts of food, aka a partial fast. So when you come out of a pure water fast, you break it with a partial fast. But he would notice this phenomena of like these incredible healings that would happen while they were in the partial fast. So guess what he did?

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He would actually extend this partial fast even further And he would see these results escalating as this partial fast would go on. He came up with an idea of saying, wait a minute, these really sick people that oftentimes we don't get the good results with a water fast. Let me just start them in a partial fast and just partial fast them.

Chapter 3: How does partial fasting compare to traditional water fasting?

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Proloan gives you a box of food day one box of food for day two around all those parameters that I just told you about. And he believes even a perfect balance of the food. It's a good thing.

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However, I'm oftentimes in my doctors that I train dealing with people who have a lot of challenges, a lot of mast cell activation sensitivities, and they have to build their own around the rules that I just set out for you. So it's pretty easy, right? You get up in the day and you can eat as many times as you want. When I partial fast, I typically still like to eat two meals a day.

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But some people do just like to eat throughout the day. And for this, really, it's OK, because keeping your calories under the thousand or eight hundred or six hundred, depending on body size and keeping the protein under the 20 grams or 15 grams. will keep you in autophagy. And as I pointed out, Walter actually showed that people still get max autophagy even in a partial fast.

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So here's the way I tell people to fast always. Get yourself a glucose ketone meter. If you go to KetoMojo.com, KetoMojo.com, you can buy one that does glucose and ketones. And I always say, test your first morning glucose and ketones. Throughout a fast, you should see glucose dropping and ketones rising. When you hit a one-to-one ratio, we know that someone enters into what we call maxotophagy.

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Now, this is something that I put together, Thomas Seyfried used this one-to-one ratio. They noticed that when tumors in a fasted state would stop shrinking, then they left that maxotophagy. When they would continue to shrink at a high rate, they were maxotophagy. And he noticed this one-to-one ratio.

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They saw the fastest shrinkage in tumors, maxotophagy, meaning you're getting rid of a lot of bad cells. But let me point out something. This is important. So if you're taking notes, if your glucose is, say, 90%,

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you have to divide 90 or if it's 80 90 doesn't matter but you divide the glucose by 18 and now you get a number more like 3.8 right so you i didn't do the math in my head correctly perhaps but um but you get a number that now matches the ketones and millimolars so You now compare that to the ketones. So your ketones in a fasted state are typically going to be 2.8, 4.8, even up to 8.8.

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I don't know why I keep saying the point. I'm just using examples. So it could be eight. It could be, you know, but when you enter something called ketosis, you're above 0.5 and above. But when a fasted state, typically you're getting very high ketones, three point something, four point something, five point something. You get the point and then you compare it to the glucose.

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When it's one to one, so let's say your ketones are 3.3, you divide your glucose by 18 and it's 3.3, one to one ratio, max autophagy. Now, let's say your ketones are 4.5 and your glucose is, it comes out to be 3.1. Now you're even more max autophagy. So the higher the ketones, the lower the glucose, the more autophagy. Make sense?

Chapter 4: What are the benefits of autophagy in fasting?

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So how many people want to plan the next maybe plan three months? We're at five days. Next month, pick another five days. Next month, another five days. Now, let me challenge you. I teach something called feast famine, where I believe the feasting is as important as the famine.

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If you have five days where you're eating very less, a lot less in a partial fast, a month, I would say pick five days somewhere else in the month. Ladies, best time is the week before your cycle. Pick five days in feast. What is a feast? You'll perhaps eat more meals if you're an intermittent faster, maybe three, four meals for five days in a row or even a week. Break it up is my point.

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Maybe it's high protein where you're trying to get one gram of protein per pound of body weight. So lean body weight. So if your lean body weight is 130 pounds, you try to get 130 grams of protein in that day. That could be a feast, right? Even more for some people, but high protein is a feast. More food and more meals is a feast.

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And also it could be more carbohydrates if you're someone who, healthy carbs, if you're someone who runs low carbs all the time.

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feasting is as important as the fasting it reminds the body it's not starving remember what happened in the biosphere 2 project low calorie too long not good but also putting the body in that anabolic state a lot of healing happens and i would say most women we tend to need to feed them up like that feasting is really important it fires up the metabolism and then you get more benefit

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when you actually fast. And now you're in the state of autophagy. Look, the feast famine, there's two pathways that are at play here. I already taught you one. The pathway in fasted state, whether partial or pure water, is autophagy. The body's getting rid of bad cells. That's a catabolic state, meaning getting rid of. But in a feast, The body is stimulating a pathway called mTOR.

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Now, anti-agers would say mTOR ages you prematurely. It can drive cancer. Well, if you stay in that feasted state long, disaster. It does do that. Matter of fact, same criticism here. When the people in the Biosphere 2 project stayed in that autophagy state, reducing calories, they became catabolic. They lowered their immunity. It was a fail. So either...

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autophagy or mtor too long is bad so you don't want to feast too long which this is what a lot of americans do their every day is a feast not good okay but times of feasting five days a month perhaps in times of famine

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is magic even weekly we do this so if we have like one or two days a week where we one meal or no meals okay there's the famine state but we add a couple days in where we feast wake up and eat three four meals that day higher protein just as i described feast famine creates a hormetic stress on the body it actually improves your microbiome it actually improves your microbiome and it actually adds diversity into the microbiome

Chapter 5: How can partial fasting help with metabolic challenges?

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When you do these types of fasts, what your body does is it gets rid of these hyperimmune cells. Then it stimulates a stem cell and creates a naive immune cell, which doesn't overreact. So it's a way to reverse the hyperimmunity, often called autoimmunity. But I challenge many people to do it. Partial fast. Try it. Watch what happens to your health. Share this episode.

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People need to know this information. And stay tuned for the next incredible podcast, Dr. Pompa Podcast.

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