'Why we do What we do in Cardiology'

REDUCE-AMI Trial: Diminishing Role of Beta-Blockers in ACS with preserved LVEF

24 Jun 2024

Contributed by Lukas

1. The REDUCE-AMI trial showed no significant benefit of beta-blockers in reducing all-cause mortality or future myocardial infarction in patients wit...

Improving Left Ventricular Ejection Fraction in Heart Failure Patients: Insights from the HF-OPT Study

22 Jun 2024

Contributed by Lukas

The HF-OPT study investigated the improvement of left ventricular ejection fraction (LVEF) beyond 90 days in patients with newly diagnosed heart failu...

AI in Cardiovascular Medicine: JACC Review

21 Jun 2024

Contributed by Lukas

Overview: This review discusses the use and future directions of AI in cardiology, focusing on areas like electrocardiography, telemetry and wearabl...

2024 ACC Peripheral Artery Disease (PAD) Guidelines

31 May 2024

Contributed by Lukas

Collaborative vascular care is emphasized to address health disparities, gaps in medical therapy, structured exercise, and good foot care along with...

2024 ACC/AHA Guidelines on Hypertrophic Cardiomyopathy

21 May 2024

Contributed by Lukas

2024 HCM Guidelines Focus on Cardiac Myosin Inhibitors and Exercise Mavacamten: Class 1 recommendation for symptomatic obstructive HCM. Exercise: N...

DOACs: When direct oral anticoagulants should not be used?

29 Jan 2024

Contributed by Lukas

Key Points: Positive Aspects of DOACs: DOACs are acknowledged for their convenience, efficacy, and safety in conditions like atrial fibrillation (AF...

Cath: NPO vs Eating before Heart Cath

26 Jan 2024

Contributed by Lukas

Background: Traditional practice requires fasting before cardiac catheterization, but there's no evidence to support it. Objective: This study com...

Stable CAD and Angina: PCI without medical therapy as first treatment (ORBITA-2)

22 Jan 2024

Contributed by Lukas

Key Points In patients not taking antianginal meds, PCI alleviated some—but not all—symptoms Background: Percutaneous coronary intervention (PC...

Acute CHF: GDMT Up-titration After Hospitalization for Acute HF (STRONG-HF Trial)

19 Jan 2024

Contributed by Lukas

Study: STRONG-HF trial examined rapid up-titration of heart failure medications (GDMT) after hospitalization. Goal: Reach optimal GDMT doses within 2 ...

LIPIDS: Treat to Target or with High Intensity (LODESTAR Trial)

15 Jan 2024

Contributed by Lukas

Key Points from "Treat to Target or With Intensity? Both Statin Tactics Cut MACE: LODESTAR": The study compares two strategies for managing ...

Tricuspid Regurgitation: TEER for severe TR (Triluminate Pivotal Trial)

12 Jan 2024

Contributed by Lukas

Key Points of the Study: T-TEER with the TriClip device significantly improved health status in patients with severe tricuspid regurgitation (TR) comp...

PAD: PROMISE II Trial: Deep-Vein Arterialization Shows Promise for No-Option CLTI Patients.

08 Jan 2024

Contributed by Lukas

Key Points from PROMISE 2 Trial: • Problem: 20% of CLTI patients have no revascularization options, leading to amputations. • Solution: Transcathe...

Degenerative MR: Two Choices now for Mitral Transcatheter Repair (TEER): Clasp IID Trial

05 Jan 2024

Contributed by Lukas

Key Points from this trial: The CLASP IID trial, the first randomized controlled trial comparing the PASCAL system and the MitraClip system in prohib...

Sinus Node Disease: DANPACE II trial: Study Debunks Pacing Myth: Minimizing Pacing Doesn't Curb A-Fib

01 Jan 2024

Contributed by Lukas

Key points of the DANPACE II study on atrial pacing and atrial fibrillation in sinus node dysfunction: 1. Minimizing atrial pacing in pacemakers doesn...

Major Trends in Cardiology from 2023

31 Dec 2023

Contributed by Lukas

Major Trends: Independent Medical Board: Cardiologists seek a new board separate from the ABIM due to concerns with MOC requirements. Scope of Pra...

CAD: Coronary Artery Disease Updates in 2023

25 Dec 2023

Contributed by Lukas

Key Points of Coronary Artery Disease Studies in 2023: • ORBITA-2: Confirmed PCI's role in relieving angina symptoms for stable patients. • SE...

CHF: Major News and Trial Updates in CHF in 2023

20 Dec 2023

Contributed by Lukas

A quick rundown of the key developments: Trials: STEP-HFpEF CASTLE-HTx HEART FID DAPA-MI Policy and Guidelines: ESC cardiomyopathy guidelin...

Valvular HD: 2023 Structural Highlights

15 Dec 2023

Contributed by Lukas

Focus on Valves: TAVI vs. SAVR: Long-term data showed mixed results. PARTNER 3 (Sapien 3 valve) benefits declined over time, while Evolut Low Risk ...

CVD: 2023 Major Updates in General Cardiology

10 Dec 2023

Contributed by Lukas

Key Highlights: Lodoco is the first anti-inflammatory approved for reducing cardiovascular events in ASCVD patients. Bempedoic acid offers an alt...

PAD: Peripheral Arterial Disease Updates from 2023

05 Dec 2023

Contributed by Lukas

Key Points of Endovascular Procedures and Devices in 2023: FDA Actions: Lifted restrictions on paclitaxel-coated balloons and stents for PAD after ...

Electrophysiology: Important EP Updates from 2023

30 Nov 2023

Contributed by Lukas

Heart Rhythm 2023: Innovations in Ablation, Devices, and Conduction System Pacing. Catheter Ablation and LAAO Advance: CASTLE-HTx: Ablation for AF...

PCI: Complete PCI in ACS and multi-vessel CAD, a systematic review

19 Oct 2023

Contributed by Lukas

Key Points: Multi-vessel coronary disease (MVD) in acute myocardial infarction (AMI) is still a difficult condition to manage. Complete revasculari...

Afib: FRAIL-AF Trial: Anticoagulation in Frail Older Patients with Afib

11 Sep 2023

Contributed by Lukas

Key findings of the FRAIL-AF trial: * Switching from vitamin K antagonist (VKA) to non-vitamin K antagonist oral anticoagulant (NOAC) therapy was as...

CHF: Semaglutide in HFpEF across obesity classes (STEP-HFpEF trial)

03 Sep 2023

Contributed by Lukas

Summary of the STEP-HFpEF trial 2023 published in Nature Medicine The STEP-HFpEF trial was a study of semaglutide in patients with obesity phenotype...

Acute MI: Complete or Culprit-Only PCI in Older Patients with MI (FIRE trial)

03 Sep 2023

Contributed by Lukas

Key points of the FIRE trial: The study was a randomized trial of complete revascularization vs. culprit-only revascularization in older patients ...

CAD: ACC/AHA 2023 Chronic Coronary Disease Guideline Key Points: J Am Coll Cardiol. 2023 Aug, 82 (9) 956–960

30 Aug 2023

Contributed by Lukas

These are the key points from this 2023 ACC/AHA guideline in managing chronic coronary disease. Patients with chronic coronary disease should rece...

Cardiomyopathy: TTR Amyloid: efficacy and safety of acoramidis in transthyretin amyloid cardiomyopathy - ATTRibute-CM Trial, ESC Meeting August 2023

28 Aug 2023

Contributed by Lukas

The ATTRibute-CM trial was a randomized, double-blind, placebo-controlled trial that evaluated the efficacy and safety of acoramidis in patients with ...

Cardiac arrest: Expedited transfer to a cardiac arrest center for non-ST-elevation out-of-hospital cardiac arrest-The ARREST trial: The Lancet, August 2023

27 Aug 2023

Contributed by Lukas

Key Points from ARREST trial findings: The study included 862 patients who were resuscitated after a cardiac arrest. The patients were randomly ass...

Infective Endocarditis: 2023 ESC Guidelines for the management of endocarditis in European Heart Journal

26 Aug 2023

Contributed by Lukas

Here is a summary of the key points from the 2023 ESC guidelines for the management of endocarditis: Prevention: People at high risk of endocarditi...

LAA: Comparison of Initial Antithrombotic Regimens after Left Atrial Appendage Occlusion: JACC Aug 2023

22 Aug 2023

Contributed by Lukas

This review highlights the following points: There are different ways to prevent blood clots in patients who have undergone LAAO for atrial fibrilla...

CAD: Low-Dose Colchicine for Secondary Prevention of CAD: JACC Aug 2023

21 Aug 2023

Contributed by Lukas

The review article was published in the Journal of the American College of Cardiology in August 2023 and was co-authored by Dr. Kyle Nelson, Dr. Vale...

CAD: A Practical Approach to Left Main Coronary Artery Disease 2022

06 Dec 2022

Contributed by Lukas

LM CAD treatment needs sophisticated decision-making. Recent clinical practice standards guide clinicians; however, treating individual individuals mi...

PAD: Screening for Asymptomatic Carotid Artery Stenosis 2021

19 Nov 2022

Contributed by Lukas

Screening for Asymptomatic Carotid Artery Stenosis in the General Population: Updated Evidence Report and Systematic Review for the US Preventive Serv...

Cardiomyopathy: Cardiac Amyloidosis-2020 Update

14 Jun 2020

Contributed by Lukas

The understanding, diagnosis, and treatment options for transthyretin (TTR) amyloid is rapidly evolving. American Heart Association published a statem...

'Why we do What we do in Cardiology' (Trailer)

13 Jun 2020

Contributed by Lukas