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聊聊Sci

005-神经元通过线粒体转移促进癌症扩散🧠

27 Jun 2025

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Nature 《News & views》栏目中的一篇文章概述了胡佛及其同事的发现,强调了癌细胞获取神经元线粒体以促进其扩散的能力。线粒体,作为细胞的能量中心,在代谢中扮演着核心角色。文章指出,癌细胞可以通过从神经元获取线粒体来增强其代谢能力,变得更能抵抗压力,并提高其“干性”特征,从而促进癌细胞在体内的扩散。此外,文章还讨论了线粒体如何在细胞间转移,包括自由漂浮、通过囊泡或通过隧穿纳米管,并重点介绍了胡佛团队使用MitoTRACER工具追踪这一过程。

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