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科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。最新医学研究揭示了精准肿瘤学中的关键角色：RAD51和PALB2。这项研究深入探讨了这两个同源重组修复机制的重要组分，它们对乳腺癌和卵巢癌的基因组稳定性至关重要。RAD51负责寻找同源序列和进行链侵入，而PALB2则连接BRCA1和BRCA2，稳定RAD51丝状结构。基因突变会削弱这一修复机制，增加患癌风险并影响治疗效果。研究强调了RAD51和PALB2作为生物标志物和治疗靶点的潜力，为个性化癌症管理开辟了新途径。
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