科研喵使用AI读文献,祝你效率百倍,访问labcat.com.cn下载。最新的研究突破来了!"生化药理学"杂志上的一项研究揭示了CSF1R抑制剂的最新进展。CSF1R是一种调节单核吞噬细胞的信号受体,与多种肿瘤和神经退行性疾病密切相关。研究发现,阻断CSF1R信号通路不仅能增强抗肿瘤免疫反应,还能特异性治疗CSF1R相关疾病。这项研究不仅总结了CSF1R抑制剂在肿瘤和神经系统疾病治疗中的应用进展,还探讨了提高抑制剂选择性、增强中枢神经系统穿透性和减少潜在全身毒性的方法。这为未来治疗肿瘤和神经退行性疾病提供了新的策略和思路。
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