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天方烨谈

不对称的完美:肠道是如何“保持默契”旋转形成的?

16 Nov 2022

Description

近日,发表在《Science》上的一项最新研究中,来自康奈尔大学的研究团队他们发现,发育过程中的肠道旋转是由具有双重作用的转录因子Pitx2的两波表达协调的,在第二波表达中,Pitx2驱动了肠道不对称性地旋转。这些发现对于理解器官形成的基本机制具有重要意义,并为预防和诊断出生缺陷提供了线索。

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