这篇文章讨论了微生物组研究在临床医学中的应用现状与挑战。尽管微生物组在诊断和治疗方面展现出巨大潜力,但其在临床实践中的普及仍面临障碍,例如粪便微生物移植(FMT)虽已获批用于艰难梭菌感染,但在其他适应症方面仍停留在研究阶段。文章强调了标准化研究方法、改进临床试验设计、以及加强微生物组研究人员与临床医生之间沟通的重要性,以期将微生物组科学更有效地转化为临床应用。References: Porcari S, Ng S C, Zitvogel L, et al. The microbiome for clinicians[J]. Cell, 2025, 188(11): 2836-2844.
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