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欢迎来到科研喵，使用AI读文献，祝你效率百倍。现在访问labcat.com.cn下载我们的App，开始你的科研加速之旅。今天的头条医学研究新闻，给我们带来了对抗肾细胞癌的新希望。研究发现，通过共递送Axitinib和PD-L1 siRNA，可以同时实现血管正常化和免疫检查点抑制，增强抗癌免疫反应。这种方法不仅能够改善肿瘤血管结构，提高免疫细胞的渗透，还能够降低PD-L1蛋白的表达，恢复细胞毒性T细胞的识别和杀伤能力，从而显著提高抗肿瘤和抗转移效果。这项研究为我们提供了一种新的策略，通过调节异常肿瘤血管，重塑免疫抑制微环境，增强癌症免疫疗法的效果。这不仅是一个科学突破，更是肾细胞癌患者的一线希望。
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