欢迎收听今日医学新发现!最新研究揭示,儿童间充质肿瘤种类繁多,包括血管、纤维/肌纤维母细胞和肌源性肿瘤,这些肿瘤在形态和免疫表型上相互重叠,给诊断带来挑战。幸运的是,免疫组化技术的新进展已帮助识别部分肿瘤的特定分化线路。分子研究不仅加深了我们对这些肿瘤发病机制的理解,还在某些情况下,如EWING家族肿瘤,扩展了分类范围。现在,一些肿瘤根据其分子异常进行诊断,例如CIC重排肉瘤和BCOR重排肉瘤等。这项研究为我们提供了儿童常见间充质肿瘤的重要显微镜下特征、免疫谱和分子特性,为我们更好地理解和治疗这些复杂疾病提供了宝贵的信息。不要错过这一突破性进展!
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