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作为预防心血管疾病的常用药，阿司匹林也有过失败的临床试验。比如2018年发布在《新英格兰医学杂志》上的ASPREE试验就显示：服用阿司匹林，与健康老年人的死亡风险上升有关，而主要原因可能是因癌死亡率的上升。近期在《美国国家癌症研究所杂志》（JNCI）上，ASPREE试验的研究者们发表了对试验数据的进一步分析：服用阿司匹林可能促进了癌症的进展和转移，从而使更多的老年人确诊存在远处转移的IV期癌症！
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