欢迎收听科研喵播客,使用AI读文献,效率百倍。立即访问labcat.com.cn下载我们的app。今天的热点研究来自《自然》杂志,揭示了如何通过扩展细胞因子受体配对,重新编程T细胞至多样化状态。研究人员利用非自然的JAK-STAT受体配对在T细胞上诱导独特的基因表达模式,导致肿瘤中T细胞分化为不同的亚型,包括具有吞噬能力的髓样T细胞和抗肿瘤特性增强的干细胞样T细胞。这项研究不仅拓宽了我们对T细胞功能的理解,还为癌症治疗提供了新的策略。不要错过这一突破性发现,继续关注科研喵,探索科学的边界。
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