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聊聊Sci

121-肿瘤中性粒细胞的早期重塑

24 Sep 2025

Description

这篇文章讨论了肿瘤对造血系统的全身性影响,特别是肿瘤衍生的信号如何在骨髓早期重编程中性粒细胞,赋予它们免疫抑制特性,并提出阻断 IL-1β 可以作为逆转这种病理重编程和减少癌症转移的潜在治疗策略。References: Dong L, Ng L G. Tumor neutrophils rewired from birth[J]. Cancer Cell, 2025.

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