这篇综述主要讨论了人类大脑进化的机制,重点关注了人类认知能力的生物学基础。文章追溯了从简单神经系统到复杂脊椎动物大脑的进化历程,并比较了人类与近亲物种大脑在神经解剖学、细胞构成和基因组层面的异同。文章还探讨了诸如脑容量扩张、神经发生差异以及神经元成熟延迟等人类特有的发展机制。最后,文本展望了利用新型体外模型和基因编辑技术来更深入地揭示人类大脑进化奥秘的未来研究方向。References: Lancaster M A. Unraveling mechanisms of human brain evolution[J]. Cell, 2024, 187(21): 5838-5857.
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