这两天,“新冠”两个字又赫赫上了热搜……回想起来,拜登阳、奥运选手阳、南美奥罗普切热、非洲猴痘……2024年的这个夏天,微生物仍然搅动着,让世界不太平。一直以来,关注微生物是万物生长FM的“传统艺能”,这一期我们从新冠从发,聊聊最近在以巴西为主的南美洲流行的奥罗普切热,是个什么病毒?科学家是怎么发现它的?传播途径有哪些?发展至今病毒有哪些新变异?以及有没有可能向世界其他地方蔓延?同时,我们也探讨了为什么近几年微生物带来的传染病如此之多。时间轴:0:50身边又有不少人阳了不是错觉2:12 为什么新冠总是冬天一波、夏天一波?4:35 正在巴西流行的奥罗普切是个什么病毒?9:22 揭秘奥洛普切病毒:从发现至今的研究历程?14:32 奥罗普切的传播途径有哪些,该怎么防控?20:49 奥罗普切在南美爆发的影响25:07 如果想去巴西旅游,有哪些风险提示28:45 奥罗普切会不会传播到国内以及世界其他地方?31:40 为什么最近几年微生物带来的疫情越来越多?38:00 面对微生物,而不是逃避#参考资料 ANDERSON CR, SPENCE L, DOWNS WG, AITKEN TH. Oropouche virus: a new human disease agent from Trinidad, West Indies. Am J Trop Med Hyg. 1961;10:574-578. doi:10.4269/ajtmh.1961.10.574 Pinheiro FP, Travassos da Rosa AP, Gomes ML, LeDuc JW, Hoch AL. Transmission of Oropouche virus from man to hamster by the midge Culicoides paraensis. Science. 1982;215(4537):1251-1253. doi:10.1126/science.6800036 Livonesi MC, de Sousa RL, Badra SJ, Figueiredo LT. In vitro and in vivo studies of the Interferon-alpha action on distinct Orthobunyavirus. Antiviral Res. 2007;75(2):121-128. doi:10.1016/j.antiviral.2007.01.158 de Souza Luna LK, Rodrigues AH, Santos RI, et al. Oropouche virus is detected in peripheral blood leukocytes from patients. J Med Virol. 2017;89(6):1108-1111. doi:10.1002/jmv.24722 Barbosa NS, Mendonça LR, Dias MVS, et al. ESCRT machinery components are required for Orthobunyavirus particle production in Golgi compartments. PLoS Pathog. 2018;14(5):e1007047. Published 2018 May 3. doi:10.1371/journal.ppat.1007047 Sakkas H, Bozidis P, Franks A, Papadopoulou C. Oropouche Fever: A Review. Viruses. 2018;10(4):175. Published 2018 Apr 4. doi:10.3390/v10040175 Nascimento VAD, Santos JHA, Monteiro DCDS, et al. Oropouche virus detection in saliva and urine. Mem Inst Oswaldo Cruz. 2020;115:e190338. Published 2020 Feb 27. doi:10.1590/0074-02760190338#song list • Cello Suite No. 1 in G Major, BWV 1007:I. Prélude - Janos Starker • Love From Me-Johnson Rodgie • Study With Me - Snuggles • Mark Masri - Santa Lucia听友群加VX:hooley777商务合作:[email protected](诚招冠名、植入、定制单集合作伙伴)
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