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科研喵使用AI读文献，祝你效率百倍，访问LabCat.com.cn下载。最新研究发现，CAR-T细胞疗法在血液肿瘤治疗中取得了显著成效，但传统病毒转导技术存在插入突变风险。一项发表在《分子医学趋势》杂志的研究，由Xiao Y团队领衔，探讨了一种新兴的非病毒基因工程技术，利用mRNA和脂质纳米颗粒（LNPs）进行CAR工程，以提高细胞疗法的安全性和可负担性。这项技术不仅有望为癌症治疗带来突破，还可能应用于非癌症疾病的免疫疗法，预示着未来个体化免疫治疗的新方向。
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