这篇综述文章主要探讨了大脑边界相关巨噬细胞（BAMs）在维持大脑稳态和免疫功能中的关键作用。文章详细介绍了BAMs的解剖位置，包括脑膜、血管周围空间、脉络丛和脑室旁器官，这些区域共同构成了大脑与外周环境的接口。文中还阐述了BAMs的不同亚群和细胞状态，并追溯了它们从胚胎发育到成年甚至衰老过程中的起源和动态变化。此外，文章强调了BAMs在组织和血管稳态调节中的重要功能，以及它们在抵抗病原体入侵和调节神经炎症中作为免疫守门人的角色。References: Vara-Pérez M, Movahedi K. Border-associated macrophages as gatekeepers of brain homeostasis and immunity[J]. Immunity, 2025, 58(5): 1085-1100.
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