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聊聊Sci

200-脑肿瘤的神经科学

01 Nov 2025

Description

这篇文章概述了神经元活动如何强有力地驱动包括成人和儿童高级别胶质瘤在内的脑癌的发生、生长、侵袭和治疗抵抗。这些机制包括神经元活动调控的旁分泌信号和神经元-胶质瘤突触的直接电化学通讯。此外,文章还探讨了脑癌如何反过来重塑神经回路,增加兴奋性,从而加剧肿瘤的促进效应,并讨论了这些原则对其他原发性和转移性脑癌的影响,强调了从神经科学角度研究癌症的重要性。References: Monje, Michelle. "The neuroscience of brain cancers." Neuron 113.17 (2025): 2734-2739.

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