最近Weill Cornell Medicine Christopher E. Mason领导的团队在预印本发表了人体解剖空间图谱The Spatial Atlas of Human Anatomy (SAHA)。这是一个前所未有的多模态、亚细胞分辨率参考资源，涵盖了健康成人体内的胃肠道和免疫系统。通过整合空间转录组学、蛋白质组学和组织学数据，SAHA 详细描绘了细胞组织、细胞间相互作用和组织微环境。这项工作不仅提供了正常组织的高分辨率基线，还通过与结直肠癌和炎症性肠病等疾病的比较分析，展示了其在疾病诊断和精准医学方面的潜力。所有数据均通过开放访问门户提供，旨在促进未来空间生物学研究。References: The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs. bioRxiv 2025.06.16.658716; doi: doi.org
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