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健康捐献者的造血干细胞移植,可以治愈或改善各种非恶性疾病的病理,包括原发性免疫缺陷疾病、血红蛋白病、骨髓衰竭综合征和先天性代谢紊乱等。然而,未经化疗的患者干细胞移植失败的发生率较高,限制了其广泛应用。近日,匹兹堡大学的研究人员用脐带血成功治疗了儿童罕见遗传病,而且失败率大大降低。这项研究由匹兹堡大学医学中心匹兹堡儿童医院的Paul Szabolcs博士领导,并发表在《Blood Advances》上。
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