欢迎收听科研喵播客,用AI读文献,助你效率百倍!立即访问labcat.com.cn下载。今天的亮点研究来自《细胞》杂志,哈佛医学院和波士顿儿童医院的Boehmer博士团队发现,干扰素(IFNs)是一类在健康和疾病中扮演关键角色的信号蛋白。它们不仅能在细菌、病毒、真菌感染中发挥保护作用,也可能引发炎症和自身免疫疾病。这篇综述深入探讨了干扰素的细胞和分子机制,揭示了它们在感染、肿瘤、炎症和自身免疫性疾病中的重要作用,尤其是对粘膜组织的影响。研究强调,不同干扰素家族成员的平衡产生对发挥保护作用至关重要,失衡则可能对宿主造成损害。这一发现为我们理解干扰素在疾病中的作用提供了新的视角。
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