此文本探讨了癌症的标志与神经科学之间的新兴联系(Cancer Hallmarks and Neurobiology: A Tumoral Intersect)，指出神经系统在肿瘤发生和恶性进展中的多方面作用。文章详细阐述了神经对肿瘤增殖信号、抵抗细胞死亡、侵袭和转移以及促进炎症的影响。此外，它还讨论了癌细胞如何利用神经调节回路来促进肿瘤生长和免疫逃逸，强调了肿瘤微环境中神经支配和癌细胞中神经信号通路的共同作用。最终，文章提出将神经系统连接视为癌症标志概念中的一个重要组成部分，因为它对多种肿瘤类型的核心功能具有深远影响。References: Hanahan D, Monje M. Cancer hallmarks intersect with neuroscience in the tumor microenvironment. Cancer Cell. 2023 Mar 13;41(3):573-580. doi: 10.1016/j.ccell.2023.02.012. PMID: 36917953; PMCID: PMC10202656.
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