这篇综述文章深入探讨了肿瘤血管生成与肿瘤免疫之间的复杂相互作用，重点关注它们如何影响癌症进展和免疫疗法结果。文章解释了异常肿瘤血管如何通过限制免疫细胞渗透并营造免疫抑制性微环境来阻碍有效的抗肿瘤免疫反应。研究人员还阐述了通过血管正常化改善抗肿瘤免疫力的方法，以及血管正常化与免疫检查点阻断（ICB）疗法之间的协同作用。文章讨论了当前抗血管生成策略的局限性，并提出了未来的研究方向，以优化癌症治疗方案，例如结合抗血管生成和免疫治疗方法，以及探索非血管内皮生长因子（VEGF）通路靶点以减少副作用。文章总结道，将抗血管生成疗法与免疫疗法结合具有巨大潜力，但在更广泛应用之前仍需解决安全性问题并优化治疗策略。References: Kabir A U, Subramanian M, Kwon Y, et al. Linking tumour angiogenesis and tumour immunity[J]. Nature Reviews Immunology, 2025: 1-1
No persons identified in this episode.
This episode hasn't been transcribed yet
Help us prioritize this episode for transcription by upvoting it.
Popular episodes get transcribed faster
Other recent transcribed episodes
Transcribed and ready to explore now
Trump $82 Million Bond Spree, Brazil Tariffs 'Too High,' More
16 Nov 2025
Bloomberg News Now
Ex-Fed Gov Resigned After Rules Violations, Trump Buys $82 Mil of Bonds, More
16 Nov 2025
Bloomberg News Now
THIS TRUMP INTERVIEW WAS INSANE!
16 Nov 2025
HasanAbi
Epstein Emails and Trump's Alleged Involvement
15 Nov 2025
Conspiracy Theories Exploring The Unseen
New Epstein Emails Directly Implicate Trump - H3 Show #211
15 Nov 2025
H3 Podcast
Trump Humiliates Himself on FOX as They Call Him Out
15 Nov 2025
IHIP News