The Genetics Podcast

EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern

02 May 2024

Contributed by Lukas

Join us as we welcome Dr. Emma Magavern to The Genetics Podcast! In addition to being a medical doctor with an English Literature degree, Dr. Magovern...

EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church

25 Apr 2024

Contributed by Lukas

In this episode, we are excited to welcome George Church, Professor at Harvard Medical School and MIT, and Co-founder of Eugit Therapeutics, Colossal ...

EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens

18 Apr 2024

Contributed by Lukas

In this episode, we welcome Jake Rubens, a seasoned genomic science entrepreneur and co-founder of Quotient Therapeutics. Tune in to hear Jake discuss...

EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal

11 Apr 2024

Contributed by Lukas

Join us as we welcome back Dr. Veera Rajagopal, a discovery scientist at Regeneron with an interest in human genetics and drug target discovery in neu...

EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy

04 Apr 2024

Contributed by Lukas

In this episode, Patrick welcomes Jean Swidler, the Founder, Executive Director, and Chair of End the Legacy. End the Legacy is a patient-led organiza...

EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata

28 Mar 2024

Contributed by Lukas

Join us as we welcome two familiar faces, Dr. James Beck, Chief Scientific Officer at Parkinson's Foundation, and Dr. Ignacio “Nacho” Mata, Profes...

EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin

21 Mar 2024

Contributed by Lukas

In this episode, Patrick is joined by Dr. Mazen Noureddin, Professor of Medicine and Transplant Hepatologist at Houston Methodist Hospital. Mazen also...

EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund

14 Mar 2024

Contributed by Lukas

In this episode, we welcome Julia Taravella, Executive Director of Rare Trait Hope Fund. She founded the organisation 11 years ago when her two childr...

EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy

07 Mar 2024

Contributed by Lukas

This week, we’re joined by Lord James O’Shaughnessy, Member of the House of Lords (UK), and Senior Partner at Newmarket Strategy. In May 2023, Lor...

EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews

29 Feb 2024

Contributed by Lukas

On Rare Disease Day, we’re joined by John Matthews, Chief Medical Officer at ReCode Therapeutics. John and Patrick discuss how ReCode is using lipid...

EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute

22 Feb 2024

Contributed by Lukas

This week we’re joined by Holly Peay, Senior Research Scientist in Bioethics and Genetic Counseling at the Research Triangle Institute (RTI), and Di...

EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome

15 Feb 2024

Contributed by Lukas

This week, we deep-dive into the world of genome engineering and yeast organisms with Leslie Mitchell. She’s the Co-founder and CEO of Neochromosome...

EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar

08 Feb 2024

Contributed by Lukas

Welcome to this episode of The Genetics Podcast as we host Dr. Michael Benatar, a preeminent figure in the fight against Amyotrophic Lateral Sclerosis...

EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology

01 Feb 2024

Contributed by Lukas

In this episode, we welcome Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology and former professor at University of California at San Francisco...

EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan

25 Jan 2024

Contributed by Lukas

This week we’re joined by the Director of the Neuroscience Data Science: Discovery & Molecular Group at Johnson and Johnson, and Chair of the UKBiob...

EP 118: The role of genetics in drug discovery and development with Dr. Matt Nelson

18 Jan 2024

Contributed by Lukas

Join Patrick as he welcomes Dr. Matt Nelson, an influential voice in the field of genetics and drug development. Matt is currently the Vice President ...

EP 117: Wendy Chung: whole genome newborn screening and other big opportunities in genomic medicine.

11 Jan 2024

Contributed by Lukas

In this episode we welcome Dr. Wendy Chung, Chair of the Department of Pediatrics at Boston Children’s Hospital and Professor at Harvard Medical Sch...

EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick

04 Jan 2024

Contributed by Lukas

Join us for our first episode of 2024 as we welcome Dr. Alex Bick, Assistant Professor of Medicine in the Division of Genetic Medicine at Vanderbilt U...

EP 115: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 2)

27 Dec 2023

Contributed by Lukas

In the second instalment of our annual round-up episode, we welcome back Dr. Veera Rajagopal to cover the biggest stories in genetics and precision me...

EP 114: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 1)

21 Dec 2023

Contributed by Lukas

In this annual round-up episode, we welcome back Dr. Veera Rajagopal to cover some of the biggest stories in genetics and precision medicine from 2023...

EP 113: Harnessing human genetics to discover co-evolved small molecule medicines with Dr. Jason Park, CEO of Empress Therapeutics

07 Dec 2023

Contributed by Lukas

In this episode of The Genetics Podcast, we welcome Dr. Jason, founder and CEO of Empress Therapeutics, a Flagship Pioneering company.

EP 112: Making the leap: the scientists collaborating to transform genetic targets into next generation treatments, with David Ochoa

23 Nov 2023

Contributed by Lukas

This week on The Genetics Podcast Patrick is joined by David Ochoa, Platform Coordinator at Open Targets. They discuss how the Open Targets platform i...

EP 111: Combining human and machine intelligence in protein engineering with Dr. James Field, CEO of LabGenius

09 Nov 2023

Contributed by Lukas

In this episode of The Genetics Podcast, we welcome Dr. James Field, founder and CEO of LabGenius. Join us as we delve into LabGenius' cutting-edge ap...

EP 110: Educating the next generation of genomics talent, and the intersection of genetics and environment in cancer with Barbara Kraatz Fortini

26 Oct 2023

Contributed by Lukas

On this episode of The Genetics Podcast we welcome Dr. Barbara Kraatz Fortini, Associate Professor of Genetics at Keck Graduate Institute (KGI). Tune ...

EP 109: From the Archives: Professor Sir Rory Collins on the Origins and Future of the UK Biobank

12 Oct 2023

Contributed by Lukas

This week, we’re re-sharing one of our favorite episodes from the early days of The Genetics Podcast - one that many newer listeners may not have he...

EP 108: Drug Development in Liver Disease: Breakthroughs, Challenges, and Insights with Dimitar Tonev

28 Sep 2023

Contributed by Lukas

In this episode of The Genetics Podcast, we're joined by Dimitar Tonev, an experienced drug development consultant specialising in Hepatology and Viro...

EP 107: Integrating Genomics and Individualised Medicine into the Mayo Clinic Healthcare System with Dr. Konstantinos Lazaridis

14 Sep 2023

Contributed by Lukas

In this episode of The Genetics Podcast, we welcome Dr. Konstantinos Lazaridis, the Executive Director of the Center for Individualized Medicine at th...

Ep 106: The Colliding World of Rare and Common Disease Genetics with Caroline Wright, Professor of Genomic Medicine at Exeter University

31 Aug 2023

Contributed by Lukas

In this episode, Patrick welcomes Caroline Wright, a leading expert in genomic medicine and Professor of Genomic Medicine at Exeter University. Listen...

EP105: Warren Huff, CEO and Chairman of Reata Pharmaceuticals, shares perspectives on provocative biology and the development of treatments for rare diseases

17 Aug 2023

Contributed by Lukas

In this episode, Patrick welcomes J. Warren Huff, CEO and Chairman of Reata Pharmaceuticals. Reata is known for innovating small-molecule therapies fo...

EP104: Assessing the clinical utility of Polygenic Risk Scores in cancer screening with Professor Clare Turnbull

04 Aug 2023

Contributed by Lukas

Join Patrick Short and Professor Clare Turnbull, Professor in Translational Cancer Genetics at the Institute of Cancer Research, as they discuss polyg...

EP103: Gene Writing with Tessera Therapeutics CEO, Dr. Mike Severino

20 Jul 2023

Contributed by Lukas

In this episode, Patrick is joined by Dr. Mike Severino, CEO of Tessera Therapeutics and CEO-Partner of Flagship Pioneering. Join us as Mike walks us ...

EP102: Dr. Marco Schmidt, founder and Chief Scientific Officer of BioTx.ai, on how to use artificial intelligence and machine learning in genomics research

06 Jul 2023

Contributed by Lukas

0:00 Intro 0:45 The founding of BioTx.ai 4:35 How do algorithms for ‘causal inference’ work? 6:30 Modeling gene interactions for genetic disord...

EP101: Fostering international progress towards personalised medicine with Dr. Bettina Lundgren, CEO of the Danish National Genome Center

22 Jun 2023

Contributed by Lukas

Join Patrick in welcoming Dr. Bettina Lundgren, CEO of the Danish National Genome Center. Bettina is spearheading the development of personalised medi...

EP100: Decoding DNA and engineering biology: perspectives on the future of genomics with Dr. Matthew Hurles, Director of the Wellcome Sanger Institute.

08 Jun 2023

Contributed by Lukas

In this milestone episode, we welcome Dr Matthew Hurles, geneticist and pioneer in the field of human genomics. Dr Hurles has dedicated his career to ...

EP99: Exploring the frontiers of cancer research with Dr. Harold E Varmus

25 May 2023

Contributed by Lukas

Join us for EP99 of The Genetics Podcast as Patrick dives into the extraordinary career and work of Dr. Harold E Varmus, a Nobel laureate scientist, f...

EP 98: Cancer, ageing, and somatic mutation variation across mammals with Alex Cagan (Wellcome Sanger Institute)

11 May 2023

Contributed by Lukas

In this episode, Patrick is joined by Alex Cagan, a Postdoctoral Fellow in the Cancer, Ageing and Somatic Mutation programme at the Wellcome Sanger In...

EP 97: Proteomics deep dive with Cindy Lawley (Olink)

26 Apr 2023

Contributed by Lukas

In this episode, Patrick is joined by Cindy Lawley, Senior Director of Population Health at Olink Proteomics and co-host of the Proteomics in Proximit...

EP 96: CEO of Montai Health, Margo Georgiadis, talks the intersection of nature and AI

13 Apr 2023

Contributed by Lukas

Food is medicine. And leveraging its power to heal isn’t a new concept. In fact, roughly 50% of all small-molecule medicines are derived from natu...

EP 95: Resharing Eric Topol on how Machine Learning & AI can Contribute to the Future of Healthcare

31 Mar 2023

Contributed by Lukas

Progress in AI is accelerating, and the potential in healthcare and precision medicine is enormous. In 2019, we had the pleasure of speaking with Dr...

EP 94: Alnylam’s Dr Paul Nioi on how genetics is used in drug target discovery

16 Mar 2023

Contributed by Lukas

“We’re pioneering the ability to detect genetic disease earlier, and actually intervene in a way that is going to help those patients.” In this...

EP 93: International Perspectives on Access to Genetic Testing in ALS

24 Jan 2023

Contributed by Lukas

Access to genetic testing for patients with genetic diseases, such as ALS, can vary dramatically based on country and postcode. For an ALS patient c...

EP 92: Four Predictions for 2023

05 Jan 2023

Contributed by Lukas

From changing drug pricing legislation to AI breakthroughs, in the first episode of The Genetics Podcast for 2023, Patrick makes four predictions for ...

EP 91: 2022 Genetics Round-up with Dr Veera Rajagopal

24 Dec 2022

Contributed by Lukas

If there’s one genetics podcast episode to listen to this year, it’s this one. In the final episode of The Genetics Podcast for 2022, we’re jo...

EP 90: Patient-centric drug development in ALS with Ronald van der Geest, Chief Development Officer of Treeway

08 Dec 2022

Contributed by Lukas

"If someone tells you it’s not possible, then it’s interesting" according to Treeway Chief Development Officer Ronald van der Geest. Fo...

EP 89: Baroness Nicola Blackwood on the UK's leading role in delivering 'genomic healthcare for everyone'

24 Nov 2022

Contributed by Lukas

This week Patrick is joined by Baroness Nicola Blackwood, the first female MP for Oxford. She was elected by MPs of all parties to Chair the Commons S...

EP 88: Precision oncology: how Next Generation Sequencing (NGS) is powering care today and the treatments of the future with Christine Ward (Takeda) and Geoff Oxnard (Foundation Medicine)

10 Nov 2022

Contributed by Lukas

In this episode, guests Christine Ward, VP and Head of Oncology and Cell Therapy Precision & Translational Medicine at Takeda and Geoff Oxnard, Th...

EP 87: Representation Matters: Why equitable access and community engagement are critical in genetic research

27 Oct 2022

Contributed by Lukas

This episode, our Partnerships Lead, Lindsey Wahlstrom-Edwards dove into the importance of representation in genetic research, covering the techniques...

EP 86: Heidi Rehm PhD, Chief Genomics Officer at Massachusetts General Hospital on curating and collaborating genomic datasets to guide the future of diagnostic and clinical research

13 Oct 2022

Contributed by Lukas

This week, Patrick speaks to Heidi Rehm, Chief Genomics Officer at Massachusetts General Hospital. Heidi is a leader in defining standards for the int...

EP 85: Dr Jessica Kissinger on large-scale parasite genomics and the power of multi-omic data

29 Sep 2022

Contributed by Lukas

Dr Jessica Kissinger and her collaborators run some of the world's largest databases of multi-omic data from eukaryotic parasites. In this episode...

EP 84: Mark Kotter, CEO, and Founder of bit.bio, on creating every cell type and kickstarting a cell therapy revolution

01 Sep 2022

Contributed by Lukas

Doctors have been transplanting organs for decades, but can we transplant reprogrammed stem cells to rejuvenate the human body? This week Patrick disc...

EP 83: Daphne Koller, Founder & CEO of Insitro - Integrating machine learning and biology at scale to reimagine drug discovery

11 Aug 2022

Contributed by Lukas

About this Episode: This week’s guest, Daphne Koller, is the Founder and CEO of Insitro - a company shifting the paradigm of new drug discovery usi...

EP 82: Lessons from the world's largest genomic datasets with Daniel MacArthur, Director of the Centre for Population Genomics.

13 Jul 2022

Contributed by Lukas

This week’s guest, Daniel MacArthur, is the Director of the Centre for Population Genomics at the Garvan Institute of Medical Research and Murdoch C...

EP 81: Cracking the druggable genome with Dietrich Stephan, Founder and CEO of NeuBase Therapeutics

29 Jun 2022

Contributed by Lukas

This week Patrick is joined by Dietrich Stephan, Founder and CEO of NeuBase Therapeutics. They discuss how to overcome the challenges of ’un-druggab...

EP 80: Rare disease genomics and the 'near-coding' genome with Nicky Whiffin, Group Leader at the Wellcome Centre for Human Genetics

15 Jun 2022

Contributed by Lukas

From decoding the genetics of rare disease using computational methods, to understanding the non-coding and 'near-coding' genome, this week Pa...

EP 79: The Unknown Causes of Kidney Disease Project with Michael Spigler, Vice President of Patient Support and Education at American Kidney Fund

01 Jun 2022

Contributed by Lukas

In this week’s episode Patrick is joined by Michael Spigler, Vice President of Patient Support and Education at American Kidney Fund. They discuss h...

EP 78: From datasets to front-line healthcare; polygenic risk scores and genomic prediction with Prof Sir Peter Donnelly, CEO of Genomics PLC

18 May 2022

Contributed by Lukas

This week Patrick is joined by Sir Peter Donnelly, CEO of Genomics PLC and Professor of Statistical Science at the University of Oxford. They discuss ...

EP 77: The journey to novel gene therapies for hearing loss and balance disorders with Laurence Reid, CEO at Decibel Therapeutics

04 May 2022

Contributed by Lukas

This week’s guest is Laurence Reid, CEO at Decibel Therapeutics. He talks to Patrick about the journey to deliver novel gene therapies to patients w...

EP 76: The UK Biobank Whole Genome Sequencing Project: building the future of genomics research with Dr Mark Effingham, Dr Kári Stefánsson and Professor Marylyn Ritchie

20 Apr 2022

Contributed by Lukas

This week Patrick is joined by three pioneering guests united by one ground-breaking project: the UK BioBank’s Whole Genome Sequencing Project. Dr M...

EP 75: Participant engagement in genomics research, with Nathalie Kingston, Director of the NIHR BioResource

06 Apr 2022

Contributed by Lukas

This week’s guest is Nathalie Kingston, Director of the NIHR BioResource. She talks to Patrick about how the scale of the BioResource has grown dram...

EP 74: Biggest breakthroughs of 2021 with Personalized Medicine Podcast host, Oleksandr Yagensky

19 Dec 2021

Contributed by Lukas

In the last episode of the year, Patrick joins forces with the host of the Personalized Medicine Podcast, Oleksandr Yagensky, to discuss six of the bi...

EP 73: Ochre Bio: Building an in-silico liver model and addressing the impact and challenges of developing new treatments

24 Nov 2021

Contributed by Lukas

In this week’s episode Patrick speaks to Quin Wills and Jack O’ Meara, Co-Founders of Ochre Bio, about their founding story, why in-silico discove...

EP72: The DecodeME team on the challenges facing myalgic encephalomyelitis and chronic fatigue syndrome patients and the future of personalised treatments

10 Nov 2021

Contributed by Lukas

In this week’s episode Patrick speaks to Sonya Chowdhury, Chris Ponting and Andy Devereux-Cooke from the DecodeME project, the world’s largest gen...

EP 71: Chief Medical Officer at LyGenesis, Professor Paulo Fontes, on the future of organ transplants

29 Oct 2021

Contributed by Lukas

This week’s guest, Paulo Fontes, is a Professor of Surgery and Chief Medical Officer at LyGenesis, an organ regeneration technology platform with a ...

EP 70: The University of Oxford's Professor Cecilia Lindgren: understanding complex disease through big data and team science

14 Oct 2021

Contributed by Lukas

In this week’s episode Patrick speaks to Director of the Big Data Institute at University of Oxford, Professor Cecilia Lindgren, about her biggest e...

EP 69: Chief Scientific Officer at Parkinson's Foundation, Dr James Beck, and Dr Ignacio Mata, Professor at the Cleveland Clinic, on the genetics of Parkinson’s disease and the future of precision treatments

24 Sep 2021

Contributed by Lukas

What is the role of genetics in Parkinson’s disease? From the impact of variants in the LRRK2 gene, to the need to expand PD research in diverse pop...

EP 68: Dr Patrick Short features on GIANT’s Healthy Innovators Podcast and discusses the path to creating a successful startup in genomic medicine

01 Sep 2021

Contributed by Lukas

In this special episode we’re sharing Patrick’s guest appearance on GIANT’s Healthy Innovators Podcast. He talks to the podcast’s host, Barry ...

EP 67: Dr Anna Lewis from the Edmond J. Safra Center for Ethics at Harvard, on the biggest ethical questions in DNA sequencing and editing

18 Aug 2021

Contributed by Lukas

As more and more people get their DNA sequenced, through health care initiatives, biobanks and direct-to-consumer testing, an array of ethical questi...

EP 66: Professor David Strain, Senior Clinical Lecturer at the University of Exeter Medical School, on the emergence of Long COVID, its impact and how research is vital for supporting patients

04 Aug 2021

Contributed by Lukas

For many Long COVID patients the debilitating long-term symptoms they experience emerged after what, at first, appeared to be a mild COVID-19 infectio...

EP 65: Dr Patrick Short guest features on The G Word podcast and discusses the power of translational research with CEO of Genomics England, Chris Wigley

30 Jun 2021

Contributed by Lukas

In this special episode we’re sharing Patrick’s guest appearance on Genomics England’s new podcast, The G Word. Patrick speaks to Chris Wigley, ...

Precision Pioneers EP 8: Chief Medical Officer at ESCAPE Bio, Dr Carrolee Barlow, on developing precision medicines for genetic forms of Parkinson’s disease

23 Jun 2021

Contributed by Lukas

How can precision medicine techniques be used to develop potential new treatments for genetic Parkinson’s disease? In the latest episode of our Prec...

Precision Pioneers EP 7: Dr Vineeta Agarwala on investing in the future of precision medicine at the a16z bio fund

07 Jun 2021

Contributed by Lukas

Can the speed and success of COVID-19 trials teach us how to run other trials 5x faster going forward? Can polygenic risk scores be effectively integr...

Precision Pioneers EP 6: Chief Medical Officer at ASC Therapeutics, Oscar Segurado, on the break-through application of CRISPR gene editing to treat haemophilia

19 May 2021

Contributed by Lukas

What have gene editing and gene therapies got to do with rockets and satellites? Oscar Segurado, Chief Medical Officer at ASC Therapeutics, explains i...

Precision Pioneers EP 5: Alnylam's Josh Friedman on developing precision medicines for the 'silent killer' NASH/NAFLD

05 May 2021

Contributed by Lukas

On this episode of the podcast, Patrick is joined by Josh Friedman, Senior Director of Research at Alnylam Pharmaceuticals. Alnylam works on the disco...

Precision Pioneers EP 4: Geneticist and Harvard professor, Robert Green on accelerating implementation of genomic medicine

21 Apr 2021

Contributed by Lukas

On this episode of the podcast Patrick is joined by Robert Green, a geneticist, Professor of Medicine at Harvard, and Director of the Preventive Genom...

Precision Pioneers EP 3: CEO of Faze Medicines, Phil Vickers on 'Running toward challenges' in precision medicine development

07 Apr 2021

Contributed by Lukas

Continuing with our mini series of Precision Pioneers, Patrick is joined by Phil Vickers, President and CEO at Faze Medicines. Phil discusses his care...

Precision Pioneers EP 2 : Aristea Therapeutics CMO Nihar Bhakta on developing precision medicines for both common and rare diseases

25 Mar 2021

Contributed by Lukas

This week Patrick talks to Nihar Bhakta as part of our series of ‘Precision Pioneers’. Dr Bhakta is the Chief Medical Officer at Aristea Therapeut...

Precision Pioneers EP 1: Variant Bio CSO Kaja Wasik on the power of human genetic diversity in drug development

03 Mar 2021

Contributed by Lukas

This week Patrick is joined by Dr Kaja Wasik, CSO and co-founder of Variant Bio. Prior to Variant Bio, Kaja co-founded Gencove, a spin-out from the Ne...

EP 56: The business of start ups with Jason Mellad, CEO of Start Codon

17 Feb 2021

Contributed by Lukas

On this episode, Patrick is joined by Jason Mellad, CEO and Co-Founder at Start Codon, a healthcare startup accelerator that helps develop healthcare ...

EP 55: The Girl With MS talks about her journey with Multiple Sclerosis and advocacy

03 Feb 2021

Contributed by Lukas

This week we talk to ‘The Girl With MS’, Caroline Craven. A Multiple Sclerosis patient advocate, Caroline has written thousands of blog posts abou...

Ep 54: Genetic testing, breaking down stigma, and supporting people with Familial ALS with Daniel Barvin

20 Jan 2021

Contributed by Lukas

In this episode of the Genetics Podcast we’re joined by Daniel Barvin, an ALS advocate whose family is affected by Familial ALS. Daniel has a gene...

EP 53: Predictions and trends to watch for the year ahead with Jane Theaker, Phillip Beer, and Jason Mellad

14 Jan 2021

Contributed by Lukas

This first episode of 2021 sees host Patrick Short talk to three insightful guests about their predictions for research and medicine in the year ahead...

EP 52: Population-scale viral sequencing with Dr Jeff Barrett, Lead Statistical Geneticist for COG-UK

09 Dec 2020

Contributed by Lukas

On this episode of the podcast Patrick is joined by returning guest Dr Jeff Barrett. Jeff is the the lead statistical geneticist for The COVID-19 Geno...

EP 51: 20-year study of 55,000 Canadians: Alberta's Tomorrow Project with Dr Jennifer Vena

26 Nov 2020

Contributed by Lukas

On this episode of the podcast Patrick is joined by Dr Jennifer Vena the Scientific Director of Alberta’s Tomorrow Project. Although Jennifer joined...

EP 50: Dr Barry Singer, the MS doctor who is using technology to connect with patients and scale his impact

11 Nov 2020

Contributed by Lukas

Dr Barry Singer is a neurologist who specialises in multiple sclerosis, he is also the host of MS Living Well, a podcast that deals with living with m...

EP 49: Genomics in education and the social sciences with Dr Daphne Martschenko

29 Oct 2020

Contributed by Lukas

Patrick interviews Dr Daphne Martschenko, a postdoctoral research fellow at Stanford University. Daphne’s work has focused on genomics and the Ameri...

EP 48: Tipping the Balance on Ulcerative Colitis with Seb Tucknott

14 Oct 2020

Contributed by Lukas

Seb Tucknott is an author and patient advocate who was diagnosed with Ulcerative Colitis in 2008. In 2015 he founded IBD relief, an online community o...

EP 47: HDR-UK CEO Caroline Cake: Making the UK a world leader in health data science

30 Sep 2020

Contributed by Lukas

Chief Executive Officer of Health Data Research UK Caroline Cake joins Patrick to talk about accelerating medical research through health data science...

EP 46: Rebel Cell: Kat Arney's new book on Cancer, Evolution, and the Science of Life

16 Sep 2020

Contributed by Lukas

Kat Arney returns to the podcast to discuss her new book ‘Rebel Cell’, which takes an evolutionary look at cancer. Kat talks about the book begin...

EP 45 Steff Di Pardo on Ankylosing Spondylitis and Instagram as a support network for health communities

02 Sep 2020

Contributed by Lukas

This week we talk to Steff Di Pardo, a patient advocate and writer who has Ankylosing Spondylitis - which is a chronic autoimmune disease. She talks a...

EP 44 Bringing preventive health to 8 billion people: Peter Würtz from Nightingale Health on their pioneering blood testing platform

19 Aug 2020

Contributed by Lukas

We talk to Peter about Nightingale Health's work with the UK Biobank, including recent research that shows their blood test could be used predict ...

EP 43 Diversity in clinical research and COVID19's impact on people with immune conditions with Dr Sonya Abraham.

05 Aug 2020

Contributed by Lukas

Sonya Abraham is a clinical senior lecturer in rheumatology and a research physician at Imperial College London. We talk to her about BAME representat...

EP 42 Tapoka Mkandawire on the gut microbiome, neglected tropical diseases, and the power of citizen science

29 Jul 2020

Contributed by Lukas

Tapoka Mkandawire is a PhD student in parasitology & genomics at the Wellcome Sanger Institute. She studies neglected tropical diseases, which aff...

EP 41 Keith McArthur, the rare disease dad who is re-writing the rules in order to find a cure for his son - Live Podcast

25 Jul 2020

Contributed by Lukas

Keith McArthur is one of the parents re-writing the rules for research in rare disease. Keith is CEO of the CureGRIN foundation, a non-profit backed b...

EP 40 Professor Sir Rory Collins on the origins and future of the UKBiobank

23 Jul 2020

Contributed by Lukas

Professor Sir Rory Collins, Founder and Chief Executive of the UK Biobank, talks to us this week about the origins of this world-changing project that...

Ep 39 How hundreds of scientists from 50 nations are collaborating on Slack to study genetics & COVID19 with Dr Andrea Ganna

09 Jul 2020

Contributed by Lukas

Andrea Ganna has been leading COVID19HG, a worldwide effort to understand the role that our genetics plays in COVID-19 infection and severity. In this...

EP 38: Big Data in genomics - why we need 'the cloud' and AI to make sense of it all with Dr Maria Chatzou Dunford

30 Jun 2020

Contributed by Lukas

Genomic data, is big data - so how do we actually make sense of this huge amount of data? And why should we use 'the cloud’ to store and analyse...

EP 37: The future of medical research post COVID

10 Jun 2020

Contributed by Lukas

This episode covers some of the dramatic changes in the field of medical research as a result of COVID19 making it unsafe for people to visit medical ...

EP 36: Genomics England CEO Chris Wigley & Clinical Lead Richard Scott: sequencing 35,000 people with COVID19, the future of genomic medicine, and why patients are their 'north star'

27 May 2020

Contributed by Lukas

Why do some people have a severe response to COVID-19, and others seem to have no symptoms at all? Is the answer in our genes? This week we talk to C...

EP 35: 8 weeks in - what it’s like to have COVID-19 with Adelina Chalmers

13 May 2020

Contributed by Lukas

This week we talk about COVID19 and what it’s really like to have the virus. Talking to Adelina Chalmers, who first started experiencing symptoms 8 ...

EP 34: 1 in 70 million - conversation with rare disease advocate David Rose

29 Apr 2020

Contributed by Lukas

What’s it like having a disease so rare, you’re misdiagnosed? Or you’re the only one in the whole of the UK to have it? David Rose is a rare d...