欢迎收听科研喵播客,用AI读文献,效率百倍。访问labcat.com.cn下载app。今天的焦点研究来自《Cancer cell》杂志,一篇关于癌症中细胞衰老的论文。研究发现,细胞衰老是一种由多种内外因素引起的稳定细胞周期停滞状态,对防止受损细胞增殖至关重要。然而,随着时间的推移,衰老细胞的积累与年龄相关的疾病,包括免疫功能障碍和癌症有关。本综述探讨了癌症中衰老的特征、与肿瘤细胞、基质和免疫系统的复杂相互作用,以及依赖于上下文的结果。我们还讨论了针对衰老细胞的当前和新兴治疗策略,无论是诱导还是消除它们,以及AI驱动的方法,用于在癌症中检测和表征它们。
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