这篇文章探讨了饮食与微生物组相互作用在癌症发生、发展、扩散和治疗反应中的复杂联系。文章详细阐述了饮食构成（如碳水化合物、脂肪、蛋白质、矿物质和维生素）如何通过改变微生物群落来影响癌症相关过程，并强调了饮食时间（包括限时进食和模拟禁食饮食）对微生物功能调节癌症及其治疗的重要性。此外，文章还审视了旨在增强微生物介导的癌症治疗反应并最大程度减少不良反应的现有及实验性营养方法，并讨论了将饮食-微生物组相互作用整合到精准肿瘤学中面临的挑战和前景，最终旨在实现个性化和微生物组指导的营养癌症干预优化。References: Abdeen S K, Mastandrea I, Stinchcombe N, et al. Diet-microbiome interactions in cancer[J]. Cancer Cell, 2025, 43(4): 680-707.
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