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这篇文章概述了干细胞在细胞生物学中的关键作用，重点介绍了它们在组织修复和细胞重编程中的潜力。作者们探讨了不同类型的干细胞，从多能干细胞到组织特异性干细胞，并解释了它们分化成各种细胞类型的机制。文章还详细阐述了诱导多能干细胞（iPSC）的发展，以及直接重编程如何启发了创新疗法，超越了传统干细胞应用。最后，文章回顾了干细胞和重编程策略在临床试验中的进展，强调了它们在治疗各种疾病方面的前景。References: Götz M, Torres-Padilla M E. Stem cells as role models for reprogramming and repair[J]. Science, 2025, 388(6746): eadp2959.
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