The Scientist’s LabTalk
Activity Overview
Episode publication activity over the past year
Episodes
Synthetic Screens, Genes, and De Novo Proteins: Training AI Models with More Sequence Diversity to Improve Hits
17 Sep 2024
Contributed by Lukas
Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutio...
Synthetic Screens, Genes, and De Novo Proteins: Multiplexed Gene Fragments Drive De Novo Protein Design
03 Sep 2024
Contributed by Lukas
Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutio...
Synthetic Screens, Genes, and De Novo Proteins: Engineering Gene Regulation through Creative Experimental Design
20 Aug 2024
Contributed by Lukas
Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutio...
Science Philosophy in a Flash: Demystifying Cell Culture Through Oxygen Analysis
01 Jul 2024
Contributed by Lukas
With a track record of invention and translating technology into practical solutions, Walker Inman continues to drive innovation in the life sciences ...
Science Philosophy in a Flash: Curiosity and Compassion Fuel Rare Disease Research
02 Jan 2024
Contributed by Lukas
Lauren Drouin is the director of analytical development and the Genomic Medicine Unit at Alexion AstraZeneca Rare Disease. As a dynamic scientist with...
Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering
20 Dec 2023
Contributed by Lukas
Researchers commonly employ lentiviruses to modify cells genetically. However, they must overcome several challenges when using these viruses in the l...
Molecular Diagnostics: An Eye Toward the Future - Real Time Diagnostics: Improving HPV Screening with PCR
24 Oct 2023
Contributed by Lukas
Scientists continuously develop new assays to fill unmet diagnostic needs. While methods such as quantitative PCR have emerged as essential tools in m...
Molecular Diagnostics: An Eye Toward the Future - Considerations for Oncology Biomarker Testing
29 Aug 2023
Contributed by Lukas
Scientists continuously develop new assays to fill unmet diagnostic needs. While methods such as quantitative PCR have emerged as essential tools in m...
Molecular Diagnostics: An Eye Toward the Future - Modernizing Molecular Diagnostics, from Assay Development to Routine Testing
27 Jun 2023
Contributed by Lukas
Scientists commonly use qPCR applications in molecular diagnostics to detect pathogens, assess viral loads, or uncover mutations. While the qPCR assay...
Molecular Diagnostics: An Eye Toward the Future - The Simple Solution of Saliva
31 May 2023
Contributed by Lukas
Welcome to Molecular Diagnostics: An Eye Toward the Future, a special edition podcast series produced by The Scientist’s Creative Services Team. Thi...
Building Bridges for Translational Research - Supporting mRNA Therapeutic Development and Beyond
19 Apr 2023
Contributed by Lukas
Translational research cannot be conducted in a vacuum. For a translational researcher to be successful, they need to build strong relationships with ...
Building Bridges for Translational Research - Bringing Gene Therapy Closer to the Clinic
12 Apr 2023
Contributed by Lukas
In this episode, Guangping Gao, professor and director of the Horae Gene Therapy Center at the University of Massachusetts Medical School, speaks abou...
Building Bridges for Translational Research - The Secrets to Start-Up Success
05 Apr 2023
Contributed by Lukas
Welcome to Building Bridges for Translational Research, a special edition podcast series produced by The Scientist’s Creative Services Team. This se...
Understanding the Blood Cancer Genomic Landscape
13 Dec 2022
Contributed by Lukas
Immunotherapies are promising as a holy grail for cancer treatment, but patient responses to these interventions are often variable in both solid tumo...
Exposed: Environmental Echoes in Health - How Toxins Leave Their Cancerous Marks
19 Oct 2022
Contributed by Lukas
Through epigenetic mechanisms, some environmental toxicants, such as heavy metals, reversibly alter gene expression patterns that then drive cancer pr...
Exposed: Environmental Echoes in Health - Are We What Our Parents Eat?
12 Oct 2022
Contributed by Lukas
Substances that enter the body, such as food or chemicals, can make epigenetic changes in the germline that become inherited, affecting the health of ...
Exposed: Environmental Echoes in Health - Epigeneticist Turned Microbe Hunter
05 Oct 2022
Contributed by Lukas
Welcome to Exposed: Environmental Echoes in Health, a special edition podcast series produced by The Scientist’s Creative Services Team. This series...
The New Era of Neurodegeneration Research
28 Sep 2022
Contributed by Lukas
The brain’s intractable nature makes neurodegenerative disorders challenging to study, but modern assays and technologies give scientists a fresh lo...
Transporting Laboratories into the Future with Smart Technology
23 May 2022
Contributed by Lukas
As smart devices become commonplace in many homes, they also enter life science laboratories with the promise to enhance productivity, simplify collab...
Phagocidal Macrophages: A New Battle Tactic Against Resistant Cancers
29 Nov 2021
Contributed by Lukas
Cancer immunotherapies are saving lives, but researchers still have a long journey ahead of them. Many cancers that are initially sensitive to immunot...
Hijacking Genes: Uncovering the Cause of Lineage Ambiguous Leukemia
31 Oct 2021
Contributed by Lukas
Childhood cancer is devastating. Every year over 15,000 children in the United States are diagnosed with cancer, with leukemia accounting for 28% of a...
Understanding Microglial Response in Alzheimer’s Disease
31 Jul 2021
Contributed by Lukas
A diverse population of microglial cells resides in the brain. Similar to immune cells, microglial cells respond to minute changes in their environmen...
The Promise of Spatial Transcriptomics in Exploring Chronic Liver Disease
30 Jun 2021
Contributed by Lukas
The liver performs approximately 500 separate functions in the human body. With liver disease on the rise, scientists are developing treatments to sav...
Discovering the Secrets of Motor Neurons with Single Cell Sequencing
05 May 2021
Contributed by Lukas
Motor neurons originating in the spine control both voluntary and involuntary movements. Even though they have an essential function, they are notorio...
A Modern Trojan Horse: Delivering Combination Immunotherapies to Solid Tumors
28 Apr 2021
Contributed by Lukas
Chimeric antigen receptor (CAR) T cell immunotherapies hold great promise for cancer treatment, but they are not very effective against solid tumors. ...
Bugs with Drugs: Repurposing a Pathogenic Bacteria’s Weapon
17 Apr 2021
Contributed by Lukas
LabTalk is a special edition podcast produced by The Scientist’s Creative Services Team, where we explore topics at the leading edge of innovative r...
Predicting the Immune Response with Single-Cell Analysis: Autoimmunity, Vaccination, and COVID-19
31 Mar 2021
Contributed by Lukas
The human immune system is highly complex and variable. Some people mount robust responses to infection, vaccination, or immunotherapy, while others f...
The Past, Present, and Future of Gene Therapy: How to Scale-up Successfully
11 Dec 2020
Contributed by Lukas
The Scientist’s LabTalk is a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the leading edg...
Halting the Tuberculosis Epidemic with Research and Diagnostics: A Conversation with David Alland
13 Nov 2020
Contributed by Lukas
Welcome to The Scientist’s LabTalk, a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the le...
Surviving Stress: The Mysteries of Neuronal Survival and Neurodegeneration
20 Oct 2020
Contributed by Lukas
Welcome to The Scientist’s LabTalk, a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the le...
Myeloid Cells in Cancer and Science Advocacy: A Conversation with Miriam Merad
10 Sep 2020
Contributed by Lukas
Welcome to The Scientist’s LabTalk, a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the le...