欢迎收听科研喵播客,使用AI读文献,效率百倍,快来labcat.com.cn下载体验吧!最新研究揭示,MicroRNA-7(miR-7)是肿瘤糖酵解代谢的多面调节器。研究发现,miR-7通过直接靶向葡萄糖转运蛋白和糖酵解酶,抑制肿瘤细胞的葡萄糖摄取和糖酵解通量。此外,它还调节HIF-1α/ENO2轴和免疫检查点表达,重塑免疫抑制微环境,促进代谢与免疫的交叉对话。这些发现突出了miR-7在肿瘤代谢调控中的独特作用,并为其作为治疗靶点提供了新视角,为精准肿瘤学策略的发展提供了新思路。不要错过这一突破性进展,深入了解miR-7如何影响肿瘤代谢和免疫调控,尽在本期播客。
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