前两年有一句毒鸡汤,“成年人的生活,除了容易胖,其他都不容易。”虽然是个俏皮话,但是,不得不承认“减肥”是当代人生活中绝对的高频词,社交媒体上也都充斥着各种减肥的话题。各种各样的减肥方法层出不穷。或许瘦人们永远不会去试图了解一种叫“生酮饮食”的方法。有人觉得这种方法神奇;有人觉得不好坚持;医生会说这种方法十分危险……我相信不少人看到过这个名词,这一期,我们想从微观出发,从细胞层面,解读生酮饮食对人体造成的影响,也会基于权威研究,聊一聊生酮饮食在临床上的应用,以及不当尝试的副作用。这一期我们大概聊了: 0:30连续减肥者(玉米)第一次聊减肥话题 3:15生酮饮食能减肥的基本原理是什么 7:42生酮饮食后身体在微观层面发生了哪些变化 16:09生酮饮食为什么可以作为很多疾病的辅助治疗甚至主要治疗手段(糖尿病、心脏病、脂肪肝、癌症、多囊卵巢综合症、神经系统疾病) 33:02要想生酮,都有哪些东西不能吃或者能吃呢? 37:52生酮饮食亲历者介绍生酮食谱,以及为什么没有坚持下去? 46:30分享三位生酮饮食受访者的状态 49:30生酮饮食为什么难以坚持? 51:30生酮饮食有哪些副作用? 1:07:02医生提醒,“生酮是治疗,如同‘处方药’,而不是随便吃吃的问题,一定要在医生指导下进行”参考文献: Lin, H., Suzuki, K., Smith, N. et al. A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding. Nat Commun 15, 334 (2024). Long F, Bhatti MR, Kellenberger A, et al. A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice. Mol Metab. 2023;69:101675. doi:10.1016/j.molmet.2023.101675 Kawon K, Rugiel M, Setkowicz Z, Matusiak K, Kubala-Kukus A, Stabrawa I, Szary K, Rauk Z, Chwiej J. Ketogenic diet influence on the elemental homeostasis of internal organs is gender dependent. Sci Rep. 2023 Oct 27;13(1):18448. doi: 10.1038/s41598-023-45611-4. PMID: 37891248; PMCID: PMC10611712. Crosby L, Davis B, Joshi S, et al. Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks. Front Nutr. 2021;8:702802. Published 2021 Jul 16. doi:10.3389/fnut.2021.702802 Sampath A, Kossoff EH, Furth SL, Pyzik PL, Vining EP. Kidney stones and the ketogenic diet: risk factors and prevention. J Child Neurol. 2007 Apr;22(4):375-8. doi: 10.1177/0883073807301926. PMID: 17621514. Olson CA, Iñiguez AJ, Yang GE, et al. Alterations in the gut microbiota contribute to cognitive impairment induced by the ketogenic diet and hypoxia. Cell Host Microbe. 2021;29(9):1378-1392.e6. doi:10.1016/j.chom.2021.07.004#song list Frozen - 7AND5 Wood Window - Jannik 桜 - コブクロ 風見鶏 (风向仪) MTD bass 独奏版本 - 亨头_Hento 听友群加VX:hooley777商务合作:[email protected](诚招冠名、植入、定制单集合作伙伴)
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