The Shkreli Pill
Episodes
Episode 894: New Oral PGL-1 Breakthrough! Advanced Transcript on Godel
08 Jan 2026
Contributed by Lukas
In this episode, Martin discusses developments around a potential oral PGL-1 breakthrough and what it could mean for the broader biotech landscape. He...
Episode 893: Private Equity Already Bought Into the Next Nvidia. What Comes Next for AI Stocks
08 Jan 2026
Contributed by Lukas
In this episode, Martin discusses why he believes private equity has already positioned itself in what could become the next Nvidia. He examines what ...
Bonus: A Conversation with Martin Shkreli (starts at 2'05)
23 Dec 2025
Contributed by Lukas
Panel: Martin Shkreli, Adrian Dittmann, OutaRecorded on 12/23/2025
Episode 892: SEC Closed My Trading Account. I'm Not Done w CAPR. Intel Stock, Photonic Comp.
08 Dec 2025
Contributed by Lukas
In this episode, Martin recounts his claim that the SEC restricted his trading account and discusses how this affects his ability to manage positions ...
Episode 891: I Blew Up My Account & Had to Change Jobs. CAPR Stock Short Squeeze Aftermath
06 Dec 2025
Contributed by Lukas
In this episode, Martin describes how a major trading setback forced him to rethink his approach and pivot professionally. He walks through what happe...
Episode 890: AAA Bonds vs The Market. Who Wins？ Valuating Astra Zeneca Pipeline
04 Dec 2025
Contributed by Lukas
In this episode, Martin compares the stability of AAA bonds with the current state of the broader market, explaining how risk-adjusted returns stack u...
Episode 889: 2 BIG Potentials! Astra Zeneca DEEP Analysis. AZN Stock Drug Portfolio Analysis
04 Dec 2025
Contributed by Lukas
In this episode, Martin takes a deep look at AstraZeneca, highlighting two major areas of potential he sees within the company’s long-term strategy....
Episode 888: Google Even Higher on TPU Play, Novo Nordisk Facing Weak Forecast, Stock Analysis
03 Dec 2025
Contributed by Lukas
In this episode, Martin examines Google’s continued momentum, focusing on how its TPU strategy is driving renewed market optimism. He also reviews a...
Episode 887: Warming Up for Another Rally. My Safest Long, CAPR Crash Incoming, Nvidia, IonQ Stock Martin Shkreli
24 Nov 2025
Contributed by Lukas
In this episode, Martin explains why he thinks the market may be setting up for another rally and identifies what he considers his safest long positio...
Episode 886: Santa Claus Rally？ My Take on Overspending, OpenAI, Bubble Popping
22 Nov 2025
Contributed by Lukas
In this episode, Martin weighs in on whether a Santa Claus rally is possible amid growing signs of market strain. He discusses consumer overspending, ...
Episode 885: Five Rules Predict Nvidia and the Market. Semiconductor Peak Cycle？ My Forecast
21 Nov 2025
Contributed by Lukas
In this episode, Martin outlines five guiding rules he uses to anticipate major market turns, applying them specifically to Nvidia’s current positio...
Episode 884: Bear Market Is Here. Nvidia Earnings Analysis, Forecast, Agios Stock Long？
21 Nov 2025
Contributed by Lukas
In this episode, Martin explains why he believes a true bear market has arrived and breaks down Nvidia’s latest earnings to assess how the company m...
Episode 883: Turns Out the Nvidia Bear Isn’t So Crazy. United Therapeutics, Encoded Stock
20 Nov 2025
Contributed by Lukas
In this episode, Martin revisits the bearish case against Nvidia and explains why some of the skepticism may be more reasonable than it first appeared...
Episode 882: Nvidia Earnings Can’t Save This Market Crash. CoreWeave Deep Analysis CRWV Stock
19 Nov 2025
Contributed by Lukas
In this episode, Martin argues that even strong Nvidia earnings won’t be enough to stabilize a market he believes is heading for a deeper decline. H...
Episode 881: Biotech Investors Brace for the Real Threat ｜ End of Pharma ｜ AVXL Erasing Data
18 Nov 2025
Contributed by Lukas
In this episode, Martin discusses what he views as a major emerging threat for biotech investors and how it could reshape the pharmaceutical landscape...
Episode 880: Martin Shkreli Gives Away Investing Knowledge People Pay Big Money For I COMPILATION
17 Nov 2025
Contributed by Lukas
In this compilation episode, Martin shares some of his most valuable investing lessons and insights—concepts that he says many people pay large sums...
Episode 879: Quick! AVXL Short Isn’t Done Paying! Reaction to Anavex Stock News
16 Nov 2025
Contributed by Lukas
In this episode, Martin reacts to the latest news surrounding Anavex (AVXL) and explains why he believes the short trade may still have room to run. H...
Episode 878: Compensations Tell Short Sellers Everything ｜ Anavex Stock： Exposing Faked Trial
15 Nov 2025
Contributed by Lukas
In this episode, Martin discusses how executive compensation structures can inform short sellers about a company’s priorities and potential red flag...
Episode 877: I'm Going for 1000% YTD Gains. Shorting Anavex, $AVXL Stock, Exposing Scam Trial
15 Nov 2025
Contributed by Lukas
In this episode, Martin sets his sights on achieving 1000% year-to-date gains and outlines the high-risk trades he’s taking to reach that goal. He d...
Episode 876: How I'm Selling CAPR, Sarepta Stock Recovery Trade, Sam Altman, Burning Apes
13 Nov 2025
Contributed by Lukas
In this episode, Martin explains his strategy for selling CAPR and managing his ongoing Sarepta recovery trade. He also discusses recent developments ...
Episode 875: Buffett’s Last Letter to Shareholders： What It Really Means
12 Nov 2025
Contributed by Lukas
In this episode, Martin reviews Warren Buffett’s final letter to Berkshire Hathaway shareholders, interpreting its deeper meaning for investors and ...
Episode 874: Microsoft Still Hasn’t Paid Coreweave’s Bills! CAPR, CRWV Earnings Analysis
12 Nov 2025
Contributed by Lukas
In this episode, Martin discusses reports that Microsoft still hasn’t paid its outstanding bills to Coreweave and what that could mean for both comp...
Episode 873: Tomorrow, Fundamental Investors Take Over. Let Me Show Why. ｜ COMPILATION
10 Nov 2025
Contributed by Lukas
In this compilation episode, Martin argues that a shift toward fundamental investing is imminent and demonstrates the reasoning behind his view. Throu...
Episode 872: Forgotten Logic of Growth Stock Valuations： Tesla, Palantir, Duolingo, Google
09 Nov 2025
Contributed by Lukas
In this episode, Martin revisits the core principles behind growth stock valuations and argues that many investors have forgotten the logic that once ...
Episode 871: PLTR Calls Degenerate Gamble, DUOLingo Stock： Good But Risky, Biohaven
08 Nov 2025
Contributed by Lukas
In this episode, Martin critiques the surge in Palantir (PLTR) call options, calling it a degenerate gamble detached from fundamentals. He evaluates D...
Episode 870: +477% Gains. Here's My Full Trading Record! All In on Biohaven Stock, IONQ Earnings
07 Nov 2025
Contributed by Lukas
In this episode, Martin reveals his full trading record, showing how he achieved a 477% gain and the key moves behind his performance. He explains why...
Episode 869: How I Trade Sarepta, AMD & SMCI Earnings, Hating on Burry, AMGN Stock Review
06 Nov 2025
Contributed by Lukas
In this episode, Martin breaks down his trading approach to Sarepta and reviews the latest earnings reports from AMD and Super Micro Computer (SMCI). ...
Episode 868: Making Money in a Bear Market Is Easy. QURE Forecast, Trading Sarepta, Palantir
06 Nov 2025
Contributed by Lukas
In this episode, Martin explains why he believes making money in a bear market can be straightforward with the right strategy. He shares his latest fo...
Episode 867: One FDA Hint Skyrockets QURE Stock. SPRB： $500 When？ ｜ Uniqure, UnitedHealth Stock
05 Nov 2025
Contributed by Lukas
In this episode, Martin examines how a single FDA-related hint caused QURE stock to surge and what it reveals about market sensitivity to biotech news...
Episode 866: Sarepta Now 40% of My Portfolio. QURE Stock Crash, Biohaven Forecast, Palantir Bubble Martin Shkreli
05 Nov 2025
Contributed by Lukas
In this episode, Martin shares that Sarepta has grown to represent 40% of his portfolio and explains the reasoning behind his conviction. He discusses...
Episode 865: Walmart Valuation Signals Hoard Cash NOW. Reddit Stock Earnings is a Warning
04 Nov 2025
Contributed by Lukas
In this episode, Martin analyzes Walmart’s valuation and explains why he believes it signals a broader market shift toward caution and liquidity. He...
Episode 864: Berkshire Now Has $382 Billion in Cash. Good Luck. ｜ INVESTING GEMS COMPILATION
03 Nov 2025
Contributed by Lukas
In this episode, Martin examines Berkshire Hathaway’s record $382 billion cash position and what it signals about market sentiment and opportunity. ...
Episode 863: Which Meme Stock I’m Long？ Taiwan Semiconductor Analysis, Tesla, Apple Stock
02 Nov 2025
Contributed by Lukas
In this episode, Martin reveals which meme stock he’s currently long on and explains the reasoning behind the position. He also provides an analysis...
Episode 862: Nothing is Safe Anymore. Biohaven 3x Potential, Berkshire Stock Analysis, Apple, Meta Martin Shkreli
01 Nov 2025
Contributed by Lukas
In this episode, Martin reflects on growing market uncertainty and the idea that “nothing is safe anymore.” He highlights why he sees Biohaven as ...
Episode 861: Is Meta a No-Brainer Buy Right Now？ Google, Apple, Nvidia Stock Forecast
31 Oct 2025
Contributed by Lukas
In this episode, Martin evaluates whether Meta has become a clear buying opportunity at its current valuation. He compares Meta’s positioning to Goo...
Episode 860: Intel’s History Reveals Nvidia’s Path： Here’s What Worries Me. Stock Analysis, SPRB
31 Oct 2025
Contributed by Lukas
In this episode, Martin draws parallels between Intel’s historical rise and Nvidia’s current trajectory, highlighting the patterns that concern hi...
Episode 859: Time to Get Ready. My Options Trade on CAPR, Summit Stock Data, Nvidia Quantum
30 Oct 2025
Contributed by Lukas
In this episode, Martin discusses his latest options trade on CAPR and how he’s positioning ahead of potential market moves. He reviews new data rel...
Episode 858: New BTQ Contract News Made Martin Worried.. Quantum, Elliptic curve & Bitcoin
29 Oct 2025
Contributed by Lukas
In this episode, Martin reacts to new BTQ contract developments that have raised concerns about his position. He discusses the implications of the new...
Episode 857: Intellia: It's Not Looking Good. CAPR Short Around the Corner, Summit Stock Analysis
29 Oct 2025
Contributed by Lukas
In this episode, Martin reviews Intellia’s recent performance and explains why the outlook doesn’t appear promising. He discusses his upcoming sho...
Episode 856: Watch This Korean Stock Closely. I’m Bullish on RVMD, Nvidia AI GPU, Nassim Taleb
28 Oct 2025
Contributed by Lukas
In this episode, Martin points to a Korean stock he believes deserves close attention and explains why he’s bullish on RVMD and Nvidia’s AI GPU po...
Episode 855: What Is an Asset Now？ One Buffett Rule to Survive the Bubble. Why I Avoid Options
26 Oct 2025
Contributed by Lukas
In this episode, Martin explores how the definition of an asset has shifted in today’s market environment and what that means for investors navigati...
Episode 854: Tiger Cub’s Invincible Trading Approach. Palantir Isn’t Tech - It's a Hedge Fund
26 Oct 2025
Contributed by Lukas
In this episode, Martin analyzes the “Tiger Cub” style of investing, explaining why their trading approach has appeared nearly invincible in certa...
Episode 853: There’s a Whole Undervalued Market, Hurry Up. Shorting Tesla, Buffett, BYND Stock
25 Oct 2025
Contributed by Lukas
In this episode, Martin argues that there’s a largely overlooked segment of the market presenting strong value opportunities and urges investors to ...
Episode 852: Martin Bets $5K with a Retail Trader Then Quits Streaming. Gems on Covering Shorts
25 Oct 2025
Contributed by Lukas
In this episode, Martin makes a spontaneous $5,000 bet with a retail trader during a live stream and later announces his decision to step away from st...
Episode 851: Google Drops Quantum Surprise. Was Charlie Munger Wrong？ Cramer as a Trader. SPRB
25 Oct 2025
Contributed by Lukas
In this episode, Martin reacts to Google’s unexpected announcement related to Quantum and examines its implications for the tech and AI sectors. He ...
Episode 850: I'm Up 386%. Guess Why？ My Portfolio, BYND Stock Trade, Natera, Bitcoin, Quantum
25 Oct 2025
Contributed by Lukas
In this episode, Martin reveals that his portfolio is up 386% and breaks down the trades and strategies that led to this result. He discusses his posi...
Episode 849: The Next GME Is Here! Here's My Perfect Short Setup ｜ BYND Stock Beyond Meat Pump
25 Oct 2025
Contributed by Lukas
In this episode, Martin claims that the next GameStop-style setup has arrived and walks through what he calls his “perfect short” strategy. He ana...
Episode 848: The Real Reason Beyond Meat Stock is Pumping ｜ Martin Shkreli vs BYND Community Debate
25 Oct 2025
Contributed by Lukas
In this episode, Martin breaks down what he believes is the real reason behind the recent surge in Beyond Meat’s stock price. He also engages in a l...
Episode 847: Koreans Turned to Beyond Meat. TOP IS IN! New Long？ RVMD Revolution Medicines Stock
22 Oct 2025
Contributed by Lukas
In this episode, Martin comments on a surprising market trend involving Korean investors turning to Beyond Meat and argues that it could signal a mark...
Episode 846: Bubbles Do One Thing Before They Pop. Let Me Show You ｜ INVESTING COMPILATION
20 Oct 2025
Contributed by Lukas
In this compilation episode, Martin walks through historic and current market bubbles, focusing on the patterns he believes consistently appear right ...
Episode 845: Martin Turned to Real Estate. The End. ｜ IDEAYA Biosciences Stock Long
18 Oct 2025
Contributed by Lukas
In this episode, Martin discusses his shift toward real estate investing and reflects on what that transition means for his trading journey. He also a...
Episode 844: Still Holding Nvidia？ Energy Markets Handling AI Load, OKLO Stock. More Biotech Scams Martin Shkreli
17 Oct 2025
Contributed by Lukas
In this episode, Martin discusses whether it still makes sense to hold Nvidia amid shifting market dynamics. He explores how energy markets are adapti...
Episode 843: Gaslighting My Wife Again to Keep My Margin Account Alive ｜ Quantum Run
16 Oct 2025
Contributed by Lukas
In this episode, Martin humorously recounts the personal and financial stress of maintaining his margin account during the ongoing Quantum run. Blendi...
Episode 842: Quantum Run Got Me. SPRB & CAPR is All I Have ｜ Bitcoin Supply ｜ JNJ, ATYR Stock
16 Oct 2025
Contributed by Lukas
In this episode, Martin reflects on the impact of the Quantum run on his portfolio and discusses how SPRB and CAPR have become his main remaining posi...
Episode 841: It Was Over for Lil Man Before It Even Started ｜ Martin Shkreli Funny Livestream Moments
15 Oct 2025
Contributed by Lukas
In this highlight compilation, Martin showcases some of the funniest and most unexpected moments from his livestreams. Featuring quick wit, audience i...
Episode 840: Motley Fool Guy Gets Emotional over Martin Taking him to School
12 Oct 2025
Contributed by Lukas
In this episode, Martin debates a guest known as the “Motley Fool Guy,” whose reactions grow increasingly emotional as Martin challenges his argum...
Episode 839: " I Short Fraud and Hype ". The Capital Cycle Guy Gets Mad & Fights Back
12 Oct 2025
Contributed by Lukas
In this episode, Martin doubles down on his philosophy of shorting what he calls “fraud and hype” in the markets. The Capital Cycle Guy pushes bac...
Episode 838: Capital Cycle Guy Confronts Martin on His Short Thesis. Things Get Heated
12 Oct 2025
Contributed by Lukas
In this episode, Martin is confronted by the “Capital Cycle Guy,” who challenges his short thesis in a tense and candid exchange. The discussion d...
Episode 837: Applovin Stock is Getting to Me. How to Test Your Technical Analysis Theory
11 Oct 2025
Contributed by Lukas
In this episode, Martin discusses his evolving thoughts on Applovin stock and the emotional challenges that can come with holding or trading it. He al...
Episode 836: AMD Stock Deep Analysis & Conclusion. What Their OpenAI Chip Deal Actually Is ?
11 Oct 2025
Contributed by Lukas
In this episode, Martin presents an in-depth analysis of AMD stock, breaking down the company’s fundamentals, valuation, and market position. He als...
Episode 835: Spruce Stock Has More Upside, How Rare Disease Drugs Stay Profitable, CAPR Short
10 Oct 2025
Contributed by Lukas
In this episode, Martin explains why he believes Spruce stock still has room for further gains and discusses what makes rare disease drugs maintain pr...
Episode 834: My Next Short Trade： BTQ Stock. Enzyme Replacement Therapy Origins Explained
10 Oct 2025
Contributed by Lukas
In this episode, Martin outlines his next short trade, focusing on BTQ stock and the reasoning behind his position. He also takes a step back to expla...
Episode 833: Why My Prediction AI Suddenly Went Long CAT Stock？ QURE Stock, Books to Read
09 Oct 2025
Contributed by Lukas
In this episode, Martin explains why his prediction AI unexpectedly shifted to a long position on CAT stock and what factors may have driven the chang...
Episode 832: I'm Down Again. How I Knew Spruce Stock Would 7x, Books to Read, Career Advice
09 Oct 2025
Contributed by Lukas
In this episode, Martin reflects on recent market losses and explains how he identified the setup that led to Spruce stock’s sevenfold increase. He ...
Episode 831: A MIRACLE! BREAKTHROUGH Drug Forecast & Analysis. Spruce Biosciences Stock
08 Oct 2025
Contributed by Lukas
In this episode, Martin highlights what he describes as a breakthrough drug development and offers his forecast and analysis of its potential impact. ...
Episode 830: OpenAI & AMD Deal is Too Suspicious. Ambarella & Monopar therapeutics Analysis
08 Oct 2025
Contributed by Lukas
In this episode, Martin examines a deal between OpenAI and AMD that he views as unusually suspicious, exploring its possible implications for the mark...
Episode 829: You Thought This Was Over, Huh？ Let's Get You Ready ｜ BEST OF COMPILATION
06 Oct 2025
Contributed by Lukas
In this episode, Martin presents a special “Best Of” compilation, revisiting key moments, insights, and lessons from previous streams. He highligh...
Episode 828: Shorting GPU Providers is The Next Big Move. Prizes for Best Godel Trader!
05 Oct 2025
Contributed by Lukas
In this episode, Martin discusses why he believes shorting GPU providers could be the next major opportunity in the market and explores the factors dr...
Episode 827: EA Historical Takeover Explained. Rigetti Positive News Didn't Move the Stock
02 Oct 2025
Contributed by Lukas
In this episode, Martin walks through the history of EA’s notable takeover and the broader lessons it offers for investors. He also looks at recent ...
Episode 826: Still the Easiest Short And I’m Not Talking IonQ. ＂Big＂ IBM News, Soundhound Stock
01 Oct 2025
Contributed by Lukas
In this episode, Martin shares what he considers the easiest short opportunity in the market right now — and clarifies that he’s not referring to ...
Episode 825: HIMS Turning Into a Binary Bet; My Prediction. Tylenol Autism Drama, OPEN stock drops
25 Sep 2025
Contributed by Lukas
In this episode, Martin shares his view that HIMS is evolving into a binary investment and outlines his prediction for the stock’s future. He also d...
Episode 824: Burned by the Joby Short. NVDA & OpenAI Deal, BlackRock's Investor Bullish on Quantum
24 Sep 2025
Contributed by Lukas
In this episode, Martin reviews the outcome of his short position in Joby and the lessons taken from the trade. He also discusses the implications of ...
Episode 823: My Opendoor Position Ruined, Quantum Back in Full Swing. How I'm Using Options
23 Sep 2025
Contributed by Lukas
In this episode, Martin talks about how his Opendoor position was undone and analyzes the renewed activity around Quantum. He also explains how he is ...
Episode 822: Martin Reveals He Lost Millions Shorting Quantum, How This Affects Opendoor Stock
21 Sep 2025
Contributed by Lukas
In this episode, Martin details how he lost millions while shorting Quantum and explains the sequence of events that led to the trade. He also discuss...
Episode 821: OPEN's CEO Won't Talk to Me, Atyr Gains are Gone, Quantum Nightmare is Back
20 Sep 2025
Contributed by Lukas
OPEN’s CEO is dodging calls, Atyr’s gains have vanished, and quantum investing is making noise again. Here’s what went down:– Ghosted by OPEN’...
Episode 820: GALT Will Pay Us TWICE. Opendoor Stock is Value Short. When Atyr Got Too Obvious
18 Sep 2025
Contributed by Lukas
In this episode, Martin discusses why he believes GALT presents an opportunity that could pay off twice and analyzes his view on Opendoor as a value s...
Episode 819: Literally Gamestop 2.0. My Gains Are Gone. Opendoor Forecast
18 Sep 2025
Contributed by Lukas
In this episode, Martin talks through recent market moves he compares to a “Gamestop 2.0” scenario and reflects on how those shifts impacted his o...
Episode 818: $4 Million Evaporated. How 2 Portfolio Sizing, Kelly Criterion, HIMS vs FDA, Opendoor Martin Shkreli
17 Sep 2025
Contributed by Lukas
In this episode, Martin recounts how a $4 million position quickly evaporated and uses the experience to illustrate lessons in portfolio sizing and th...
Episode 817: Want Even More Easy Money？ HIVE & Celestica Stock Analysis
16 Sep 2025
Contributed by Lukas
In this episode, Martin explores potential opportunities he sees for “easy money,” focusing on his analysis of HIVE and Celestica stocks. He revie...
Episode 816: Atyr Demolished, Opendoor Next. Revealing my Trading Prediction Tool ｜ OPEN stock
16 Sep 2025
Contributed by Lukas
In this episode, Martin reviews the sharp decline in Atyr and considers whether Opendoor could be next. He also introduces his trading prediction tool...
Episode 815: Monday Will SUCK for Many Retailers . IONQ Investor Day Review
13 Sep 2025
Contributed by Lukas
In this episode, Martin looks ahead to challenges he expects many retailers will face on Monday and breaks down the potential market impact. He also r...
Episode 814: The Shopify COO is Good, But Not Enough, Atyr Phase 1 Study Analysis
12 Sep 2025
Contributed by Lukas
In this episode, Martin comments on Shopify’s leadership, noting the strengths of its COO while questioning whether that alone is sufficient for the...
Episode 813: Huge Microsoft–Nebius Deal, I’m Still Bearish. Atyr now at 50⧸50 Possibility?
10 Sep 2025
Contributed by Lukas
In this episode, Martin examines the significance of a major deal between Microsoft and Nebius while maintaining his bearish stance. He also updates h...
Episode 812: Misleading Cashflow Statement Exposed. Big Short ｜ Atyr, Okto, Opendoor Stock
09 Sep 2025
Contributed by Lukas
In this episode, Martin breaks down how a cashflow statement can be misleading and explains what he uncovered in his analysis. He also discusses his s...
Episode 811: The Problem is That it Actually Works. Market Prediction Tool, IMNB vs Atyr Stock
06 Sep 2025
Contributed by Lukas
In this episode, Martin discusses the effectiveness of his market prediction tool and how it influences his trading decisions. He also compares IMNB a...